Influência da infecção viral no processo de reparo das lesões periapicais: uma revisão narrativa
DOI:
https://doi.org/10.33448/rsd-v10i3.13134Palavras-chave:
Citomegalovírus; Herpes Simples; HIV; Periodontite apical; Saúde oral; Vírus Epstein-Barr.Resumo
Fundamento: O tratamento endodôntico tem como principal objetivo eliminar os microrganismos e seus produtos tóxicos, permitindo o reestabelecimento das defesas do organismo e consequentemente, o reparo dos tecidos periapicais. No entanto, inúmeros fatores podem afetar o reparo periapical, como os materiais obturadores empregados, a presença de microrganismos, fatores sistêmicos e mais recente, as infecções virais têm sido associadas ao agravamento das lesões periapicais. Objetivo: Discutir a relação das principais infecções virais com as manifestações da periodontite apical e como estas infecções podem influenciar no reparo dos tecidos periapicais. Conclusão: A literatura não estabelece uma relação causa-efeito entre a presença de vírus nos tecidos periapicais e o aumento da patogenicidade da periodontite apical. No entanto, mais estudos devem ser realizados para afirmar o potencial viral nos tecidos periapicais, uma vez que a literatura mostra uma resposta imunológica na periodontite apical desencadeada por vírus na fase lítica, semelhante a observada a outros patógenos, sendo capaz de exacerbar a resposta inflamatória, aumentar a reabsorção óssea e ainda interferir no reparo dos tecidos periapicais.
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