Manifestações bucais da COVID-19: revisão integrativa da literatura

Ingrid Cristina Nascimento  Santos; Helvécio  Marangon Júnior; Thiago de Amorim  Carvalho

doi:10.33448/rsd-v11i13.35285

Autores/as

Ingrid Cristina Nascimento Santos Centro Universitário de Patos de Minas https://orcid.org/0000-0003-2561-487X
Helvécio Marangon Júnior Centro Universitário de Patos de Minas https://orcid.org/0000-0002-9709-6795
Thiago de Amorim Carvalho Centro Universitário de Patos de Minas https://orcid.org/0000-0003-1153-0931

DOI:

https://doi.org/10.33448/rsd-v11i13.35285

Palabras clave:

Covid-19; Virus; Lesión.

Resumen

Introducción: Se han reportado lesiones orales en pacientes con COVID-19 con cambios en la mucosa oral, incluyendo efectos de infecciones concomitantes. Entre las infecciones concomitantes consideradas dignas de mención se encuentran: Herpes, Candidiasis y Mucormicosis. Objetivo: El objetivo de este estudio fue caracterizar las manifestaciones bucales en adultos portadores de COVID-19. Métodos: Se realizó una revisión integrativa de la literatura, buscando en las bases de datos PUBMED, SCIELO, PERIODICOS CAPES y LILACS/BVS/BIREME con las siguientes palabras clave de búsqueda: “manifestacion oral”, “lesiones mucosas”, “covid-19”, “adultos” y “periodontales” asociados mediante el operador booleano “y”. Resultados: Después de aplicar los criterios de elegibilidad enumerados por la estrategia PRISMA-ScR, se seleccionaron 21 artículos para responder a la pregunta: “¿Cuáles son las manifestaciones orales y periodontales más comunes en adultos que han tenido COVID-19?”. Conclusión: Se advierte que el COVID-19 y sus manifestaciones orales han sido reportadas y relacionadas, pero se necesitan más estudios para esclarecer y hacer más clara esta relación.

Citas

Aragoneses, J., Suárez, A., Algar, J., Rodríguez, C., López-Valverde, N., & Aragoneses, J. M. (2021). Oral Manifestations of COVID-19: Updated Systematic Review With Meta-Analysis. Frontiers in Medicine, 8. https://doi.org/10.3389/fmed.2021.726753

Bhujel, N., Zaheer, K., & Singh, R. P. (2021). Oral mucosal lesions in patients with COVID-19: a systematic review. The British Journal of Oral & Maxillofacial Surgery, 59(9), 1024–1030. https://doi.org/10.1016/j.bjoms.2021.06.011

Brandão, T. B., Gueiros, L. A., Melo, T. S., Prado-Ribeiro, A. C., Nesrallah, A. C. F. A., Prado, G. V. B., Santos-Silva, A. R., & Migliorati, C. A. (2020). Oral lesions in patients with SARS-CoV-2 infection: could the oral cavity be a target organ? Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. https://doi.org/10.1016/j.oooo.2020.07.014

Brandini, D. A., Takamiya, A. S., Thakkar, P., Schaller, S., Rahat, R., & Naqvi, A. R. (2021). Covid-19 and oral diseases: Crosstalk, synergy or association? Reviews in Medical Virology, 31(6), e2226. https://doi.org/10.1002/rmv.2226

Carvalho, T. de A., Silva, D. L. M., Oliveira, L. C., Machado, F. C., Andrade, R. S. de, & Novais, V. R. (2021). O que a cavidade oral pode mostrar em pacientes com COVID-19? Revisão integrativa da literatura. Research, Society and Development, 10(4), e17710414072. https://doi.org/10.33448/rsd-v10i4.14072

Cavezzi, A., Troiani, E., & Corrao, S. (2020). COVID-19: hemoglobin, iron, and hypoxia beyond inflammation. A narrative review. Clinics and Practice, 10(2). https://doi.org/10.4081/cp.2020.1271

CDC Weekly, C. (2020). The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) — China, 2020. China CDC Weekly, 2(8), 113–122. https://doi.org/10.46234/ccdcw2020.032

Cruz Tapia, R. O., Peraza Labrador, A. J., Guimaraes, D. M., & Matos Valdez, L. H. (2020). Oral mucosal lesions in patients with SARS‐CoV‐2 infection. Report of four cases. Are they a true sign of COVID‐19 disease? Special Care in Dentistry, 40(6), 555–560. https://doi.org/10.1111/scd.12520

Cuevas-Gonzalez, M. V., Espinosa-Cristóbal, L. F., Donohue-Cornejo, A., Tovar-Carrillo, K. L., Saucedo-Acuña, R. A., García-Calderón, A. G., Guzmán-Gastelum, D. A., & Cuevas-Gonzalez, J. C. (2021). COVID-19 and its manifestations in the oral cavity: A systematic review. Medicine, 100(51), e28327. https://doi.org/10.1097/MD.0000000000028327

Dalipi, Z. S., Dragidella, F., & Dragidella, D. K. (2021). Oral Manifestations of Exudative Erythema Multiforme in a Patient with COVID-19. Case Reports in Dentistry, 2021, 1–8. https://doi.org/10.1155/2021/1148945

Doceda, M.V., Gavriiloglou, M., Petit, C., Huck, O. (2022). Oral Health Implications of SARS-CoV-2/COVID-19: A Systematic Review. Oral Health Prev Dent. 27;20(1):207-218. https://doi.org/10.3290/j.ohpd.b2960801

Dziedzic, A., & Wojtyczka, R. (2020). The impact of coronavirus infectious disease 19 (COVID‐19) on oral health. Oral Diseases. https://doi.org/10.1111/odi.13359

Eita, A. A. B. (2021). Parosmia, Dysgeusia, and Tongue Features Changes in a Patient with Post-Acute COVID-19 Syndrome. Case Reports in Dentistry, 2021, 1–5. https://doi.org/10.1155/2021/3788727

Erbaş, G. S., Botsali, A., Erden, N., Arı, C., Taşkın, B., Alper, S., & Vural, S. (2022). COVID-19-related oral mucosa lesions among confirmed SARS-CoV-2 patients: a systematic review. International Journal of Dermatology, 61(1), 20–32. https://doi.org/10.1111/ijd.15889

Espinoza-Espinoza,D.A.K., Dulanto-Vargas, J.A., Cáceres-LaTorre, O.A., Lamas-Castillo, F.E., Flores-Mir, C., Cervantes-Ganoza, L.A., López-Gurreonero, C., Ladera-Castañeda, M.I., Cayo-Rojas, C.F.(2021). Association Between Periodontal Disease and the Risk of COVID-19 Complications and Mortality: A Systematic Review. J Int Soc Prev Community Dent., 30;11(6):626-638. https://doi.org/10.4103/jispcd.JISPCD_189_21

Galván Casas, C., Català, A., Carretero Hernández, G., Rodríguez‐Jiménez, P., Fernández Nieto, D., Rodríguez‐Villa Lario, A., Navarro Fernández, I., Ruiz‐Villaverde, R., Falkenhain, D., Llamas Velasco, M., García‐Gavín, J., Baniandrés, O., González‐Cruz, C., Morillas‐Lahuerta, V., Cubiró, X., Figueras Nart, I., Selda‐Enriquez, G., Romaní, J., Fustà‐Novell, X., & Melian‐Olivera, A. (2020). Classification of the cutaneous manifestations of COVID‐19: a rapid prospective nationwide consensus study in Spain with 375 cases. British Journal of Dermatology. https://doi.org/10.1111/bjd.19163

Gupta, S., Jawanda, M. K., Taneja, N., & Taneja, T. (2021). A systematic review of Bell’s Palsy as the only major neurological manifestation in COVID-19 patients. Journal of Clinical Neuroscience, 90, 284–292. https://doi.org/10.1016/j.jocn.2021.06.016

Kitakawa, D., Oliveira, F.E., Neves de Castro, P., Carvalho, L.F.C.S. (2020).Short report - Herpes simplex lesion in the lip semimucosa in a COVID-19 patient. Eur Rev Med Pharmacol Sci., 24(17):9151-9153. doi: 10.26355/eurrev_202009_22863.

Latorraca, C.D.O.C., Rodrigues, M., Pacheco, R.L., Martimbianco, A.L.C., Riera, R. (2019). Busca em bases de dados eletrônicas da área da saúde: por onde começar. Diagn Tratamento, 24(2):59-63.

Mariz, B. A. L. A., Brandão, T. B., Ribeiro, A. C. P., Lopes, M. A., & Santos-Silva, A. R. (2020). New Insights for the Pathogenesis of COVID-19-Related Dysgeusia. Journal of Dental Research, 99(10), 1206–1206. https://doi.org/10.1177/0022034520936638

Nejabi, M. B., Noor, N. A. S., Raufi, N., Essar, M. Y., Ehsan, E., Shah, J., Shah, A., & Nemat, A. (2021). Tongue ulcer in a patient with COVID-19: a case presentation. BMC Oral Health, 21. https://doi.org/10.1186/s12903-021-01635-8

Nijakowski, K., Wyzga, S., Singh, N., Podgórski, F., & Surdacka, A. (2022). Oral Manifestations in SARS-CoV-2 Positive Patients: A Systematic Review. Journal of Clinical Medicine, 11(8), 2202. https://doi.org/10.3390/jcm11082202

Orilisi, G., Mascitti, M., Togni, L., Monterubbianesi, R., Tosco, V., Vitiello, F., Santarelli, A., Putignano, A., & Orsini, G. (2021). Oral Manifestations of COVID-19 in Hospitalized Patients: A Systematic Review. International Journal of Environmental Research and Public Health, 18(23), 12511. https://doi.org/10.3390/ijerph182312511

Saleh, W., Ata, F., & Elashry, M. M. (2021a). Is COVID-19 infection triggering oral herpes zoster? A case report. SAGE Open Medical Case Reports, 9, 2050313X2110657. https://doi.org/10.1177/2050313x211065793

Saleh, W., SHawky, E., Halim, G. A., & Ata, F. (2021b). Oral lichen planus after COVID-19, a case report. Annals of Medicine and Surgery, 72, 103051. https://doi.org/10.1016/j.amsu.2021.103051

Santos, J.A.D., Normando, A. G. C., Carvalho da Silva, R. L., Acevedo, A. C., De Luca Canto, G., Sugaya, N., Santos-Silva, A. R., & Guerra, E. N. S. (2020a). Oral Manifestations in Patients with COVID-19: A Living Systematic Review. Journal of Dental Research, 100(2), 141–154. https://doi.org/10.1177/0022034520957289

Santos, J.A.D., Normando, A. G. C., Carvalho da Silva, R. L., Acevedo, A. C., De Luca Canto, G., Sugaya, N., Santos-Silva, A. R., & Guerra, E. N. S. (2021). Oral Manifestations in Patients with COVID-19: A 6-Month Update. Journal of Dental Research, 100(12), 1321–1329. https://doi.org/10.1177/00220345211029637

Santos, J.A.D., Normando, A. G. C., Carvalho da Silva, R. L., De Paula, R. M., Cembranel, A. C., Santos-Silva, A. R., & Guerra, E. N. S. (2020b). Oral mucosal lesions in a COVID-19 patient: New signs or secondary manifestations? International Journal of Infectious Diseases, 97, 326–328. https://doi.org/10.1016/j.ijid.2020.06.012

Sarode, G. S., Sarode, S. C., Gadbail, A. R., Gondivkar, S., Sharma, N. K., & Patil, S. (2020). Are oral manifestations related to SARS-CoV-2 mediated hemolysis and anemia? Medical Hypotheses, 110413. https://doi.org/10.1016/j.mehy.2020.110413

Sharma, P., Malik, S., Wadhwan, V., Palakshappa, S.G., & Singh, R. (2022). Prevalence of oral manifestations in COVID‐19: A systematic review. Reviews in Medical Virology, https://doi.org/10.1002/rmv.2345

Uzêda-E-Silva,V.D., Sá, I.B., Martins, J., Pedreira, N., Vieira, V.P.S., Silva, B.H.M.(2021) Oral lesions associated with COVID-19: A systematic review. Stomatologija, 23(1):3-8.

Vaira, L. A., Deiana, G., Fois, A. G., Pirina, P., Madeddu, G., De Vito, A., Babudieri, S., Petrocelli, M., Serra, A., Bussu, F., Ligas, E., Salzano, G., & De Riu, G. (2020). Objective evaluation of anosmia and ageusia in COVID ‐19 patients: Single‐center experience on 72 cases. Head & Neck. https://doi.org/10.1002/hed.26204

Wang, C., Wu, H., Ding, X., Ji, H., Jiao, P., Song, H., Li, S., & Du, H. (2020). Does infection of 2019 novel coronavirus cause acute and/or chronic sialadenitis? Medical Hypotheses, 140, 109789. https://doi.org/10.1016/j.mehy.2020.109789

WHO. (2022). Painel da OMS COVID-19. Organização Mundial da Saúde. Retrieved Sep, 2022, from https://covid19.who.int/

Xu, H., Zhong, L., Deng, J., Peng, J., Dan, H., Zeng, X., Li, T., & Chen, Q. (2020a). High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa. International Journal of Oral Science, 12. https://doi.org/10.1038/s41368-020-0074-x

Xu, J., Li, Y., Gan, F., Du, Y., & Yao, Y. (2020b). Salivary Glands: Potential Reservoirs for COVID-19 Asymptomatic Infection. Journal of Dental Research, 99(8), 989. https://doi.org/10.1177/0022034520918518

Zhou, P., Yang, X.L., Wang, X.G., Hu, B., Zhang, L., Zhang, W., Si, H.R., Zhu, Y., Li, B., Huang, C.L., Chen, H.D., Chen, J., Luo, Y., Guo, H., Jiang, R.D., Liu, M.Q., Chen, Y., Shen, X.R., Wang, X., & Zheng, X.S. (2020). A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature, 579(7798). https://doi.org/10.1038/s41586-020-2012-7

Manifestaciones orales del COVID-19: revisión integrativa de literatura

Autores/as

DOI:

Palabras clave:

Resumen

Citas

Descargas

Publicado

Cómo citar

Número

Sección

Licencia

JOURNAL METRICS

Idioma

Enviar un artículo