Análisis de pH y actividad antimicrobiana de un nuevo fármaco intracanal biocerámico Bio-C Temp

Autores/as

DOI:

https://doi.org/10.33448/rsd-v10i7.16550

Palabras clave:

Hidróxido de calcio; Silicato de cálcio; Enterococcus faecalis; Acción antimicrobiana.

Resumen

Los medicamentos intracanal con actividad antimicrobiana son importantes como adyuvantes en la desinfección del sistema de conductos radiculares. Por lo tanto, este estudio evaluó, in vitro, el pH y la actividad antimicrobiana de un nuevo medicamento intracanal biocerámico (Bio-C Temp) en comparación con medicamentos de hidróxido de calcio (HC). La determinación del pH se realizó mediante un medidor de pH en los periodos de 30 minutos, 3, 24, 72 y 168 horas. Los medicamentos Ultracal®XS, hidróxido de calcio con suero (HC/suero), hidróxido de calcio con propilenglicol (HC/PG) y Bio-C Temp (biocerámica) se probaron contra biopelículas de dos cepas de Enterococcus faecalis (ATCC 29212 y 4083) utilizando pruebas de contacto directo (TCD) y de membrana restringida (TRM). La supervivencia bacteriana se determinó contando las unidades formadoras de colonias (UFCs) y los datos se compararon estadísticamente (P < 0,05). La pasta Bio-C Temp tuvo el valor de pH más bajo en los tiempos evaluados. Los grupos HC/Soro y HC/PG mostraron una mayor acción en comparación con el control en el TCD (P < 0.05) contra las dos cepas probadas. Además, HC/PG mostró una mayor actividad antibacteriana que Bio-C Temp (P < 0,05). Todos los grupos mostraron una diferencia en comparación con el grupo de control en el TRM contra la cepa 29212, y solo HC/PG mostró una diferencia significativa en comparación con el control contra las biopelículas de la cepa 4083. Bio-C Temp mostró una acción antibacteriana similar a Ultracal®XS, sin embargo mostró menor acción en relación a HC/PG. La pasta de hidróxido de calcio asociada con propilenglicol mostró ventajas sobre las otras probadas.

Citas

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Publicado

23/06/2021

Cómo citar

VIANA, F. L. P.; SAMPIERI, M. B. da S. .; VIANA, P. P.; CRUZ, S. M. L.; VIVAN, R. R. .; DUARTE, M. A. H.; ZANIN, I. C. J.; VASCONCELOS, B. C. de. Análisis de pH y actividad antimicrobiana de un nuevo fármaco intracanal biocerámico Bio-C Temp . Research, Society and Development, [S. l.], v. 10, n. 7, p. e33310716550, 2021. DOI: 10.33448/rsd-v10i7.16550. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/16550. Acesso em: 28 nov. 2024.

Número

Sección

Ciencias de la salud