Hidrolisados e peptídeos bioativos gerados a partir da hidrólise de proteínas de frango: Uma revisão sistemática dos efeitos anti-hipertensivos em ratos

Autores

DOI:

https://doi.org/10.33448/rsd-v11i11.33353

Palavras-chave:

Hidrolisados proteicos; Peptídeos bioativos; Proteína de frango; Atividade anti-hipertensiva; Hidrólise enzimática; Ratos espontaneamente hipertensos.

Resumo

Nos últimos anos, a obtenção de hidrolisados proteicos e peptídeos a partir de proteínas alimentares tem sido amplamente estudada com o intuito de melhor compreender não apenas suas propriedades nutricionais e funcionais, mas também a possibilidade de sua utilização como ingredientes em alimentos funcionais. Sabe-se que muitas proteínas da dieta possuem, em sua estrutura primária, sequências peptídicas que, ao serem liberadas, podem ser absorvidas pelos enterócitos e modular funções fisiológicas específicas, além de fornecer aminoácidos essenciais e contribuir para o metabolismo energético. Portanto, esta revisão tem o objetivo de realizar uma revisão sistemática para avaliar a eficácia desses compostos bioativos no controle da pressão arterial em ratos. Além disso, avaliou-se a qualidade metodológica dos artigos publicados. As buscas nas bases de dados Scopus, ScienceDirect, ISI Web of Science e PubMed foram focadas em estudos sobre o uso de hidrolisados e peptídeos obtidos a partir da hidrólise enzimática de diversos tecidos de frango em ratos. Foi possível verificar que os efeitos anti-hipertensivos positivos foram dependentes principalmente das condições enzimáticas e de hidrólise enzimática e o monitoramento das funções dos órgãos vitais é essencial para a regulação da pressão arterial. Devido à sua eficácia e baixo custo, os hidrolisados de proteína de frango podem ser uma alternativa interessante para aplicações biotecnológicas. A administração de hidrolisados ​​e peptídeos derivados de proteínas de frango a ratos espontaneamente hipertensos (SHR) exibe um potencial atividade anti-hipertensiva com prováveis ​​efeitos protetores cardíacos contra danos em órgãos-alvo.

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19/08/2022

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ARAUJO, T. S. .; BRITO, L. P. de .; DUARTE NETO, J. M. W.; WANDERLEY, M. C. de A. .; ALBUQUERQUE, W. W. C. .; HERCULANO, P. N. .; PASTRANA , L. .; SOARES , M. T. C. V. .; PORTO, A. L. F. Hidrolisados e peptídeos bioativos gerados a partir da hidrólise de proteínas de frango: Uma revisão sistemática dos efeitos anti-hipertensivos em ratos. Research, Society and Development, [S. l.], v. 11, n. 11, p. e181111133353, 2022. DOI: 10.33448/rsd-v11i11.33353. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/33353. Acesso em: 17 jul. 2024.

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v. 11 n. 11

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Ciências Agrárias e Biológicas

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Copyright (c) 2022 Thiago Santos Araujo; Leandro Paes de Brito; José Manoel Wanderley Duarte Neto; Maria Carolina de Albuquerque Wanderley; Wendell Wagner Campos Albuquerque; Polyanna Nunes Herculano; Lorenzo Pastrana ; Maria Taciana Cavalcanti Vieira Soares ; Ana Lúcia Figueiredo Porto

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