Cloroquina relacionada con la malaria y sus prometedoras aplicaciones para el tratamiento con COVID-19

Autores/as

DOI:

https://doi.org/10.33448/rsd-v10i10.18220

Palabras clave:

COVID-19; Cloroquina; Hidroxicloroquina.

Resumen

Objetivo: este artículo describe el uso de la cloroquina como agente antipalúdico con posibles indicaciones antivirus para las infecciones por COVID-19. Métodos: En la construcción de estos artículos se han utilizado búsquedas en línea y literatura gris, cuya base de datos incluye PUBMED Central, BVS / BIREME, Web of Science, Science Direct, Higher Level Personnel Improvement Coordinator (CAPES), The Cochrane Library y PROSPERO. Resultados: la cloroquina y la hidroxicloroquina han mostrado informes clínicos apropiados cuando se asocian con el antibiótico azitromicina. Ha sido autorizado para el tratamiento clínico de formas agudas graves de infecciones por COVID por países como Brasil y EE. UU. Conclusiones: La cloroquina parece tener propiedades antivirales potenciales que pueden ser útiles en el tratamiento de formas agudas graves de COVID-19 asociadas con azitromicina. No obstante, su indicación debe incluir la monitorización ECG debido al riesgo de prolongación del QT cardíaco capaz de provocar muertes súbitas.

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Publicado

16/08/2021

Cómo citar

SAMPAIO, G. M. .; OLIVEIRA, G. H. Q. .; SILVA, H. F.; MORAIS, A. P. A. G. .; SOUZA, J. A.; FREITAS, W. J. L. .; MELO JÚNIOR, P. .; MAIA, S. S. .; SILVA, J. H. S.; AZEVEDO, J. M. C. .; CUNHA, R. S. C. .; MELO, S. P. M. .; SAMBA, L. M. P. .; MUNIZ, C. I. F. .; SANTOS, M. N. .; SILVA, L. B. Cloroquina relacionada con la malaria y sus prometedoras aplicaciones para el tratamiento con COVID-19 . Research, Society and Development, [S. l.], v. 10, n. 10, p. e486101018220, 2021. DOI: 10.33448/rsd-v10i10.18220. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/18220. Acesso em: 3 jul. 2024.

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Ciencias de la salud