Hidrolizados y péptidos bioactivos generados a partir de la hidrólisis de proteína de pollo: Una revisión sistemática de los efectos antihipertensivos en ratas
DOI:
https://doi.org/10.33448/rsd-v11i11.33353Palabras clave:
Hidrolizados de proteína; Péptidos bioactivos; Proteína de pollo; Actividad anti-hipertensiva; Hidrólisis enzimática; Ratas espontáneamente hipertensas.Resumen
En los últimos años se ha estudiado ampliamente la obtención de hidrolizados de proteínas y péptidos a partir de proteínas alimentarias con el fin de conocer mejor no solo sus propiedades nutricionales y funcionales, sino también la posibilidad de su uso como ingredientes en alimentos funcionales. Se sabe que muchas proteínas de la dieta tienen, en su estructura primaria, secuencias peptídicas que, al ser liberadas, pueden ser absorbidas por los enterocitos y modular funciones fisiológicas específicas, además de aportar aminoácidos esenciales y contribuir al metabolismo energético. Por lo tanto, esta revisión tiene como objetivo realizar una revisión sistemática para evaluar la efectividad de estos compuestos bioactivos en el control de la presión arterial en ratas. Además, se evaluó la calidad metodológica de los artículos publicados. Las búsquedas en las bases de datos Scopus, ScienceDirect, ISI Web of Science y PubMed se centraron en estudios sobre el uso de hidrolizados y péptidos obtenidos de la hidrólisis enzimática de diversos tejidos de pollo en ratas. Fue posible verificar que los efectos antihipertensivos positivos dependían principalmente de las condiciones enzimáticas y de la hidrólisis enzimática y el monitoreo de las funciones de los órganos vitales es esencial para la regulación de la presión arterial. Debido a su efectividad y bajo costo, los hidrolizados de proteína de pollo podrían ser una alternativa interesante para aplicaciones biotecnológicas. La administración de hidrolizados y péptidos derivados de proteínas de pollo a ratas espontáneamente hipertensas (SHR, por sus siglas en inglés) muestra una potencial actividad antihipertensiva con probables efectos protectores cardíacos contra el daño a los órganos diana.
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Derechos de autor 2022 Thiago Santos Araujo; Leandro Paes de Brito; José Manoel Wanderley Duarte Neto; Maria Carolina de Albuquerque Wanderley; Wendell Wagner Campos Albuquerque; Polyanna Nunes Herculano; Lorenzo Pastrana ; Maria Taciana Cavalcanti Vieira Soares ; Ana Lúcia Figueiredo Porto
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