Producción ecológica de ácidos grasos nutracéuticos y cosmecéuticos por el hongo oleaginoso Lichtheimia hyalospora UCP 1266 utilizando sustratos renovables
DOI:
https://doi.org/10.33448/rsd-v11i8.30753Palabras clave:
Lípidos microbianos; Hongos Mucorales; Glicerol crudo; Licor de maceración de maíz; Residuos agroindustriales.Resumen
Los ácidos grasos poliinsaturados (AGPIs) son esenciales para las funciones humanas y pueden usarse en nutracéuticos; sin embargo, las fuentes tradicionales son ambientalmente insostenibles. Una estrategia prometedora para reducir los costos de producción de los PUFAs es el uso de fuentes agroindustriales económicas como sustratos en los medios de cultivo para microorganismos oleaginosos. En este estudio, investigamos el potencial del hongo Lichtheimia hyalospora UCP 1266 (aislado del suelo de la Caatinga, Brasil) en la producción de PUFAs, a través de la conversión metabólica de los sustratos alternativos glicerol crudo y licor de maceración de maíz. El cultivo de L. hyalospora UCP 1266 en medio con glucosa (Synthetic Medium for Mucorales - SMM) arrojó 2,1 g/L de biomasa y 0,6 g/L de lípidos totales. Sin embargo, el ensayo 4 del diseño factorial completo de 22, con glicerol crudo 8% y licor de maceración de maíz 8%, proporcionó mayores rendimientos de biomasa (15,5 g/L) y lípidos totales (12,8 g/L). Los lípidos producidos en este medio presentaron una composición de ácidos grasos saturados, monoinsaturados y poliinsaturados (AGS=35,13%, AGMIs=46,09% y AGPIs=18,14%). El microorganismo se mostró prometedor en la producción de omega 6 (ácido linoleico, C18:2), ácido γ-linolénico (C18:3), omega 3 (ácido α-linolénico, C18:3) y omega 9 (ácido oleico, C18:3). :1). Los resultados indicaron a L. hyalospora UCP 1266 como un hongo oleaginoso con gran potencial para su uso en el desarrollo de ingredientes nutracéuticos para alimentos o aplicado en cosmecéuticos y/o nutricosméticos.
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Derechos de autor 2022 Adriana Ferreira de Souza; Manuela Cristina Mota Lins; Marcos Antônio Barbosa de Lima; Rosileide Fontenele da Silva Andrade; Dayana Montero Rodríguez; Norma Buarque Gusmão; Galba Maria de Campos-Takaki
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