El papel de la suplementación oral con inmunonutrientes en la respuesta inflamatoria en pacientes con COVID-19
DOI:
https://doi.org/10.33448/rsd-v9i9.7115Palabras clave:
Nutriente; Sistema inmunológico; Citoquinas; Infección; Coronavirus.Resumen
Introduccion: El coronavirus relacionado con Sars-CoV-2 se ha extendido a casi todos los países, causando COVID-19. La gravedad de COVID-19 se basa en la inflamación causada por la tormenta de citoquinas. Los marcadores inflamatorios sugieren una explicación molecular para la aparición de enfermedades graves y representan un posible tratamiento. Objetivo: Esta revisión tiene como objetivo analizar la verosimilitud del uso de suplementos orales con inmunonutrientes. Discussion: La inmunonutrición estudia las interacciones entre nutrición, sistema inmunológico, infección e inflamación tisular. La arginina es un aminoácido fundamental en los procesos de estrés metabólico. Su deficiencia implica capacidad de respuesta inmune. Se ha demostrado que los ácidos grasos de la serie 3 mejoran el cumplimiento pulmonar, la oxigenación, el tiempo de ventilación mecánica y la unidad de cuidados intensivos en pacientes con síndrome de dificultad respiratoria aguda. Esencial para la inmunidad mediada por células y la función de linfocitos T, se ha demostrado que los nucleótidos dietéticos mejoran la citotoxicidad de las células asesinas naturales. Teniendo en cuenta que la relación inversamente proporcional entre la presencia de LA-6 y la función de células TnF y T-cell está bien establecida en pacientes con COVID-19, esto refuerza la idea de que el control de la liberación de estos biomarcadores puede ser una manera de tratar esta enfermedad. Conclusion: En este escenario, esta revisión plantea la posibilidad de utilizar la inmunonutrición para mejorar la respuesta inmune de las personas afectadas por COVID-19.
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Derechos de autor 2020 Rodrigo Fernandes Weyll Pimentel; Magno Conceição das Merces ; Dandara Almeida Reis da Silva; Márcio Costa de Souza ; Monique Magnavita Borba da Fonseca Cerqueira ; Pedro Carlos Muniz de Figueiredo; Amália Ivine Costa Santana; Douglas de Souza e Silva ; Sandra Lúcia Fernandes; Isolda Padro de Negreiros Nogueira Maduro; Eliene de Almeida Soriano; Anderson Reis de Sousa
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