Flaxseed oil supplementation in patients on chronic hemodialysis: an analysis of anthropometric and biochemical variables

Authors

DOI:

https://doi.org/10.33448/rsd-v9i7.4081

Keywords:

Nutritional status; Functional foods; Dialysis.

Abstract

Chronic hemodialysis patients have a nutritional deficit and an inflammatory state that contribute exponentially to the morbidity and mortality of these patients. From then on, the objective was to evaluate the effects of supplementation with flaxseed oil on the nutritional and inflammatory status of patients on chronic hemodialysis in the city of Patos, Paraíba. The research is a prospective longitudinal study, of an interventional clinical type, involving 28 adult patients of both genders undergoing chronic hemodialysis. The patients were randomly divided into two groups: Control Group (CG) and Experimental Group (GE), received mineral oil and flaxseed oil, respectively, both in the proportion of 5 mL daily for the period of 60 days. Anthropometric and biochemical data were collected. The results obtained showed that the values of lymphocytes, monocytes as well as potassium, ferritin, tranferrine, creatinine, previously increased, after supplementation with linseed oil, reached the values considered normal, for women. It is suggested an evaluation in larger quantities and for a longer time to evaluate results.

References

Alvarenga, L. D. A., Andrade, B. D., Moreira, M. A., Nascimento, R. D. P., Macedo, I. D., & Aguiar, A. S. D. (2017). Análise do perfil nutricional de pacientes renais crônicos em hemodiálise em relação ao tempo de tratamento. Brazilian Journal of Nephrology, 39(3), 283-286.

Amorim, R. G., Guedes, G. D. S., Vasconcelos, S. M. D. L., & Santos, J. C. D. F. (2019). Doença Renal do Diabetes: Cross-Linking entre Hiperglicemia, Desequilíbrio Redox e Inflamação. Arquivos Brasileiros de Cardiologia, 112(5), 577-587.

Anand, N., Chandrasekaran, S. C., & Alam, M. N. (2013). The malnutrition inflammation complex syndrome-the micsing factor in the perio-chronic kidney disease interlink. Journal of clinical and diagnostic research: JCDR, 7(4), 763.

Ashwell, M., & Gibson, S. (2016). Waist-to-height ratio as an indicator of ‘early health risk’: simpler and more predictive than using a ‘matrix’based on BMI and waist circumference. BMJ open, 6(3), e010159.

Corrêa, M. M., Facchini, L. A., Thumé, E., Oliveira, E. R. A. D., & Tomasi, E. (2019). Habilidade da razão cintura-estatura na identificação de risco à saúde. Revista de Saúde Pública, 53, 66.

Dino, B. D., & Campos, R. (2018). Insuficiência renal crônica e suas implicações para os sistemas metabólicos. revista uniandrade, 18(3), 149-156.

Faulkner, J. A. (1968). Physiology of swimming and diving. In: Falls H. Exercise physiology. Baltimore. Academic Press.

Fernandes, K. H. A., & Muttoni, S. M. P. (2016). Influência do uso de diferentes métodos antropométricos na avaliação do diagnóstico nutricional de pacientes em programa de hemodiálise. Rev Bras Nutr Clin, 31(1), 43-8.

Food and Agriculture Organization. FAO/WHO/UNU. (2001). Human energy requirements. Report of a joint FAO/WHO/UNU expert consultation. Rome: Food and Agriculture Organization.

Frisancho, A. R. (1993). Anthropometry standard for the assessment of growth and nutritional status. Michigan: The University of Michigan Press, 84(1), 104-105.

Fruehwirth, M., Folha, R. D. A., Pereira, F. M., & Delai, R. M. (2018). Efeitos da ingestão de semente de linhaça e seu possivel efeito hipocolesterolêmico. Nutrición clínica y dietética hospitalaria, 38(1), 128-134.

Hashempur, M. H., Homayouni, K., Ashraf, A., Salehi, A., Taghizadeh, M., & Heydari, M. (2014). Effect of Linum usitatissimum L.(linseed) oil on mild and moderate carpal tunnel syndrome: a randomized, double-blind, placebo-controlled clinical trial. DARU Journal of Pharmaceutical Sciences, 22(1), 43.

Junior, W. S. L., Saraiva, I. C., Caldas, D. R. C., de Jesus Silva, A. L., & Barbosa, A. M. (2019). Estado Nutricional e Níveis Séricos de Minerais em Pacientes com Insuficiência Renal em Hemodiálise/Nutritional Status and Serum Mineral Levels in Patients with Renal Insufficiency in Hemodiálise. Saúde em Foco, 6(2), 40-51.

Kaithwas, G., & Majumdar, D. K. (2013). Effect of L. usitatissimum (flaxseed/linseed) fixed oil against distinct phases of inflammation. ISRN inflammation.

Pereira, AS et al. (2018). Metodologia da pesquisa científica. [e-book]. Santa Maria. Ed. UAB/NTE/UFSM. Acesso em: 11 maio 2020. Disponível em: https://repositorio.ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Cientifica.pdf?sequence=1.

Riella MC, & Martins C (2013). Nutrição e o Rim. 2.ed. Rio de Janeiro: Guanabara.

Stenvinkel, P., Gillespie, I. A., Tunks, J., Addison, J., Kronenberg, F., Drueke, T. B., ... & Froissart, M. (2016). Inflammation modifies the paradoxical association between body mass index and mortality in hemodialysis patients. Journal of the American Society of Nephrology, 27(5), 1479-1486.

Thomé, FS, Sesso, RC, Lopes, AA, Lugon, JR & Martins, CT. (2019). Inquérito brasileiro de diálise crônica 2017. Brazilian Journal of Nephrology, 41(2), 208-214.

Volp, ACP, Alfenas, RDCG, Costa, NMB, Minim, VPR, Stringueta, P, & Bressan, J. (2008). Capacidade dos biomarcadores inflamatórios em predizer a síndrome metabólica: Inflammation biomarkers capacity in predicting the metabolic syndrome. Arquivos Brasileiros de Endocrinologia & Metabologia, 52(3), 537-549.

Published

12/05/2020

How to Cite

SILVA, A. A. P. e; SOUSA, F. H. G.; PONTES, E. D. S.; SILVA, J. Y. P. da; SANTOS, N. M.; DONATO, N. R. Flaxseed oil supplementation in patients on chronic hemodialysis: an analysis of anthropometric and biochemical variables. Research, Society and Development, [S. l.], v. 9, n. 7, p. e302974081, 2020. DOI: 10.33448/rsd-v9i7.4081. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/4081. Acesso em: 22 dec. 2024.

Issue

Section

Health Sciences