Quality of life of people with HIV/hepatitis C coinfection: a systematic review

Authors

DOI:

https://doi.org/10.33448/rsd-v10i10.18162

Keywords:

Quality of Life; HIV; Hepatitis C; Coinfecção.

Abstract

Objective: To describe the quality of life of people with HIV/hepatitis C coinfection. Method: Systematic review guided by the question "How is the quality of life of people living with HIV//hepatitis C coinfection?" The PECO strategy was used to select descriptors in Portuguese, English, and Spanish, allowing the bibliographic search in April 2021 in the Embase, Scopus, PubMed, CINAHL, Academic Search Premier, SocINDEX, and LILACS databases without limitation of period of publication. Two independent reviewers performed study selection and data extraction. Results: A total of 1,536 publications were identified, of which 14 were included in this review. It was identified that people with HIV//hepatitis C coinfection have several domains with impaired quality of life, which is worse when compared to the general population without morbidities and people with  HIV or hepatitis C monoinfection. It was also identified that the treatment for hepatitis C in people with coinfection has a positive impact on quality of life, especially in patients with a sustained virological response and in treatments free of interferon and ribavirin. Conclusion: The study showed that people with HIV/hepatitis C coinfection have impaired quality of life in aspects ranging from physical to social domains. Therefore, the approach to the quality of life of these people shall be implemented in health services to contribute to the redefinition of living with two chronic diseases and to reorient care towards the most affected aspects in these people.

References

Braitstein, P., Montessori, V., Chan, K., Montaner, J. S. G., Schechter, M. T., O’Shaughnessy, M. V., & Hogg, R. S. (2005). Quality of life, depression and fatigue among persons co-infected with HIV and hepatitis C: outcomes from a population-based cohort. AIDS Care, 17(4), 505-515. doi: 10.1080/09540120412331291733

Brazier, J., Jones, N., & Kind, P. (1993). Testing the validity of the Euroqol and comparing it with the SF-36 health survey questionnaire. Quality of Life Research, 2(3), 169-180. doi: 10.1007/BF00435221

Costa, T. L. da, Oliveira, D. C. de, & Formozo, G. A. (2015). The health sector in social representations of HIV/Aids and quality of life of seropositive people. Escola Anna Nery - Revista de Enfermagem, 19(3),475-483. doi: 10.5935/1414-8145.20150063

Donato, H., & Donato, M. (2019). Etapas na Condução de uma Revisão Sistemática. Acta Médica Portuguesa, 32(3), 227-235. doi: 10.20344/amp.11923

Fleck, M. P. de A. (2000). O instrumento de avaliação de qualidade de vida da Organização Mundial da Saúde (WHOQOL-100): características e perspectivas. Ciência & Saúde Coletiva, 5(1), 33-38. doi: 10.1590/S1413-81232000000100004

Fleming, C. A., Christiansen, D., Nunes, D., Heeren, T., Thornton, D., Horsburgh, Jr. , C. R., James Koziel, M., Graham, C., & Craven, D. E. (2004). Health‐Related Quality of Life of Patients with HIV Disease: Impact of Hepatitis C Coinfection. Clinical Infectious Diseases, 38(4): 572-578. doi: 10.1086/381263

Gillis, J., Cooper, C., Rourke, S., Rueda, S., O’Brien, K., Collins, E., Rachlis, A., Hart, T. A., & Raboud, J. (2013). Impact of hepatitis B and C co-infection on health-related quality of life in HIV positive individuals. Quality of Life Research, 22(7), 1525-1535. doi: 10.1007/s11136-012-0283-7

Heffernan, A., Barber, E., Cook, N. A., Gomaa, A. I., Harley, Y. X., Jones, C. R., Lim, A. G., Mohamed, Z., Nayagam, S., Ndow, G., Shah, R., Sonderup, M. W., Spearman, C. W., Waked, I., Wilkinson, R. J., & Taylor-Robinson, S. D. (2018). Aiming at the global elimination of Viral Hepatitis: challenges along the care continuum. Open Forum Infectious Diseases, 5(1), ofx252. doi: 10.1093/ofid/ofx252

Kanwal, F., Gralnek, I. M., Hays, R. D., Dulai, G. S., Spiegel, B. M. R., Bozzette, S., & Asch, S. (2005). Impact of chronic viral hepatitis on health-related quality of life in HIV: results from a nationally representative sample. The American Journal of Gastroenterology, 100(9), 1984-1994. doi: 10.1111/j.1572-0241.2005.41962.x

Kauhl, B., Heil, J., Hoebe, C. J. P. A., Schweikart, J., Krafft, T., & Dukers-Muijrers, N. H. T. M. (2015). The spatial distribution of Hepatitis C Virus Infections and associated determinants—an application of a geographically weighted poisson regression for evidence-based screening interventions in hotspots. PLOS ONE, 10(9), e0135656. doi: 10.1371/journal.pone.0135656

Kemmer, N., Hua, L., Andersen, J. W., Chung, R. T., Butt, A. A., & Sherman, K. E. (2012). Health-related quality of life in subjects with HCV/HIV coinfection: results from ACTG 5178 study. Journal of Viral Hepatitis, 19(11), 792-800. doi: 10.1111/j.1365-2893.2012.01609.x

Marcellin, F., Préau, M., Ravaux, I., Dellamonica, P., Spire, B., & Carrieri, M. P. (2007). Self-reported fatigue and depressive symptoms as main indicators of the quality of life (QOL) of patients living with HIV and Hepatitis C: implications for clinical management and future research. HIV Clinical Trials, 8(5), 320-327. doi: 10.1310/hct0805-320

Marcellin, F., Protopopescu, C., Esterle, L., Wittkop, L., Piroth, L., Aumaitre, H., Bouchaud, O., Goujard, C., Vittecoq, D., Dabis, F., Salmon-Ceron, D., Spire, B., Roux, P., & Carrieri, M. P. (2017). Anger and quality of life in patients co-infected with HIV and hepatitis C virus: a cross-sectional study (ANRS CO13-HEPAVIH). European Journal of Gastroenterology & Hepatology, 29(7), 786-791. doi: 10.1097/MEG.0000000000000883

Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., Altman, D., Antes, G., Atkins, D., Barbour, V., Barrowman, N., Berlin, J. A., Clark, J., Clarke, M., Cook, D., D’Amico, R., Deeks, J. J., Devereaux, P. J., Dickersin, K., Egger, M., Ernst, E., … Tugwell, P. (2009). Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. PLoS Medicine, 6(7), e1000097. doi: 10.1371/journal.pmed.1000097

Moola, S., Munn, Z., Sears, K., Sfetcu, R., Currie, M., Lisy, K., Tufanaru, C., Qureshi, R., Mattis, P., & Mu, P. (2015). Conducting systematic reviews of association (etiology). International Journal of Evidence-Based Healthcare, 13(3), 163-169. doi: 10.1097/XEB.0000000000000064

Moola, S., Munn, Z., Tufanaru, C., Aromataris, E., Sears, K., Sfetc, R., Currie, M., Lisy, K., Qureshi, R., Mattis, P., & Mu, P.-F. (2020). Chapter 7: Systematic reviews of etiology and risk. In JBI Manual for Evidence Synthesis. Joanna Briggs Institute. doi: 10.46658/JBIMES-20-08

Ouzzani, M., Hammady, H., Fedorowicz, Z., & Elmagarmid, A. (2016). Rayyan—a web and mobile app for systematic reviews. Systematic Reviews, 5(1), 210. doi: 10.1186/s13643-016-0384-4

Pereira, M., & Fialho, R. (2016). Assessment of factors associated with the quality of life of patients living with HIV/HCV co-infection. Journal of Behavioral Medicine, 39(5), 767-781. doi: 10.1007/s10865-016-9778-y

Platt, L., Easterbrook, P., Gower, E., McDonald, B., Sabin, K., McGowan, C., Yanny, I., Razavi, H., & Vickerman, P. (2016). Prevalence and burden of HCV co-infection in people living with HIV: a global systematic review and meta-analysis. The Lancet Infectious Diseases, 16(7), 797-808. doi: 10.1016/S1473-3099(15)00485-5

Sabouri, S., Delavar, A., & Jabbari, H. (2016). Quality of life among human immunodeficiency virus-1 infected and human immunodeficiency virus-1/hepatitis C virus co-infected individuals in Iranian patients. Nigerian Medical Journal, 57(1), 49-53. doi: 10.4103/0300-1652.180560

Saeed, S., Moodie, E. E. M., Strumpf, E., Gill, J., Wong, A., Cooper, C., Walmsley, S., Hull, M., Martel-Laferriere, V., & Klein, M. B. (2018). Real-world impact of direct acting antiviral therapy on health-related quality of life in HIV/Hepatitis C co-infected individuals. Journal of Viral Hepatitis, 25(12), 1507-1514. doi: 10.1111/jvh.12985

Santos, A. D., Araújo, D. C., Menezes, A. F., Lima, S. V. M. A., Góes, M. A. O., & Araújo, K. C. G. M. (2017). Dinâmica espacial e temporal da infecção pelo Vírus da Hepatite C. Arquivos de Ciências Da Saúde, 24(4), 14-19. doi: 10.17696/2318-3691.24.4.2017.802

Scheiner, B., Schwabl, P., Steiner, S., Bucsics, T., Chromy, D., Aichelburg, M. C., Grabmeier-Pfistershammer, K., Trauner, M., Peck-Radosavljevic, M., Reiberger, T., & Mandorfer, M. (2016). Interferon-free regimens improve health-related quality of life and fatigue in HIV/HCV-coinfected patients with advanced liver disease. Medicine, 95(27), e4061. doi: 10.1097/MD.0000000000004061

The WHOQOL Group. (1995). The World Health Organization quality of life assessment (WHOQOL): position paper from the World Health Organization. Social Science & Medicine, 41(10), 1403-1409. doi: 10.1016/0277-9536(95)00112-K

Thein, H., Maruff, P., Krahn, M., Kaldor, J., Koorey, D., Brew, B., & Dore, G. (2007). Cognitive function, mood and health-related quality of life in hepatitis C virus (HCV)-monoinfected and HIV/HCV-coinfected individuals commencing HCV treatment. HIV Medicine, 8(3), 192-202. doi: 10.1111/j.1468-1293.2007.00452.x

Tillmann, H. L., Kaiser, C., Schmidt, R. E., Manns, M., & Stoll, M. (2006). Differential influence of different hepatitis viruses on quality of life in HIV positive patients. European Journal of Medical Research, 11(9), 381–385.

Ursi, E. S. (2005). Prevenção de lesões de pele no perioperatório: revisão integrativa da literatura [Dissertação de mestrado, Escola de Enfermagem de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP , Brasil]. doi: 10.11606/D.22.2005.tde-18072005-095456

Van der Meer, A. J., Veldt, B. J., Feld, J. J., Wedemeyer, H., Dufour, J.-F., Lammert, F., Duarte-Rojo, A., Heathcote, E. J., Manns, M. P., Kuske, L., Zeuzem, S., Hofmann, W. P., de Knegt, R. J., Hansen, B. E., & Janssen, H. L. A. (2012). Association between sustained virological response and all-cause mortality among patients with chronic Hepatitis C and advanced hepatic fibrosis. JAMA, 308(24), 2584-2593. doi: 10.1001/jama.2012.144878

Varescon, I., Untas, A., Sabar, I., Karam, V., Samuel, D., & Duclos-Vallée, J.-C. (2016). Quality of life, anxiety, depression and social support in HCV mono-infected and HIV/HCV coinfected patients waiting for liver transplantation. Transplantation Research Journal, 1(2). doi: 10.16966/2473-1730.106

World Health Organization. (2020a, July 27). Hepatitis C: key facts. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/hepatitis-c.

World Health Organization. (2020b, November 30). HIV/AIDS: key facts. World Health Organization. https://www.who.int/news-room/fact-sheets/detail/hiv-aids.

Yeung, M. W., Young, J., Moodie, E., Rollet-Kurhajec, K. C., Schwartzman, K., Greenaway, C., Cooper, C., Cox, J., Gill, J., Hull, M., Walmsley, S., & Klein, M. B. (2015). Changes in quality of life, healthcare use, and substance use in HIV/hepatitis C coinfected patients after hepatitis C therapy: a prospective cohort study. HIV Clinical Trials, 16(3), 100-110. doi: 10.1179/501100000024

Published

09/08/2021

How to Cite

BONFIM, R. O.; ANDRADE, R. L. de P.; REIS, R. K.; FERREIRA, M. R. L.; ORFÃO, N. H.; VILLA, T. C. S. .; MONROE, A. A. Quality of life of people with HIV/hepatitis C coinfection: a systematic review. Research, Society and Development, [S. l.], v. 10, n. 10, p. e256101018162, 2021. DOI: 10.33448/rsd-v10i10.18162. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/18162. Acesso em: 23 apr. 2024.

Issue

Section

Review Article