Rendimiento de bacteriófagos en bacterias causantes de mastitis

Autores/as

DOI:

https://doi.org/10.33448/rsd-v9i10.8541

Palabras clave:

Acción antibacteriana; Acción anti-biofilm; Productos naturales; Fagos; Endolisina.

Resumen

                            La mastitis es una enfermedad del tejido mamario que tiene una alta incidencia en el hato lechero con implicaciones que van desde la salud hasta la economía del sector. El uso de la terapia con antibióticos es de amplia aplicación, sin embargo, es necesaria la búsqueda de nuevas perspectivas en el manejo y tratamiento de esta enfermedad. La investigación en fagos es anterior al descubrimiento de los antibióticos, pero con la aparición de estas sustancias y su eficacia en el tratamiento de infecciones, esta terapia quedó en el olvido por un tiempo y resurgió como una alternativa para combatir las bacterias multirresistentes. La relación entre los fagos, las bacterias y el sistema inmunológico es única y genera una amplia gama de oportunidades, algunas de las cuales aún están poco estudiadas. Así, el objetivo de esta revisión fue analizar el uso de bacteriófagos en el control de la mastitis bovina y su asociación con otros productos naturales en la actualidad. Las investigaciones han mostrado una actividad antibacteriana y antibiopelícula efectiva, y las interacciones de los fagos con otras sustancias de origen natural aparecen como una vía viable aún poco explorada para la enfermedad, pero que ya se vislumbra en relación a los principales agentes causantes de mastitis. También se abordan cuestiones sobre la seguridad y los caminos para el futuro de la terapia con fagos con el fin de señalar los puntos en los que la investigación aún debe avanzar y las principales ventajas y dificultades en esta área.

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22/09/2020

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BARBOSA, L. N. .; ALMADA, A. F. B. de .; SCHMITZ JUNIOR, J. A.; VECHIO, M. A. D. .; BEZERRA , K. .; ESPOLADOR, G. F. .; SANTOS, M. C. dos .; MORETTO, L. de F. .; SANTOS, I. C. dos .; MARTINS, L. de A. .; GONÇALVES , D. D. . Rendimiento de bacteriófagos en bacterias causantes de mastitis. Research, Society and Development, [S. l.], v. 9, n. 10, p. e1849108541, 2020. DOI: 10.33448/rsd-v9i10.8541. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/8541. Acesso em: 25 nov. 2024.

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