Smoking as a triggering factor for alzheimer's disease: an integrative review
DOI:
https://doi.org/10.33448/rsd-v9i11.9971Keywords:
Dementia; Alzheimer disease’s; Medicine; Neurology; Tobacco products.Abstract
More than 50 million people worldwide suffer from dementia, with Alzheimer's being the most common, especially in smokers. The objective was to identify studies that related smoking to Alzheimer's. The methodology was an integrative literature review to respond to the PICO strategy (P: smokers; I: cigarette; C: non-cigarette users; O: cigarette as a triggering factor for Alzheimer's Disease): Smoking can be a triggering factor of Alzheimer's? The results showed smoking as a risk factor for the disease, in addition to chronic, recreational or passive smoking being associated with increased cerebral oxidative stress. Heavy consumption in middle age increased the risk of dementia by more than 100% compared to non-smokers. Thus, it is important to have measures and policies that guide about the risks and the reduction of cigarette consumption, contributing to greater development and quality of life for the population.
References
Cayton, H., Graham, N. & Warner, J. (2016). Tudo Sobre Doença de Alzheimer. São Paulo: Andrei.
Cummings, J. L. & Back, C (1998). The cholinergic hypothesis of neuropsychiatric symptoms in alzheimer disease. American Journal of Geriatric Psychiatry. 6(2), 64-78. DOI: http://dx.doi.org/10.1097/00019442-199821001-00009
Dreagan, A., Stewart, R. & Guilliford, M. C. (2013) Cardiovascular risk factors and cognitive decline in adults aged 50 and over: a population-based cohort study. Age Aging. 42(3), 338-45. DOI: http://dx.doi.org/10.1093/ageing/afs166
Durazzo, T. C., Korecka, M., Trojanowski, J. Q., Weiner, M. W., O’Hara, R., Ashford, J. W. et al. (2016). Active Cigarette Smoking in Cognitively-Normal Elders and Probable Alz-heimer’s Disease is Associated with Elevated Cerebrospinal Fluid Oxidative Stress Bi-omarkers. Journal of Alzheimer’s Disease. 54(1), 99-107. DOI: http://dx.doi.org/10.3233/JAD-160413
Durazzo, T. C., Mattsson, N. & Weiner, M. W. (2014). Smoking and increased Alzheimer’s disease risk: A review of potential mechanisms. Alzheimers Dementia. 10(Suppl 3), S122-45. DOI: http://dx.doi.org/10.1016/j.jalz.2014.04.009
Durazzo, T. C., Meyerhoff, D. J. & Yoder, K. K. (2018). Cigarette smoking is associated with cortical thinning in anterior frontal regions, insula and regions showing atrophy in early Alz-heimer’s Disease. Drug and Alcohol Dependence. 192, 277-84. DOI: http://dx.doi.org/10.1016/j.drugalcdep.2018.08.009
Engelhardt, E., Tocquer, C., André, C., Moreira, D. M., Okamoto, I. H. & Cavalcanti, J. L. S. (2011). Demência Vascular: Critérios diagnósticos e exames complementares. Dementia Neu-ropsychol. 5(Suppl 1), 49-77.
Federal University of São Paulo (2014). Brazilian Center for Information on Psychotropic Drugs [Internet]. [cited in 2020 Nov. 5]. Available at: https://www.cebrid.com.br/livreto-informativo-sobre-drogas/
Köche, J. C. (2011). Fundamentos de metodologia científica: teoria da ciência e iniciação à pesquisa (Edição digital). Petrópolis, RJ. Vozes.
Ministério da Saúde (2014). Diretrizes metodológicas: Sistema GRADE – manual de gradua-ção da qualidade da evidência e força de recomendação para tomada de decisão em saúde (1a Ed). Departamento de Ciência e Tecnologia. Brasília, DF. Ministério da Saúde.
Ministério da Saúde (2018). O que é Alzheimer? Vigilância Epidemiológica e Sanitária. Bra-sília, DF. Ministério da Saúde.
Pereira, A. S., Shitsuka, D. M., Parreira, F. J. & Shitsuka, R. (2018). Metodologia da pesquisa científica (1a Ed). Núcleo de Tecnologia Educacional. Santa Maria, RS. UFSM.
Querfurth, H. W. & LaFerla, F. M. (2010). Alzheimer’s Disease. New England Journal Medi-cal. 362(4), 329-44. DOI: http://dx.doi.org/10.1056/NEJMra0909142
Rusanen, M., Kivipelto, M., Quesenberry Jr. C. P., Zhou, J. & Whitmer, R.A. (2011). Heavy smoking in midlife and long-term risk of Alzheimer disease and vascular dementia. Archives of Internal Medicine.171(4), 333-9. DOI : http://dx.doi.org/10.1001/archinternmed.2010.393
Souza, M. T., Silva, M. D. & Carvalho, R. (2010). Revisão integrativa: o que é e como fazer. Einstein. 8 (1 Pt 1), 102-6. DOI: https://doi.org/10.1590/s1679-45082010rw1134
Toda, N. & Okamura, T. (2016). Cigarette smoking impairs nitric oxide-mediated cerebral blood flow increase: Implications for Alzheimer's disease. Journal of Pharmacological Sci-ences. 131(Issue 4), 223-32. DOI: http://dx.doi.org/10.1016/j.jphs.2016.07.001
Wallin, C., Sholts, S. B., Österlund, N., Luo, J., Jarvet, J., Roos, P. M. et al. (2017) Alzheimer’s disease and cigarette smoke components: effects of nicotine, PAHs, and Cd(II), Cr(III), Pb(II), Pb(IV) ions on amyloid-β peptide aggregation. Scientific Reports. 7:14423. DOI: http://dx.doi.org/10.1038/s41598-017-13759-5
World Health Organization (2019). Mental Health Home [Internet]. 2019. [cited in 2020 Nov. 5]. Available at: https://www.who.int/news-room/fact-sheets/detail/dementia
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Copyright (c) 2020 Caio Felipe Thomazin Panicio; Higor Maluta; Fernando Lima Salata; Renan Roéffero Brambilla; Angélica Augusta Grigoli Dominato
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