Possíveis tratamentos farmacológicos em fase de estudos para pacientes sintomáticos de COVID-19:Uma revisão integrativa
DOI:
https://doi.org/10.33448/rsd-v10i6.15579Palavras-chave:
Possíveis Tratamentos; COVID-19; Pandemia; Novo Coronavírus; SARS-CoV-2.Resumo
Objetivo: Realizar uma revisão integrativa sobre os possíveis tratamentos farmacológicos estudados atualmente como estratégias terapêuticas para pacientes COVID-19 positivos. Métodos: Foi realizada uma revisão integrativa de estudos da base de dados Medical Literature Analysis and Retrieval System, no sistema de busca PUBMED, na qual foram selecionados 58 artigos abordando 9 classes de fármacos. Resultados: A distribuição dos 58 artigos incluídos na revisão foi categorizada por fármaco abordado. Foram considerados tratamentos com melhoras significativas os que observaram redução de carga viral, redução do tempo de internação ou melhora clínica estatisticamente relevantes de acordo com os critérios de cada estudo. Conclusão: Com a urgência da produção rápida de resultados, foi observado que há uma grande dificuldade de produção de ensaios clínicos cego, duplo cego, fazendo com que a comunidade científica se restrinja principalmente a estudos retrospectivos e observacionais, que não são tão eficientes quanto os citados anteriormente. Com base na observação dos estudos, ainda não há um tratamento eficaz para a COVID-19, sendo crucial a aplicação de medidas preventivas, a fim de evitar o impacto da doença na população.
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Copyright (c) 2021 Danielle Guimarães Silva; Renan Tripode Bartaquini; Beatriz Moraes Pedrosa; Carolina Heitmann Mares Azevedo Ribeiro; Ana Cristina Lo Prete
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