Association between Helicobacter pylori infection and the risk of developing coronary artery disease: a scoping review
DOI:
https://doi.org/10.33448/rsd-v12i2.39957Keywords:
Helicobacter Pylori; Coronary Disease; Heart.Abstract
Helicobacter Pylori (HP) infection affects billions of people around the world, and this bacterium is considered the most prevalent infectious agent in humans. In recent years, the literature has shown a possible association between this infection and the development of coronary artery disease (CAD), since both conditions are considered chronic diseases, sharing similar pathophysiological events. The present study aims to evaluate the association between HP infection and the risk of developing CAD. For this Scoping Review, carried out through the PubMed and Cochrane Library platforms between 2022 and 2012, the chosen descriptors were ''Helicobacter Pylori'', ''Coronary Disease'' and ''Heart'', associated exclusively with the Boolean operator ''AND''. Inclusion criteria consisted of 1) clinical trials, controlled and randomized tests, reviews and meta-analyses, 2) studies on the association between CAD and PH, 3) studies that evaluated the extent of cardiovascular damage due to PH infection and 4) articles written in Portuguese, Japanese, English or Spanish. Exclusion criteria included inadequacies to the theme, case reports and studies with animals, in addition to texts outside the time limit. The evidence found suggested that the main cardiovascular adverse effects related to HP infection were associated with CAD, atherosclerosis, systemic arterial hypertension and acute myocardial infarction. Screening methods, interventional evaluations and indications for the use of laboratory markers, as well as further clinical analysis of this interaction, remain topics to be better elucidated.
References
Chmiela, M., Gajewski, A., & Rudnicka, K. (2015). Helicobacter pylori vs coronary heart disease-searching for connections. World J. Cardiol., 7(4), 187.
Chung, J., Min, K. W., Son, B. K., Kim, D. H., & Kim, H. L. (2021). Association between histological severity of Helicobacter pylori infection and cardiovascular risk scores in the Korean population. Atherosclerosis, 333, 124-130.
Figura, N., Palazzuoli, A., Vaira, D., Campagna, M., Moretti, E., Iacoponi, F., & Ponzetto, A. (2014). Cross-sectional study: CagA–positive Helicobacter pylori infection, acute coronary artery disease and systemic levels of B-type natriuretic peptide. J. Clin. Pathol., 67(3), 251-257.
Hughes, W. S. (2014). An Hypothesis: The Dramatic Decline in Heart Attacks in the United States is Temporally Related to the Decline in Duodenal Ulcer Disease and Helicobacter pylori Infection. Helicobacter, 19(3), 239-241.
Jamkhande, P. G., Gattani, S. G., & Farhat, S. A. (2016). Helicobacter pylori and cardiovascular complications: a mechanism based review on role of Helicobacter pylori in cardiovascular diseases. Integr Medicine Res., 5(4), 244-249.
Jiang, J., Chen, Y., Shi, J., Song, C., Zhang, J., & Wang, K. (2017). Population attributable burden of Helicobacter pylori-related gastric cancer, coronary heart disease, and ischemic stroke in China. Eur. J. Clin. Microbiol. Infect. Dis., 36(2), 199-212.
Keikha, M., & Karbalaei, M. (2022). Prevalence of antibiotic heteroresistance associated with Helicobacter pylori infection: A systematic review and meta-analysis. Microb. Pathog., 105720.
Kozyrieva, T., Kolesnikova, E., & Shut, I. (2016). Correlation of helicobcter pylori infection with development of cardiovascular risk in patientes with coronary heart disease in association with type 2 diabetes mellitus. Georgian Med. News. (256-257), 24-29
Lin, Y., Obata, Y., Kikuchi, S., Tamakoshi, A., Iso, H., & JACC Study Group. (2015). Helicobacter pylori infection and risk of death from cardiovascular disease among the Japanese population: a nested case-control study within the JACC study. Journal Atheroscler. Thromb., 27987.
Matusiak, A., Chałubiński, M., Broncel, M., Rechciński, T., Rudnicka, K., Miszczyk, E., & Chmiela, M. (2016). Putative consequences of exposure to Helicobacter pylori infection in patients with coronary heart disease in terms of humoral immune response and inflammation. Arch Med Sci., 12(1), 45-54.
Mendes, I. P. G., Fonseca Neto, O. J., Santana, B. V. R. C., Souza, J. L. de, Viana, B. L. A., Correia, R. S., Araujo, H. J. B., Krüger, Y. S., Mendes, Érica de A. S., & Moita, A. N. C. (2022). Cardiomiopatia de Takotsubo como diagnóstico diferencial de síndrome coronariana aguda: diferenças entre os aspectos clínicos. Research, Society and Development, 11(2), e8111225514. https://doi.org/10.33448/rsd-v11i2.25514
Rahmani, Y., Mohammadi, S., Karim, H., Rezazadeh, M., Babanejad, M., Shahmohammadi, A., & Rai, A. (2018). Association of Helicobacter pylori and Coronary heart disease in Iran: A meta-analysis. Med J Islamic Repub Iran, 32, 73.
Rahmani, Y., Mohammadi, S., Rai, A., Zalei, B., & Shahmohammadi, A. (2017). Association of Helicobacter pylori with presence of myocardial infarction in Iran: a systematic review and meta-analysis. Ethiop. J. of Health Sci., 27(4), 433-440.
Riad, M. (2021). Association of Helicobacter pylori infection with coronary artery disease: is it an independent risk factor?. Egypt Heart J., 73(1), 1-6.
Rogha, M., Dadkhah, D., Pourmoghaddas, Z., Shirneshan, K., Nikvarz, M., & Pourmoghaddas, M. (2012). Association of helicobacter pylori infection with severity of coronary heart disease. ARYA Atheroscler, 7(4), 138.
Rogha, M., Nikvarz, M., Pourmoghaddas, Z., Shirneshan, K., Dadkhah, D., & Pourmoghaddas, M. (2012). Is helicobacter pylori infection a risk factor for coronary heart disease? ARYA atheroscler, 8(1), 5.
Sun, J., Rangan, P., Bhat, S. S., & Liu, L. (2016). A Meta‐Analysis of the Association between Helicobacter pylori Infection and Risk of Coronary Heart Disease from Published Prospective Studies. Helicobacter, 21(1), 11-23.
Tali, L. D. N., Faujo, G. F. N., Konang, J. L. N., Dzoyem, J. P., & Kouitcheu, L. B. M. (2022). Relationship between active Helicobacter pylori infection and risk factors of cardiovascular diseases, a cross-sectional hospital-based study in a Sub-Saharan setting. BMC Infect. Dis., 22(1), 1-21.
Tang, B. W., Wang, X. M., & Wu, J. (2020). Progress in research on the relationship between Helicobacter pylori infection and cardiovascular diseases and its risk factors. Zhonghua yu fang yi xue za zhi [Chin J Prev Med.], 54(3), 327-331.
Teixeira, T. F., de Souza, I. K. F., & Rocha, R. D. R. (2016). Helicobacter pylori: infecção, diagnóstico laboratorial e tratamento. Percurso Acad., 6(12), 481-504.
Tong, L., Wang, B. B., Li, F. H., Lv, S. P., Pan, F. F., & Dong, X. J. (2022). An Updated Meta-Analysis of the Relationship Between Helicobacter pylori Infection and the Risk of Coronary Heart Disease. Front Cardiovasc Med., 9.
Wang, X., Du, M., & Li, F. (2022). Clinical Observation of Helicobacter pylori Infection and Risk Factors and Cytotoxin-Associated Protein A in Patients with Coronary Heart Disease. Contrast Media Mol Imaging, 2022.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Trinnye Luizze Santos; Walquiria da Silva Pedra Parreira; Ricardo Ferreira Roman; Gustavo Brustollin; Carlos Eduardo Martins Alves; Ruanner Ronann Marques Durães; Ariane Matoso da Silva; Lucas França Belfort Pereira; Maiko Rodrigo Fetzer; Luciano da Silva Alves
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
