Contenido total de fenoles y actividades antioxidantes y anticolinesterasas de plantas medicinales en el Parque Estatal Cocó (Fortaleza-CE, Brasil)
DOI:
https://doi.org/10.33448/rsd-v10i5.14493Palabras clave:
Parque Estatal Cocó; Plantas medicinales; Actividad antioxidante; Actividad anticolinesterasa.Resumen
El Parque Cocó del Estado en la ciudad de Fortaleza-CE presenta principalmente una flora de manglar e incluye plantas paisajísticas y medicinales. El objetivo de este estudio es determinar el contenido total de fenol, la actividad antioxidante frente al radical libre DPPH y la inhibición de la enzima acetilcolinesterasa (AChE) en extractos etanólicos de 30 especies medicinales y así evaluar qué plantas tienen potencial contra la enfermedad de Alzheimer. Las plantas ricas en compuestos fenólicos con cantidades que van desde 297.46 ± 26.94 a 599.30 ± 17.08 mg GAE/g de extracto vegetal, que mostraron mayor actividad antioxidante (con IC50 contra el radical DPPH de 3.44 ± 0.16 a 3.73 ± 0.12 µg mL-1) y superiores El poder inhibidor de la acetilcolinesterasa (IC50 < 20 μg mL-1) fueron Anacardium occidentale, Ceiba pentandra, Lagucularia racemosa, Mangifera indica, Myracrodrum urundeuva y Terminalia catappa. Luego, estas especies y sus constituyentes se recomiendan para estudios más específicos relacionados con la enfermedad de Alzheimer.
Citas
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