Use of the infusion of Sonchus oleraceus leaves for the treatment of vitiligo

Authors

DOI:

https://doi.org/10.33448/rsd-v10i4.13824

Keywords:

Vitiligo; Sonchus; Milkweed; Medicinal plants.

Abstract

Objective: To describe the results of using the infusion of Sonchus oleraceus leaves for the treatment of vitiligo. Method: Qualitative study, carried out in a border municipality in the State of Paraná, in the second half of 2019 and early 2020, with individuals who used the infusion of Sonchus oleraceus. A semi-structured instrument was used with questions regarding the use of that plant. Interviews were conducted, with thematic analysis of the results. Results: Participants were 11 individuals with vitiligo, seven women and four men, aged between 25 and 61 years (mean of 42 years), with depigmentation in various regions of the body. They used the infusion of the leaves of Sonchus oleraceus in the period from 3 to 13 months (average of 9 months), and prepared the tea with 5 leaves in a liter of water, consuming an average of 700 mL a day. Most individuals observed pigmentation in depigmented areas. The pigmentation of the areas was observed between 3 and 6 months after the start of the infusion (mean of 4 months). Related to the disease, the participants expressed sadness, boredom and difference, with a direct impact on daily life, but with the improvement after the use of the plant, happiness and satisfaction opened up space for a new life. Conclusion: The infusion of Sonchus oleraceus caused the pigmentation of white spots in patients with vitiligo, and the results of herbal therapy gave positive feelings to the participants.

References

Alothman, E. A., Awaad, A. S, Safhi, A. A., Almoqren, S. S., El-Meligy, R. M., Zain, Y. M, Alasmary, A. S. & Alqasoumi, S. I. (2018). Evaluation of anti-ulcer and ulcerative colitis of Sonchus oleraceus L. Saudi Pharmaceutical Journal, 26(1), 956-959.

Dalla, A., Parsad, D., Vinay, K., Thakur, V. & Kumaran, M. S. (2020). A prospective study to assess the efficacy of various surgical modalities in treatment of stable vitiligo patches over resistant sites. International journal of dermatology, 59(7), 837-842.

Doulah, A., Mahmoodi, G. & Borujeni, M. P. (2020). Evaluation of the pre-treatment effect of centella asiatica medicinal plants on long-term potentiation (LTP) in rat model of Alzheimer's disease, Neuroscience letters, 11(729), 135026.

Fujimaki, T., Mori, S., Horikawa, M. & Fukui, Y. (2018). Isolation of proanthocyanidins from red wine, and their inhibitory effects on melanin synthesis in vitro. Food chemistry, 15(248), 61-69.

Grimes, P. E. & Miller, M. M. (2018). Vitiligo: patient stories, self-esteem, and the psychological burdenof disease. International Journal of Women's Dermatology, 4(1), 32-37.

Kapoor, R., Dhatwalia, S. K., Kumar, R., Rani, S. & Parsad, D. (2020). Emerging role of dermal compartment in skin pigmentation: comprehensive review. Journal of the European Academy of Dermatology and Venereology, 34(12), 2757-2765.

Kota, R. S., Vora, R.V., Varma, J. R., Kota, S. K., Patel, T. M. & Ganjiwale, J. (2019). Study on assessment of quality of life and depression in patients of vitiligo. Indian Dermatology Online Journal, 10(2), 153-157.

Lai, Y. C., Yew, Y. W., Kennedy, C. & Schwartz, R. A, (2017). Vitiligo and depression: a systematic review and meta‐analysis of observational studies. The British journal of dermatology, 177(3), 708-718.

Mamoon, U., Alamzeb, R. M., Ali, S., Ullah, S., Shah, A. Z, Naz, I. & Khan, M. R. (2019). The chemistry and pharmacology of alkaloids and allied nitrogen compounds from artemisia species: a review. Phytotherapy research, 33(10), 2661-2684.

Mattos, G., Camargo, A., Sousa, C. A. & Zeni, A. L. B. (2018). Medicinal plants and herbal medicines in primary health care: the perception of the professionals. Ciência & Saúde Coletiva, 23(11), 3735-3744.

Minayo, M. C. S. (2014). O desafio do conhecimento: pesquisa qualitativa em saúde. (14a ed.), Hucitec-Abrasco.

Ministério da Saúde (BR). (2006a). Secretaria de Assistência à Saúde. Departamento de Atenção Básica. Política Nacional de Práticas Integrativas e Complementares no SUS: PNPIC-SUS. http://bvsms.saude.gov.br/bvs/publicacoes/politica_nacional_praticas_integrativas_complementares_2ed.pdf

Ministério da Saúde (BR). (2006b). Secretaria de Ciência, Tecnologia e Insumos Estratégicos. Departamento de Assistência Farmacêutica. Política Nacional de Plantas Medicinal e Fitoterápicos. http://bvsms.saude.gov.br/bvs/publicacoes/politica_nacional_fitoterapicos.pdf.

Niu, C. & Aisa, H. A. (2017). Upregulation of melanogenesis and tyrosinase activity: potential agents for Vitiligo. Molecules, 22(8), 1303.

Niu, C., Yin, L., Nie, L. F., Dou, J., Zhao, J. Y, Li, G. & Aisa, H. A. (2016). Synthesis and bioactivity of novel isoxazole chalcone derivatives on tyrosinase and melanin synthesis in murine B16 cells for the treatment of vitiligo. Bioorganic & medicinal chemistry, 24(21), 5440-5448.

Nonato, I. A., Viloria, M. I. V., Carvalho, G. D., Valente, F. L., Salcedo, J. H. P., Rosa, M. B. & Carvalho, C. A. (2018). Healing effects of formulations with extract of Sonchus oleraceus. Acta Scientiae Veterinariae, 46(1), 1605.

Oliveira, A.F.P., Costa, I.C.P., Andrade, C.G., Santos, K.F.O. & Anízio, B. K. F. (2017). Fitoterapia na atenção básica: estudo com profissionais enfermeiros. Revista online de Pesquisa Cuidado é Fundamental, 9(2), 480-487.

Pereira, A. S., Shitzuka, D. M., Parreira, F. J. &Shitzuka, R. (2018). Metodologia da pesquisa científica. UFSM.

Puri, A. V., Khandagale, P. D. & Ansari, Y. N. (2018). A review on ethnomedicinal, pharmacological and phytochemical aspects of Sonchus oleraceus linn. (Asteraceae). International Journal of Pharmacy and Biological Sciences, 8(3), 1-9.

Resende, J. H. C., Aquino, G. S. T., Nascimento, F. R. F., Aguiar, M. M. & Fiorelli, R. K. A. (2015). Oral use of an infusion of leaves of Solanum paniculatum L., Jacaranda brasiliensis and Sonchus oleraceus for treatment of vitiligo. Dermatological Sciences and Applications, 5, 317-331.

Rodríguez, M. A., Geertsma, I. P., Françozo, M. & Van, A. T. (2020). Marcgrave and piso's plants for sale: the presence of plant species and names from the história naturalis brasiliae (1648) in contemporary Brazilian markets. Journal of Ethnopharmacol, 7(1), 112911.

Salsberg, J. M., Weinstein, M., Shear, N., Lee, M. & Pope, E. (2016). Impact of cosmetic camouflage on the quality of life of children with skin disease and their families. Journal of cutaneous medicine and surgery, 20(3), 211-215.

Shah, B., Godse, K., Mahajan, S., Grandhi, S., Shendkar, S., Sharma, A., Teli, C., Pathak, R. & Parsad, D. (2019). Efficacy and safety of basic fibroblast growth factor (bFGF) related decapeptide solution plus Tacrolimus 0.1% ointment versus Tacrolimus 0.1% ointment in the treatment of stable vitiligo. Dermatologic therapy, 32(6), e13109.

Simons, R. E., Zevy, D. L. & Jafferany, M. (2020). Psychodermatology of vitiligo: psychological impact and consequences. Dermatologic Therapy, 33(3), e13418

Vallerand, I. A., Lewinson, R. T., Parsons, L. R., Hardin, J., Haber, R. M., Lowerison, M. W., Barnabe, C. & Patten S. B. (2019). Vitiligo and major depressive disorder: a bidirectional population-based cohort study. Journal of the American Academy of Dermatology, 80(5), 1371-1379.

Zeni, A. L. B., Parisotto, A. V., Mattos, G. & Helena, E. T. S. (2017). Use of medicinal plants as home remedies in primary health care in Blumenau – state of Santa Catarina, Brazil. Ciência & Saúde Coletiva, 22(8), 2703-2712.

Published

28/03/2021

How to Cite

EIBEL, G. S. B. .; ZILLY, A. .; SILVA, R. M. M. da .; FERREIRA, H. Use of the infusion of Sonchus oleraceus leaves for the treatment of vitiligo . Research, Society and Development, [S. l.], v. 10, n. 4, p. e1410413824, 2021. DOI: 10.33448/rsd-v10i4.13824. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/13824. Acesso em: 18 apr. 2024.

Issue

Section

Health Sciences