Clinical pharmacist interventions in the identification and prevention of problems related to pharmacotherapy in a tertiary teaching hospital

Authors

DOI:

https://doi.org/10.33448/rsd-v11i14.35760

Keywords:

Pharmaceutical care; Pharmaceutical Interventions; Clinical Pharmacy; Drug-Related Problems; Patient safety.

Abstract

The present study aims to analyses the pharmaceutical interventions in the identification and prevention of problems related to pharmacotherapy. This study has a quantitative, transversal and descriptive approach. Data were obtained in the period from January to November 2021. All patients admitted to a University Hospital in Sergipe, within the period described above, who required pharmaceutical intervention, were included in this study. Therefore, the variables of interest analyzed were divided into three axes: I) patient data: a) age, b) sex and c) comorbidities; II) problems related to detected drugs and III) pharmaceutical interventions carried out and their acceptability. After collection, data were recorded separately in Microsoft Excel® spreadsheets and analyzed using central tendency techniques. The population studied comprised 357 patients, the majority being male (53%; n=191), with at least one comorbidity, mostly hypertension (48.4%; n=205), diabetes (27%; n=115) and dyslipidemia (6%; n=26). Most interventions (64%; n=325) were accepted and most of these were related to dose adjustment, missing medication, need for additional medication and route of administration. Of the pharmaceutical interventions that were not accepted, it was observed that 26% (n=129) of prescribers did not justify it and 10% (n=52) did it. In view of the results presented, it can be seen that most pharmaceutical interventions were accepted, which may be related to the advancement of understanding of the role of the clinical pharmacist in the health team. These changes bring benefits in clinical outcomes and pharmacoeconomics parameters, since the performance of the multidisciplinary team aims to promote adequate and safe pharmacotherapy for the patient, through the prevention of drug-related problems as well as their rational use.

Author Biographies

Damaris Santana Cardoso , Universidade Federal de Sergipe

Pharmacist from the Federal University of Sergipe (2016). Specialist in quality of magistral pharmacy and Clinical Pharmacy and Pharmaceutical Care an Hospital Health Care. Has experience in the field of Masterful Pharmacy. Currently collaborate in a Drug Information Center (CIMUFS-Lag).

Izadora Menezes da Cunha Barros, Universidade Federal de Sergipe

Pharmacist graduated from Tiradentes University (2010). Master in Pharmaceutical Sciences at the Federal University of Sergipe (2013). Doctor by the Postgraduate Program in Health Sciences (2016). She is currently an Adjunct Professor at the Federal University of Sergipe - UFS, at the Department of Pharmacy -DFAL of the Antônio Garcia Filho Campus (Lagarto-SE). Member of the Laboratory of Studies in Pharmaceutical Care (LECFAR) and of the Teaching and Research Group in Social Pharmacy (GEPFS). Professor of Pharmaceutical Teaching Practices in the Community and the Professional Master's Program in Management and Technological Innovation in Health (PPGITS). Develops research in the areas of Clinical Pharmacy, Pharmaceutical Assistance and Pharmaceutical Communication. Exercises tutoring activity in the Multiprofessional Residency of Hospital Care.

Júlia Santana Lisboa, Universidade Federal de Sergipe

Graduated in Pharmacy at the Federal University of Sergipe, postgraduate in Pharmaceutical Care and Clinical Pharmacy at IPOG, and also in Hospital Pharmacy. Internship at HUSE and Health Care Center in Sergipe, for 6 months each. I am a specialist in Hospital Health Care - Lagarto (HUL). I worked as a pharmacist at the Sergipe Health Care Center for 9 months, and for 5 months at the Health Promotion and Assistance Institute (IPES). I have experience in the hospital area, in extensive actions, participation in several practical courses, including the course on injectables, held at UFS; complete computer course and willing to new experiences.

References

Araújo, E. O., Viapiana, M., Domingues, E. A. M., Oliveira, G. S., & Polisel, C. G. (2017). Intervenções Farmacêuticas em uma Unidade de Terapia Intensiva de um Hospital Universitário. Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde. 8(3), 25-30. https://doi.org/10.30968/rbfhss.2017.083.005.

Araújo, E. S., Modesto, A. C. F., Ferreira, T. X., Provin, M. P., Lima, D. M., & Amaral, R. G. (2020). Intervenção farmacêutica no uso racional de omeprazol intravenoso. Einstein, 18:1-6. https://doi.org/10.31744/einstein_journal/2020AO4433.

Brasil. (2002). Organização Pan-Americana da Saúde. Consenso brasileiro de atenção farmacêutica. Brasília.

Cação, E. V., Bokehi, J. R., Futuro, D. O., & De Castilho, S. O. (2020). Fluxo montante na logística de uma farmácia escola pública: um estudo de caso. Revista de Administração Hospitalar e Inovação em Saúde. 16 (2), 81–93. https://doi.org/10.21450/rahis.v16i2.5773.

Cardoso, D. S., Matos, L. E. O., Barros, I. M. C., Lisboa, J. S., Fernandes, S. S. S., & Lima, T. C. (2022). Development of a proton pump inhibitor protocol in the prophylaxis of acute gastric mucosal injury: experience report. Research, Society and Development, 11(8), e25211830865. https://doi.org/10.33448/rsd-v11i8.30865

Cassiani, S. H. B., Teixeira, T. C. A., Opitz, S. P., & Linhares, J. C. (2005). O sistema de medicação nos hospitais e sua avaliação por um grupo de profissionais. Revista da Escola de Enfermagem da USP. 39 (3). https://doi.org/10.1590/S0080-62342005000300005.

Chaves, L. A., Chaves, G. C., Vianna, M. N. S., & Oliveira, M. A. (2019). Desabastecimento de medicamentos na literatura científica da saúde: uma revisão narrativa. Revista de Saúde Coletiva. 29 (01). https://doi.org/10.1590/s0103-73312019290107.

Conselho Federal de Farmácia. (2017). Farmácia Hospitalar: coletânea de práticas e conceitos. Brasília.

Costa, L. S. (2014). Atuação do farmacêutico em unidade de terapia intensiva: impacto da farmácia clínica no acompanhamento da terapia medicamentosa [dissertação de mestrado, Universidade Estadual de Campinas]. Repositório da Universidade Estadual de Campinas.

Cruz, L. T., Batista, P. N., & Meurer, I. R. (2019). Análise do serviço de farmácia clínica em um hospital universitário. HU Revista. 45(4). https://doi.org/10.34019/1982-8047.2019.v45.27553.

Dias, D., Wiese, L. P. L., Pereira, E. M., & Fernandes, F. M. (2019). Evaluation of pharmaceutical clinical interventions in the icu of a public hospital of Santa Catarina. Rev Bras Farm Hosp Serv Saude. 9(3). https://doi.org/10.30968/rbfhss.2018.093.005.

Ferrández, O., Casan, B., Grau, S., Louro, J., Salas, E., Castells, X., & Sala, M. (2019). Análise de problemas relacionados a medicamentos em um hospital universitário terciário em Barcelona (Espanha). Gac Sanit. 33(4), 361-368. https://doi.org/10.1016/j.gaceta.2018.01.002.

Ferreira, F. S., Pereira, T. A., Souza, B. P., & Sanches, A. C. C., (2021). O papel do farmacêutico na prevenção de erros de medicação. Research, Society and Development. 10(3). http://dx.doi.org/10.33448/rsd-v10i3.13280.

Garske, C. C. D., Freitas, A. P., Brixner, B., Machado, E. O., & Schneider, A. P. H. (2016). Acompanhamento farmacoterapêutico de pacientes atendidos em pronto atendimento em um hospital de ensino. Revista Saúde. https://doi.org/10.5902/2236583421031 .

Madridejos, R. (2013). Inhibidores de la bomba de protones y el balance riesgo/beneficio. Generalitat de Catalunya departament de salut. 24(2). https://scientiasalut.gencat.cat/bitstream/handle/11351/1024/BIT_2013_24_02_cas.pdf?sequence=7&isAllowed=y.

Maioli, N. A., & Santos, H. C. B. (2018) Intervenções Farmacêuticas e sua Importância na Segurança do Paciente Hospitalizado. Colloquium Vitae. 10(2). https://doi.org/10.5747/cv.2018.v10.n2.v229.

Milioni, K. C. (2017). Relação entre o grau de complexidade do cuidado de pacientes, nível de estresse e coping nos profissionais de enfermagem do Hospital de Clínicas de Porto Alegre. [dissertação de mestrado, Universidade Federal do Rio Grande do Sul]. Repositório da Universidade Federal do Rio Grande do Sul. https://www.lume.ufrgs.br/bitstream/handle/10183/164884/001027469.pdf?sequence=1&isAllowed=y.

Miranda, T. M. M., Petriccione, S., Ferracini, F. T., & Filho, W. M. B. (2012). Intervenções realizadas pelo farmacêutico clínico na unidade de primeiro atendimento. Einstein. 10(1). https://doi.org/10.1590/S1679-45082012000100015.

Pelentir, M.., Deuschle, V. C. K. N., & Deuschle, R. A. N. (2015) Importância da assistência e atenção farmacêutica no ambiente Hospitalar. Revista de Ciência e Tecnologia. (1)1, 20-28. https://silo.tips/download/importancia-da-assistencia-e-atenao-farmaceutica-no-ambiente-hospitalar#modals.

Pinto, I. V. L., Castro, M. S., & Reis, A. M. M. (2013) Descrição da atuação do farmacêutico em equipe multiprofissional com ênfase no cuidado ao idoso hospitalizado. Rev. bras. geriatr. Gerontol. 16 (4). https://doi.org/10.1590/S1809-98232013000400009.

Reis, W. C. T., Scopel, C. T., Correr, C. J., & Andrzejevski, V. M. S. (2013). Analysis of clinical pharmacist interventions in a tertiary teaching hospital in Brazil. Einstein. 11(2). https://doi.org/10.1590/S1679-45082013000200010.

Ribeiro, V. F., Sapucaia, K. C. G., Aragão, L. A. O., Bispo, I. C. S., Oliveira, V. F., & Alves, B. L. (2015). Execution of pharmaceutical interventions by An experience in clinical pharmacy. Rev. Bras. Farm. Hosp. Serv. Saúde. 6(4). https://www.rbfhss.org.br/sbrafh/article/view/238.

Silva, E. A., & Macedo, L. C. (2013). Polifarmácia em idosos. Revista Saúde e Pesquisa. 6(3), 77-486. https://periodicos.unicesumar.edu.br/index.php/saudpesq/article/download/2862/2160/.

Silva, L. F., Afonso, T., Sousa, C. V., & Afonso, B. P. D. (2018). Vulnerabilities and rupture risk in the supply of materials and medicine on the supply chain in the Public Hospital. Revista Gestão Da Produção Operações e Sistemas. 13(2). https://doi.org/10.15675/gepros.v13i2.1832.

Downloads

Published

22/10/2022

How to Cite

CARDOSO , D. S. .; BARROS, I. M. da C. .; LISBOA, J. S. .; MATOS, L. E. O.; SANTOS, G. P. . Clinical pharmacist interventions in the identification and prevention of problems related to pharmacotherapy in a tertiary teaching hospital. Research, Society and Development, [S. l.], v. 11, n. 14, p. e153111435760, 2022. DOI: 10.33448/rsd-v11i14.35760. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/35760. Acesso em: 18 apr. 2024.

Issue

Vol. 11 No. 14

Section

Health Sciences

License

Copyright (c) 2022 Damaris Santana Cardoso ; Izadora Menezes da Cunha Barros; Júlia Santana Lisboa; Luiz Eduardo Oliveira Matos; Gilvaneza Piedade Santos

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Authors who publish with this journal agree to the following terms:

1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.