Effect of a moisturizing/antiseptic solution of guar gum in tea tree oil in the periorbital region of domestic dogs
DOI:
https://doi.org/10.33448/rsd-v12i1.39548Keywords:
Guar gum; Tea tree; Antisepsis.Abstract
Conjunctivitis cleaners used to remove periorbital cleaners used to remove and remove cleaning products. Usually, chemically modified products are used, seeking their local preference or animal rejection. One of the limiting factors is odor, as this sense is very sharp in dogs. Natural component products are more easily handled by animals and more easily acted upon by natural, microbial and parasitic reduction eye products. We determined the tolerance of domestic animals to a solution of guar gum in tea tree oil, compounded with wide use in humans and animals, with documented safety. We applied the 1% tea tree guar gum solution (Eyepet®) in 30 randomly selected animals, under the supervision of their tutors. All animals had excellent tolerability, without any sign of good local tolerance or systemic toxicity. Although the common sense solution indicated that a solution of guar-melaleuca gum would be well tolerated, our results are relevant to guarantee the safety of the use of this common one for the periorbital asepsis of dogs.
References
Alam, N.H., Meier, R., Rausch, T., Meyer-Wyss, B., Hildebrand, P., Schneider, H., Bachmann, C., Minder, E., Fowler, B., & Gyr, K. (1998). Effects of a partially hydrolyzed guar gum on intestinal absorption of carbohydrate, protein and fat: a double-blind controlled study in volunteers. Clin Nutr. 17(3):125-129.
Alves, E.N. (2003). Red Blood Cell (RBC) – Teste de hemólise: Uma alternativa ao Teste de Draize-Irritação Ocular na avaliação do poder tóxico de produtos cosméticos no Controle de Qualidade./ Tese (Mestrado). INCQS, Programa de Pós-Graduação em Vigilância Sanitária, Rio de Janeiro, 2003. INCQS/ FIOCRUZ, xix. 89p. il. tab. graf.
Carson, C.F., Hammer, K.A., & Riley, T.V. (2006) Melaleuca alternifolia (Tea Tree) oil: a review of antimicrobial and other medicinal properties. Clin Microbiol Rev. 19(1), 50-62.
Castro R. R., Silva, C. M., Nunes, R. M., Cunha, P. L., de Paula, R. C., Feitosa, J. P., Girão, V. C., Pompeu, M. M., Leite, J. A., & Rocha, F. A. (2016). Structural characteristics are crucial to the benefits of guar gum in experimental osteoarthritis. Carbohydrate polymers. 150, 392–399.
Gelatt, K., Gilger, B., & Kern, T. (2013). Vet Ophthalmol. Ames: Wiley-Blackwell.
de Souza Silveira, J., Brasil, C. L., Braga, C. Q., da Silva Moreira, Â., Franz, H. C., Zamboni, R., Sallis, E. S., Albano, A. P., Zambrano, C. G., Araujo, L. C., de Bona da Silva, C., Pötter, L., de Avila Botton, S., & Pereira, D. I. B. (2022). Melaleuca alternifolia formulations in the treatment of experimental pythiosis. Brazilian journal of microbiology. 53(2), 1011–1017.
Hindley, K. E., Groth, A. D., King, M., Graham, K., & Billson, F. M. (2016). Bacterial isolates, antimicrobial susceptibility, and clinical characteristics of bacterial keratitis in dogs presenting to referral practice in Australia. Veterinary ophthalmology. 19(5), 418–426.
Lam, N. S. K., Long, X. X., Griffin, R. C., Chen, M. K., & Doery, J. C. (2018). Can the tea tree oil (Australian native plant: Melaleuca alternifolia Cheel) be an alternative treatment for human demodicosis on skin?. Parasitology. 145(12), 1510–1520.
Mandal, S., Hwang, S., & Shi, S. Q. (2022). Guar gum, a low-cost sustainable biopolymer, for wastewater treatment: A review. International journal of biological macromolecules. 226, 368–382.
Mudgil, D., Barak, S., & Khatkar, B.S. (2014). Guar gum: processing, properties and food applications-A Review. J Food Sci Technol. 51(3), 409-418.
National Toxicology Program. (1982). Carcinogenesis Bioassay of Guar Gum (CAS No. 9000-30-0) in F344 Rats and B6C3F1 Mice (Feed Study). Natl Toxicol Program Tech Rep Ser. 229:111-114.
Pazyar, N., Yaghoobi, R., Bagherani, N., & Kazerouni, A. (2013). A review of applications of tea tree oil in dermatology. International journal of dermatology. 52(7), 784–790.
Sharma, G., Sharma, S., Kumar, A., Al-Muhtaseb, A. H., Naushad, M., Ghfar, A. A., Mola, G. T., & Stadler, F. J. (2018). Guar gum and its composites as potential materials for diverse applications: A review. Carbohydrate polymers, 199, 534–545.
Thombare, N., Jha, U., Mishra, S., & Siddiqui, M. Z. (2016). Guar gum as a promising starting material for diverse applications: A review. International journal of biological macromolecules. 88, 361–372.
Varandas, C., Cartaxeiro, C., Lourenço, A. M., Delgado, E., & Gil, S. (2020). Selected cytokine expression in dogs with alergic conjunctivitis: Correlation with disease activity. Research in veterinary science. 130, 33–40.
Williams, D. L., & Burg, P. (2017). Tear production and intraocular pressure in canine eyes with corneal ulceration. Open veterinary journal. 7(2), 117–125.
Yasin, M., Younis, A., Javed, T., Akram, A., Ahsan, M., Shabbir, R., Ali, M. M., Tahir, A., El-Ballat, E. M., Sheteiwy, M. S., Sammour, R. H., Hano, C., Alhumaydhi, F. A., & El-Esawi, M. A. (2021). River Tea Tree Oil: Composition, Antimicrobial and Antioxidant Activities, and Potential Applications in Agriculture. Plants (Basel, Switzerland). 10(10), 2105.
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., Mortelman, K. (1992). Salmonella Mutagenicity Tests V. Results from the Testing of 311 Chemicals Environ. Molec. Mutagen.19 (21), 2-141.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Rodolfo de Melo Nunes; Virginia Claudia Carneiro Girão Carmona; Ana Carolina Matias Dinelly Pinto; Francisco Airton Castro da Rocha
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
