Comparative study of video-assisted thoracic surgery (VATS) and open thoracotomy: an analysis using propensity score matching

Authors

DOI:

https://doi.org/10.33448/rsd-v11i15.37521

Keywords:

Open thoracotomy; VATS; Propensity score matching; Lobectomy; Pneumonectomy.

Abstract

Introduction: To compare results of video-assisted thoracic surgical approach (VATS) and of open thoracotomy in performing lobectomy and pneumonectomy regarding hospital stay, chest drainage time, morbidity and mortality. Methods: An observational retrospective study of 149 patients undergoing lobectomy and pneumonectomy for open thoracotomy or VATS from January 2018 to December 2022. Patient characteristics were compared using Student’s t-test, χ2 Pearson and Fisher's exact test. We performed the Propensity score matching model of analysis for data fitting. Complications were assessed by multivariate logistic regression model for age, sex, lung function, histology, comorbidities and smoking factors. We used Kaplan-Meier estimator and Cox regression to assess hospital stay and thoracic drainage. Results: We performed 130 open thoracotomy and lobectomy by VATS 19. The propensity score model excluded 111 patients in the thoracotomy group. The patients in the VATS group had lower thoracic drainage time (p= 0.011; HR= 0.40; IC95% 0.19 to 0.84) and hospital stay (p= 0.001; HR= 0.23; IC95% 0,10 to 0,54) in the Cox regression model. Multivariate logistic regression for complications as a dependent variable showed VATS with a reduction factor (p = 0.02; OR = 0.13; CI 0.023 to 0.730). There were no significant differences in the characteristics, postoperative complications and mortality between the groups (p = 0.31). Conclusion: VATS is associated with decreased hospital stay, less chest drainage time and less post-operative complications.

Author Biography

Heyder Magalhaes Estevão , Universidade Federal do Rio Grande do Norte; Universidade Federal de Campina Grande

Médico do Hospital Universitário Alcides Carneiro UFCG

References

Bertrand, P. C., Regnard, J. F., Spaggiari, L., Levi J F, Magdeleinat P, & Guibert L, (1996). Immediate and long-term results after surgicaltreatment of primary spontaneous pneumothorax by VATS. Ann Thorac Surg 1996; 61(6), 1641-1645.

Blades, B., & Kent, E. M. Individual ligation technique for lower lobectomy. J Thorac Surg. 1940; 10:84-101.

Cao C., Manganas C., Ang S. C., & Yan T D (2022). A meta-analysis of unmatched and matched patients comparing video-assisted thoracoscopic lobectomy and conventional open lobectomy. Ann Cardiothorac Surg; 1(1), 16-23.

Carvalho, W. R., Forte V., Saad Junior, R., & Netto, M. X. (2018). Cirurgia Torácica Geral. São Paulo: Atheneu/Editora.

Churchill, E. D. Lobectomy and pneumonectomy in bronchiectasis of cystic disease(1937). J Thorac Surg. 1937; 6:286.

Churchill, E D. The surgical treatment of carcinoma of the lung(1933). J Thorac Surg.; 2, 254-261.

Coelho, F. L P. & Franco, R P (2019). Avanços da Lobectomia Por Cirurgia Torácica Videoassistida no tratamento do Câncer de Pulmão. 9(‘8), (2019): a contemporaneidade e novas perspectivas na cirurgia médica jul./dez. (2019) /

Davie,s H. M. Recent advances in the surgery of the lung and pleura (1913). Britsh J Surg; 1, 228-258.

Flores, R. M., Ihekweazu U., & Dycoco J., (2020) Video-assisted thoracoscopic surgery (VATS) lobectomy: Catastrophic intraoperative complications. J Thorac Cardiovasc Surg.;142(6),1412-1417.

Flores, R. M., Park, B. J., Dycoco, J., Aronova, A., Hirth, Y. & Rizk, N. P, (2019). Lobectomy by video-assisted thorcic surgery (VATS) versus thoracotomy for lung cancer. J Thorac Cardiovasc Surg; 138(1), 11-18.

Granham, E. A., & Singer, J .J. Successful removal of an entire lung for carcinoma of the bronchus (1972). JAMA. 1933; 101(18), 1371-.

Ilonen, I. K., Räsänen, J. V., Knuuttila, A., Salo, J. A. & Sihvo, E. I. Anatomic thoracoscopic lung resection for non-small cell lung cancer in stage I is associated with less morbidity and shorter hospitalization than thoracotomy. Acta Oncol. 2011; 50(7): 1126-1132.

Jacobaeus, H.C., (2022). Über die Moglishkeit die zystoskopie bei Untersuchung seroser, Hohlugen anzuwenden. Much Med Wochensch.; 57, 2090-2092.

Kirby, T. J., Mack, M J, Landreneau, R. J., & Rice, T. W.(1995). Lobectomy--video-assisted thoracic surgery versus muscle-sparing thoracotomy. A randomized trial. J Thorac Cardiovasc Surg.;109(5), 997-1001; discussion 1001-1002.

Licht, P. B., Jørgensen, O .D., Ladegaard, L., & Jakobsen, E., (2013;). A national study of nodal upstaging after thoracoscopic versus open lobectomy for clinical stage i lung cancer. Ann Thorac Surg 96(3), 943-950.

McKenna, R. J. (2018). Complications and Learning Curves for Video-Assisted Thoracic Surgery Lobectomy. Thorac Surg Clin; 18(3), 275-280.

Nagahiro, I., Andou, A., Aoe, M., Sano, Y., Date, H., & Shimizu, N. (2021). Pulmonary function, postoperative pain, and serum cytokine level after lobectomy: A comparison of VATS and conventional procedure. Ann Thorac Surg; 72(2), 362-365.

Nagai, S., Imanishi, N., Matsuoka, T., Matsuoka, K., Ueda, M., & Miyamoto, Y. (2014). Video-assisted thoracoscopic pneumonectomy:Retrospective outcome analysis of 47 consecutive patients. Ann Thorac Surg 97(6), 1908-1913.

Rosenbaum, P. R., & Rubin, D. B. The Central Role of the Propensity Score in Observational Studies for Causal Effects. Biometrika; 70(1), 41-55.

Rubin, D. B. (1983). Using Propensity Scores to Help Design Observational Studies: Aplication to the Tobacco Litigation. Heal Serv and Outcomes Res Methodol. 2001; 2(3),169-188.

Samson, P., Guitron, J., Reed, M. F., Hanseman, D .J., & Starnes, S. L.(2013). Predictors of conversion to thoracotomy for video-assisted thoracoscopic lobectomy: A retrospective analysis and the influence of computed tomography-based calcification assessment. J Thorac Cardiovasc Surg145(6),1512-1518.

Scott, W. J., Matteotti, R. S., Egleston, B. L., Oseni, S., & Flaherty, J. F. (2010). A comparison of perioperative outcomes of video-assisted thoracic surgical (VATS) lobectomy with open thoracotomy and lobectomy: results of an analysis using propensity score based weighting. Ann Surg Innov Res.; 4(1),1.

Sotto-Mayor, (2006). Marcos históricos no estudo do cancro do pulmão. Rev Port Pneumol; 12(4): 401-446.

Walker, W. S., & Leaver, H. A. (2007). Immunologic and Stress Responses Following Video-Assisted Thoracic Surgery and Open Pulmonary Lobectomy in Early Stage Lung Cancer. Thorac Surg Clin; 17(2): 241-249.

Wang, J., & Donnan, P. T. (2001). Propensity score methods in drug safety studies: practice, strengths and limitations. Pharmacoepidemiol Drug Saf; 10(4), 341-344.

Published

22/11/2022

How to Cite

ESTEVÃO , H. M. .; LEITE, I. F. .; SIQUEIRA, A. L. . L. G. de .; SANTOS, T. R. .; RAMALHO , J. P. G. .; SANTOS , J. S. .; CRUZ , E. M. M. S. .; JESUS, D. R. R. de .; MELO, V. de A. .; MENDES, P. A. da C. . Comparative study of video-assisted thoracic surgery (VATS) and open thoracotomy: an analysis using propensity score matching. Research, Society and Development, [S. l.], v. 11, n. 15, p. e422111537521, 2022. DOI: 10.33448/rsd-v11i15.37521. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/37521. Acesso em: 24 apr. 2024.

Issue

Section

Health Sciences