Actividad biológica de microalgas frente a dermatofitos: Revisión

Autores/as

DOI:

https://doi.org/10.33448/rsd-v11i11.33404

Palabras clave:

Microalgas; Bioextractos; Dermatofitosis; Actividad antifúngica.

Resumen

Las microalgas se presentan como uma fuente valiosa de metabolitos biológicamente activos, con potencial uso farmacológico. En la industria farmacéutica, los extractos de microalgas se han destacado por sus importantes actividades biológicas, incluso la actividad antifúngica. Las dermatofitosis son micosis cutáneas causadas por hongos denominados dermatofitos, microorganismo que presenta biotropismo para los tejidos queratinizados. El objetivo de este trabajo consiste em generar una revisión bibliográfica respecto la actividad biológica de extractos y compuestos de microalgas frente a hongos dermatofitos. Consiste en una revisión narrativa de la literatura, en que se ha utilizado los portales web y bases de datos de PubMed, LILACS, SciELO y Google Scholar. Tras la búsqueda, se han seleccionado 18 artículos publicados entre los años 1960 y 2021, en inglés y francés. Se han evaluado cuatro grupos de microalgas respecto a su actividad antifúngica: clorofitas, diatomeas, dinoflagelados y cianobacterias, totalizando 40 especies de microalgas probadas contra 19 especies de dermatofitos. Las diatomeas y las cianobacterias tienen el mayor número de pruebas realizadas contra los dermatofitos. Las especies de dermatofitos más estudiadas han sido T. rubrum y T. menthagrophytes. Los extractos obtenidos de S. platensis, C. braunii, T. nodosa y T. tenuis han mostrado una mayor actividad inhibitoria em los hongos estudiados, además de compuestos aislados de las especies de dinoflagelados Goniodoma sp., G. toxicus y Amphidinium sp.. La falta de estandarización de las pruebas y el hecho de que ya se hayan identificado las actividades antifúngicas de las especies de microalgas para el control de los dermatofitos, anima a realizar más estudios centrados en la biodiversidad y el efecto sinérgico con los fármacos comerciales.

Citas

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Publicado

17/08/2022

Cómo citar

LAGE, V. M. G. B.; DEEGAN, K. R.; SANTOS, G. F.; BARBOSA, C. de J.; LIMA, S. T. da C. Actividad biológica de microalgas frente a dermatofitos: Revisión. Research, Society and Development, [S. l.], v. 11, n. 11, p. e126111133404, 2022. DOI: 10.33448/rsd-v11i11.33404. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/33404. Acesso em: 1 jul. 2024.

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