Association between reproductive disorders in pet females (Mammalia) and the development of hydrometra: an integrative literature review

Authors

DOI:

https://doi.org/10.33448/rsd-v11i15.37599

Keywords:

Female; Hydrometrics; Veterinary Medicine; Teriogenology.

Abstract

The estrous cycle is related to the reproduction of a female. However, some diseases directly interfere in the reproductive cycle, an example is the hydrometra, a disease in which occurs the deposition of aseptic and translucent fluid in the lumen of the uterus and that may indirectly interfere in the cyclicity and reproductivity of a female. Given the above, the objective of this integrative review was to identify alterations in organs of the reproductive tract of pet females that favor the development of a hydrometric condition. This is an integrative review of the literature. We selected 14 articles that reported or addressed the theme of hydrometra in pet females (bitches, cats and rabbits). After the selection of the articles, relevant clinical information that may influence the development of hydrometra was extracted. The main conditions related to hydrometra were found in the literature: ectopic location of ureters within the uterus wall and vagina; canine Gartner duct cyst with renal agenesis; urolithiasis; perineal and inguinal hernias; uterine aplasia; remnant ovary syndrome; adenoma and proliferative polyps in the endometrium; teratoma; uterine torsions and adenocarcinoma. Some authors report the importance of control in the use of exogenous progestins since the chronic stimulation of estrogen receptors in the uterine tissue may influence the increased production of intraluminal fluid. Finally, the importance of veterinary monitoring of animals in reproductive age and attitude for early diagnosis of disease and promotion of health and quality of life to females is highlighted.

References

Adams C. E. (1987). The UFAW Handbook on the Care and Management of laboratory animals, 6 th edn. Publisher: Ed T Poole, Avon, Longmanq Scientific and Technical.

Almeida, M. V. D., Rezende, E. P., Lamounier, A. R., Rachid, M. A., Nascimento, E. F., Santos, R. L., & Valle, G. R. (2010). Aplasia segmentar de corpo uterino em cadela sem raça definida: relato de caso. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 62, 797-800. https://doi.org/10.1590/S0102-09352010000400005

Asakawa, M. G., Goldschmidt, M. H., Une, Y., & Nomura, Y. (2008). The immunohistochemical evaluation of estrogen receptor-α and progesterone receptors of normal, hyperplastic, and neoplastic endometrium in 88 pet rabbits. Veterinary Pathology, 45(2), 217-225. https://doi.org/10.1354/vp.45-2-217

Barni, B. D. S., Albuquerque, P. B. D., & Contesini, E. A. (2013). Hiperplasia endometrial cística em cadelas e gatas: revisão de literatura. Ci. Anim., 9-19.

Barroso, J. E. M., da Silva, A. V., Barroso, M. C. M., Silva, G. C., & da Silva, L. A. (2020). Controle Populacional de Cães: uma revisão integrativa. HUMANIDADES E TECNOLOGIA (FINOM), 19(1), 20-34.

Brown, J. L. (2006). Comparative endocrinology of domestic and nondomestic felids. Theriogenology, 66(1), 25-36. https://doi.org/10.1016/j.theriogenology.2006.03.011

Carvalho, A. M. H., Santos, A. D. F., & Silva, C. M. (2020). Indução do estro e métodos para controle das fases do ciclo estral em cadelas. Ciênc. Anim.(Impr.), 117-129.

Chatdarong, K. (2003). Reproductive physiology of the female cat (Vol. 162, No. 162).

Chaves, L. D. C. S., Silva, F. L., de Sousa, J. M. C., de Alencar Oliveira, J. R., da Silva, C. R. A., Holanda, M. S., & Santos, L. P. (2019). Urolitíase e hidrometra em cadela: relato de caso. Pubvet, 14, 128. https://doi.org/10.31533/pubvet.v14n1a494.1-5

Concannon, P. W. (2011). Reproductive cycles of the domestic bitch. Animal reproduction science, 124(3-4), 200-210. https://doi.org/10.1016/j.anireprosci.2010.08.028

Derussi, A. A. P., & Lopes, M. D. (2009). Fisiologia da ovulação, da fertilização e do desenvolvimento embrionário inicial na cadela. Revista Brasileira de Reprodução Animal, 33(4), 231-237.

Ferreira, W. M., Machado, L. C., Jaruche, Y. D. G., Carvalho, G. D., Oliveira, C. D., Souza, J. A. S., & Caríssimo, A. P. G. (2012). Manual prático de cunicultura. Bambuí: Associação Brasileira de Cunicultura.

Fossum, T. W. (2014). Cirurgia de Pequenos Animais. São Paulo: Elsevier, 4ª ed., v. 1, 2014.

Fujita, A., Tsuboi, M., Uchida, K., & Nishimura, R. (2016). Complex malformations of the urogenital tract in a female dog: Gartner duct cyst, ipsilateral renal agenesis, and ipsilateral hydrometra. Japanese Journal of Veterinary Research, 64(2), 147-152.

Hafez, E. S. E., Jainudeen, M. R., & Rosnina, Y. (2004). Hormônios, fatores de crescimento e reprodução. Reprodução animal, 7, 33-53.

Hagman, R. (2017). Aspectos moleculares das doenças uterinas em cadelas. Reprodução em Animais Domésticos, 52, 37-42. https://doi.org/10.1111/rda.13039

Holzlsauer, G. M., de Oliveira, F. A., Martins, L. C. T., Bosso-Holzlsauer, A. C. S., & de Araújo, F. A. P. (2022). Apresentação atípica e resolução cirúrgica de síndrome do ovário remanescente em cadela Terrier brasileiro idosa. Brazilian Journal of Development, 8(4), 30567-30579. https://doi.org/10.34117/bjdv8n4-505

Jaruche, Y. G. (2014). Nota técnica: Ciclo estral das coelhas. Available at: http://acbc.org.br/site/index.php/notas-tecnicas/estral-ciclo. Accessed on: November 03, 2022.

Johnston, S. D., Kustritz, M. V. R., Olson, P. N. S. (2001). Disorders of the canine uterus and uterine tubes (oviducts). In: Johnston, S. D., Kustritz, M. V. R., Olson, P. N. S. Canine and feline theriogenology. Philadelphia: W.B. Saunders, 206-224.

Johnston, S. D., Kustritz, M. V. R., Olson, P. N. S. (2001b). Hydrometra/Mucometra/Hematometra. In: In: Johnston, S. D., Kustritz, M. V. R., Olson, P. N. S. Canine and feline theriogenology. Philadelphia: W.B. Saunders, 206-224.

Kim, M. J., Jo, Y. K., Kang, S. C., Oh, H. J., Kim, G. A., Setyawan, E. M. N., ... & Lee, B. C. (2015). Recovery of In Vivo Matured Oocytes from a Bitch with Hydrometra. Journal of Veterinary Clinics, 32(6), 536-539. https://doi.org/10.17555/jvc.2015.12.32.6.536

Hristov, K., Mehandzhiyski, N., Peev, I., & Georgiev, G. (2017). Case study of hydrometra and uterine adenocarcinoma in a pet rabbit. Med Inform, 3(1), 544-550. https://doi.org/10.18044/Medinform.201741.544

Lapish, J. P. (1985). Hydronephrosis, hydroureter and hydrometra associated with ectopic ureter in a bitch. Journal of Small Animal Practice, 26(10), 613-617. https://doi.org/10.1111/j.1748-5827.1985.tb02187.x

Lockwood, C., Porrit, K., Munn, Z. et al. (2020). Chapter 2: Systematic reviews of qualitative evidence. In: Aromataris, E., Munn, Z. JBI Manual for Evidence Synthesis. https://doi.org/10.46658/JBIRM-17-02

Machado, A. V. P., Lugoch, G., Santos, A. P. I. D., Gonçalves, M. E. P., Oliveira, M. T. D., Vilela, J. A. P., & Beckmann, D. V. (2020). Hérnia perineal em canina fêmea. Acta Scientiae Veterinariae, 48(Suppl 1), 491.

Macun, H. C., & Özyurtlu, N. (2004). Endometrial polyps and adenoma in a cat with hydrometra: case report. Turkish Journal of Veterinary & Animal Sciences, 28(2), 447-449.

Mendes, K. D. S., Silveira, R. C. D. C. P., & Galvão, C. M. (2008). Revisão integrativa: método de pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto & contexto-enfermagem, 17, 758-764. https://doi.org/10.1590/S0104-07072008000400018

Michel, C. (1993). Induction of oestrus in cats by photoperiodic manipulations and social stimuli. Laboratory animals, 27(3), 278-280. https://doi.org/10.1258/002367793780745381

Morales-Salinas, E., Preza-Romero, F., Quintal-Parra, M. D., & García, J. C. (2019). Torsión uterina e hidrometra unilateral en una coneja (Oryctolagus cuniculus) de compañía. Revista Clínica Veterinaria, 5. https://doi.org/10.22201/fmvz.23958766e.201934

Na, S., & Choi, J. (2014). Uterine torsion associated with hydrometra and pyometra in a domestic rabbit. Journal of Veterinary Clinics, 31(6), 544-546. https://doi.org/10.17555/ksvc.2014.12.31.6.544

Nascimento, E. F., Santos, R. L. (2003). Patologia do sistema genital feminino. In: Nascimento, E. F., Santos, R. L. Patologia da reprodução dos animais domésticos. 2.ed. Rio de Janeiro: Guanabara Koogan, 15-89.

Nogueira, C. S., Ferreira, M. H., da Silva, W. C., Silva, L. K. X., Batista, H. R., Araújo, L. J. S., ... & da Silva, É. B. R. (2019). Determinação da fase do ciclo estral através da anamnese e citologia vaginal associada à dosagens hormonais. Brazilian Journal of Animal and Environmental Research, 2(3), 1037-1045.

Oh, K. S., Son, C. H., Kim, B. S., Hwang, S. S., Kim, Y. J., Park, S. J., ... & Cho, K. O. (2005). Segmental aplasia of uterine body in an adult mixed breed dog. Journal of veterinary diagnostic investigation, 17(5), 490-492. https://doi.org/10.1177/104063870501700517

Parker, K., & Snead, E. (2014). Atypical presentation of ovarian remnant syndrome in a dog. Journal of the American Animal Hospital Association, 50(4), e1-e5. https://doi.org/10.5326/JAAHA-MS-6025

Payan-Carreira, R., Pina, J., Costa, M., Seixas, F., & Pires, M. A. (2006). Oestrogen receptors in a case of hydrometra in a bitch. Veterinary record, 158(14), 487. https://doi.org/10.1136/vr.158.14.487

Pereira, L. N. C., de Castro, G. Z. S., Gutjahr, C. A., Bombem, B. D. R., Cruz, M. F. R., Calderon, C., & dos Santos, A. P. M. E. (2022). Achados macroscópicos no sistema reprodutor de cadelas e gatas submetidas a ovariohisterectomia: Relato de experiência. PUBVET, 16, 188. https://doi.org/10.31533/pubvet.v16n05a1102.1-5

Pretzer, S. D. (2008). Clinical presentation of canine pyometra and mucometra: a review. Theriogenology, 70(3), 359-363. https://doi.org/10.1016/j.theriogenology.2008.04.028

Radlinsky, G. A. (2013). Surgery of the Perineum, Rectum Anus. In: Fossum, T.W. Small Animal Surgery. 4th. edn. St. Louis: Elsevier, 1175.

Rautela, R., & Katiyar, R. (2019). Review on canine pyometra, oxidative stress and current trends in diagnostics. Asian Pacific Journal of Reproduction, 8(2), 45. https://doi.org/10.4103/2305-0500.254645

Sabuncu, A., Enginler, S. Ö., Çetin, A. C., Dal, G. E., Bamaç, Ö. E., Yildirim, F., & Yildar, E. (2018). Unilateral Ovarian Mature Teratoma and Hydrometra Case in a Queen. Dicle Üniversitesi Veteriner Fakültesi Dergisi, 11(1), 55-58.

Schlafer, D. H., Miller, R. B. (2007). Female genital system. In: Maxie, M.G. Jubb, Kennedy, and Palmer’s Pathology of Domestic Animals. 4.ed. Philadelphia: Elsevier Saunders, 429-564. https://doi.org/10.1016/B978-070202823-6.50174-3

Schlafer, D. H., Foster, R. A. (2016). Sistema genital feminino. In: Maxie, M.G. Jubb, Kennedy, and Palmer’s Pathology of Domestic Animals, 358. https://doi.org/10.1016/B978-0-7020-5319-1.00015-3

Silva, L. D. M. D. (2020). Considerações sobre a reprodução da gata. Ci. Anim., 57-69.

Silva, L. D. M. D. (2016). Controle do ciclo estral em cadelas. R. bras. Reprod. Anim., 180-187.

Smith, F. O. (2006). Piometra canina. Theriogenology, 66, 3, 610-612. https://doi.org/10.1016/j.theriogenology.2006.04.023

Soares, N. C. S. (2019). Hiperplasia endometrial cística associada a hidrometra felinos: relato de caso. Available at: https://repositorio.ifgoiano.edu.br/handle/prefix/802. Accessed on: November 03, 2022.

Sontas, B. H., Toydemir, F. S., Erdogan, Ö., Şennazli, G., & Ekici, H. (2013). Inguinal herniation with hydrometra/mucometra in a poodle bitch. The Canadian Veterinary Journal, 54(9), 840.

Vermeirsch, H., Van den Broeck, W., Coryn, M., & Simoens, P. (2002). Immunohistochemical detection of androgen receptors in the canine uterus throughout the estrus cycle. Theriogenology, 57(9), 2203-2216. https://doi.org/10.1016/S0093-691X(02)00908-1

Von-Reitzenstein, M., Archbald, L. F., Newell, S. M. (2000). Theriogenology question of the month. Journal of the American Veterinary Medical Association, 2016(8), 1221-1223. https://doi.org/10.2460/javma.2000.216.1221

Voorwald, F. A., Marchi, F. A., Villacis, R. A. R., Alves, C. E. F., Toniollo, G. H., Amorim, R. L., ... & Rogatto, S. R. (2015). Molecular expression profile reveals potential biomarkers and therapeutic targets in canine endometrial lesions. PLoS One, 10(7), e0133894. https://doi.org/10.1371/journal.pone.0133894

Webb, P. (1985). Segmental aplasia and hydrometra in a goat. The Veterinary Record, 117(1), 13-13. https://doi.org/10.1136/vr.117.1.13

Whittemore, R., Chao, A., Jang, M., Minges, K. E., & Park, C. (2014). Methods for knowledge synthesis: an overview. Heart & Lung, 43(5), 453-461. https://doi.org/10.1016/j.hrtlng.2014.05.014

Downloads

Published

20/11/2022

How to Cite

RODRIGUES, H. L. de S. .; BORGES, F. V. .; NAVASQUEZ, L. M. L. .; SOUSA, L. de D. .; OLIVEIRA, V. J. de. Association between reproductive disorders in pet females (Mammalia) and the development of hydrometra: an integrative literature review . Research, Society and Development, [S. l.], v. 11, n. 15, p. e383111537599, 2022. DOI: 10.33448/rsd-v11i15.37599. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/37599. Acesso em: 22 nov. 2024.

Issue

Section

Agrarian and Biological Sciences