Comparison of Efficacy of Unna’s boot and Ozone therapy on Chronic Venous Leg Ulcers: a series of case

Authors

DOI:

https://doi.org/10.33448/rsd-v9i9.6967

Keywords:

Venous leg ulcers; Unna’s boot; Ozone therapy.

Abstract

The aim of this study was to evaluate and compare the effectiveness of Unna’s boot and ozone therapy on chronic venous leg ulcers. Seven patients with chronic venous leg ulcers were taken into the study and were randomly divided into two groups: Unna’s boot treatment group (BU); Ozone treatment group (OZ). The therapies were performed weekly until wound closure. The morphological descriptive results demonstrated that during the treatments, it was possible to observe the presence of semi-planar borders, granulation tissue, reduction of edema, fibrin and exudate and absence of odor. These morphological modifications were more pronounced in the OZ when compared to the BU. Furthermore, both treatments promoted the same wound healing time, never the less the ozone therapy produced a higher percentage of weekly wound reduction compared to Unna's boot. Unna's boot and ozone therapy treatments appeared to positively impact the course of wound healing in chronic wounds, however the ozone therapy may improve the healing of chronic venous leg ulcers in a higher weekly percentage.

Author Biography

Lívia Assis, Universidade Brasil

Professor de Engenharia Biomédica, Universidade Brasil, São Paulo, SP, Brasil

References

Abreu, A. M., Oliveira, B. R. B., & Manarte, J. J. (2013). Treatment of venous ulcers with an unna boot: a case study. Online Braz J Nurs. 12 (1), 198-208. Retrieved from http://www.objnursing. uff.br/index.php/nursing/article/viewFile/3845/pdf_1

Boateng, J., & Catanzano, O. (2015). Advanced Therapeutic Dressings for Effective Wound Healing--A Review. Journal of pharmaceutical sciences, 104(11), 3653–3680. Ht

Borges, E. L., Ferraz, A. F., Carvalho, D. V., Matos, S. S., & Lima, V. L. A. N. (2016). Prevention of varicose ulcer relapse: a cohort study. Acta Paul Enferm. 29(1):9-16. Retrieved from: http://www.scielo.br/pdf/ape/v29n1/en_1982-0194- ape-29-01-0009.pdf

Botelho, L. S., Arboit, E. L., & Freitag, V. L. (2020). Nurses' performance in the care of the prevention and treatment of pressure injuries. Research, Society and Development. 9(7),1-19, e775974644

Souza, E. M., Yoshida, W. B., Melo, V. A., Aragão, J. A., & Oliveira, L. A. (2013). Ulcer due to chronic venous disease: a sociodemographic study in northeastern Brazil. Annals of vascular surgery, 27(5), 571–576. https://doi.org/10.1016/j.avsg.2012.07.021

Eberhardt, R. T., & Raffetto, J. D. (2014). Chronic venous insufficiency. Circulation, 130(4), 333–346. https://doi.org/10.1161/CIRCULATIONAHA.113.006898

Harrison, M. B., Graham, I. D., Friedberg, E., Lorimer, K., & Vandevelde-Coke, S. (2001). Regional planning study. Assessing the population with leg and foot ulcers. The Canadian nurse, 97(2), 18–23

Izadi, M., Kheirjou, R., Mohammadpour, R., Aliyoldashi, M. H., Moghadam, S. J., Khorvash, F., Jafari, N. J., Shirvani, S., & Khalili, N. (2019). Efficacy of comprehensive ozone therapy in diabetic foot ulcer healing. Diabetes & metabolic syndrome, 13(1), 822–825. https://doi.org/10.1016/j.dsx.2018.11.060

Kelechi, T. J., Johnson, J. J., & Yates, S. (2015). Chronic venous disease and venous leg ulcers: An evidence-based update. Journal of vascular nursing: official publication of the Society for Peripheral Vascular Nursing, 33(2), 36–46. https://doi.org/10.1016/j.jvn.2015.01.003

Kim, H. S., Noh, S. U., Han, Y. W., Kim, K. M., Kang, H., Kim, H. O., & Park, Y. M. (2009). Therapeutic effects of topical application of ozone on acute cutaneous wound healing. Journal of Korean medical science, 24(3), 368–374. https://doi.org/10.3346/jkms.2009.24.3.368

Lal B. K. (2015). Venous ulcers of the lower extremity: Definition, epidemiology, and economic and social burdens. Seminars in vascular surgery, 28(1), 3–5. https://doi.org/10.1053/j.semvascsurg.2015.05.002

Mosti, G. (2016). Compression in leg ulcer treatment:in elastic compression. Phlebol. 29 (1suppl):146-52. Retrieved from http://phl.sagepub.com/content/29/1_suppl/146.long

O'Meara, S., Al-Kurdi, D., Ologun, Y., Ovington, L. G., Martyn-St James, M., & Richardson, R. (2014). Antibiotics and antiseptics for venous leg ulcers. The Cochrane database of systematic reviews, (1), CD003557. https://doi.org/10.1002/14651858.CD003557.pub5

Patel, P. V., Kumar, V., Kumar, S., G. V., & Patel, A. (2011). Therapeutic effect of topical ozonated oil on the epithelial healing of palatal wound sites: a planimetrical and cytological study. Journal of investigative and clinical dentistry, 2(4), 248–258. https://doi.org/10.1111/j.2041-1626.2011.00072.x

Pereira, A. S., et al. (2018). Metodologia da pesquisa científica. [e-book]. Santa Maria. Ed. UAB/NTE/UFSM. Retrieved from https://repositorio.ufsm.br/bitstream/ handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Cientifica.pdf?sequence=1.

Phillips, P., Lumley, E., Duncan, R., Aber, A., Woods, H. B., Jones, G. L., & Michaels, J. (2018). A systematic review of qualitative research into people's experiences of living with venous leg ulcers. Journal of advanced nursing, 74(3), 550–563. https://doi.org/10.1111/jan.13465

Rosul, M. V., & Patskan, B. M. (2016). Ozone therapy effectiveness in patients with ulcerous lesions due to diabetes mellitus. Wiadomosci lekarskie (Warsaw, Poland : 1960), 69(1), 7–9.

Sagai, M., & Bocci, V. (2011). Mechanisms of Action Involved in Ozone Therapy: Is healing induced via a mild oxidative stress?. Medical gas research, 1, 29. https://doi.org/10.1186/2045-9912-1-29

Salome, G. M., de Brito, M. J., & Ferreira, L. M. (2014). Impact of compression therapy using Unna's boot on the self-esteem of patients with venous leg ulcers. Journal of wound care, 23(9), 442–446. https://doi.org/10.12968/jowc.2014.23.9.442

Scotton, M. F., Miot, H. A., & Abbade, L. P. (2014). Factors that influence healing of chronic venous leg ulcers: a retrospective cohort. Anais brasileiros de dermatologia, 89(3), 414–422. https://doi.org/10.1590/abd1806-4841.20142687

Silva, M. H., Jesus, M. C., Oliveira, D. M., & Merighi, M. A. (2017). Unna's boot: experience of care of people with venous ulcers. Revista brasileira de enfermagem, 70(2), 349–356. https://doi.org/10.1590/0034-7167-2016-021

Soares, C. D., Morais, T., Araújo, R., Meyer, P. F., Oliveira, E., Silva, R., Carreiro, E. M., Carreiro, E. P., Belloco, V. G., Mariz, B., & Jorge-Junior, J. (2019). Effects of subcutaneous injection of ozone during wound healing in rats. Growth factors (Chur, Switzerland), 37(1-2), 95–103. https://doi.org/10.1080/08977194.2019.1643339

Zhang, J., Guan, M., Xie, C., Luo, X., Zhang, Q., & Xue, Y. (2014). Increased growth factors play a role in wound healing promoted by noninvasive oxygen-ozone therapy in diabetic patients with foot ulcers. Oxidative medicine and cellular longevity, 2014, 273475. https://doi.org/10.1155/2014/273475

Published

11/08/2020

How to Cite

CASTILO, D. V. F. D.; AMARAL, M. M.; TIM, C. R.; MARTIGNAGO, C. C. S.; MACEDO, D. B.; BASTOS, D. D. C.; ASSIS, L. . Comparison of Efficacy of Unna’s boot and Ozone therapy on Chronic Venous Leg Ulcers: a series of case. Research, Society and Development, [S. l.], v. 9, n. 9, p. e44996967, 2020. DOI: 10.33448/rsd-v9i9.6967. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/6967. Acesso em: 25 nov. 2024.

Issue

Section

Health Sciences