Síndrome del Ovario Poliquístico y Vitamina D

Autores/as

DOI:

https://doi.org/10.33448/rsd-v11i11.31907

Palabras clave:

Síndrome del Ovario Poliquístico; Vitamina D; Resistencia a la insulina; Calcitriol.

Resumen

El síndrome del ovario poliquístico (SOP) es uno de los trastornos endocrinos más comunes entre las mujeres en edad reproductiva. Al tratarse de una enfermedad de etiología indefinida y fisiopatología compleja, ha ido cobrando protagonismo la búsqueda de nuevos abordajes para el manejo de los síntomas del SOP mediante métodos no farmacológicos. La deficiencia de vitamina D se asocia con la gravedad de los síntomas de la enfermedad, por lo que existen hipótesis sobre el posible beneficio de la vitamina en el tratamiento del SOP. Además, la vitamina D actúa sobre varios tejidos, incluso en las células beta pancreáticas secretoras de insulina. La presente investigación tuvo como objetivo identificar y explicar las principales mejoras de los parámetros bioquímicos que evalúan la resistencia a la insulina (IR) con suplementos de vitamina D en mujeres con SOP. Se realizó una revisión integrativa de la literatura, con fuentes de los últimos 10 años que utilizan la suplementación vitamínica como estrategia de intervención. En los 10 artículos incluidos se constató que la eficacia de la suplementación con vitamina D sigue siendo hipotética en la respuesta insulínica de mujeres diagnosticadas con la enfermedad, pero es una intervención prometedora. Se logró identificar parámetros metabólicos y fisiológicos que justifican la relación de la vitamina con el metabolismo de la enfermedad, sin embargo, a la fecha aún faltan evidencias concretas de que la suplementación sea efectiva contra los síntomas. Aunque mantener niveles adecuados de vitamina D es esencial para todos los seres humanos, se necesitan más estudios para determinar el papel de la vitamina D en la mejora de los parámetros clínicos del SOP.

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Publicado

01/09/2022

Cómo citar

DIAS, D. de A. M.; SILVA, I. L.; JOVITA, M. C. . Síndrome del Ovario Poliquístico y Vitamina D. Research, Society and Development, [S. l.], v. 11, n. 11, p. e521111131907, 2022. DOI: 10.33448/rsd-v11i11.31907. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/31907. Acesso em: 10 jun. 2025.

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Sección

Ciencias de la salud