O impacto do trabalho rotativo e noturno no contexto do câncer de mama e de próstata: uma revisão sistemática

Autores

DOI:

https://doi.org/10.33448/rsd-v10i12.20239

Palavras-chave:

Câncer de mama; Câncer de próstata; Trabalho noturno; Ritmo circadiano.

Resumo

Este trabalho tem o objetivo de verificar na literatura a relação entre o câncer e ao trabalho noturno e rotativo. Para isso, foi realizada uma pesquisa utilizando as bases de dados PUB MED, WEB OF SCIENCE, SCOPUS e LILACS, onde foram encontrados 649 estudos nos últimos 5 anos relacionados ao tema. Após passarem por alguns processos de exclusão, restaram apenas 23 estudos que correspondiam aos critérios da pesquisa. No presente trabalho foram analisados estudos de coorte, estudos de caso controle, estudos transversais e estudos experimentais, 15 desses estudos se tratavam de câncer de mama, 6 de câncer de próstata e 2 de ambos os cânceres. Foram destacados os enfermeiros como público principal das pesquisas. De acordo com os resultados desta revisão, foi sugerido que o trabalho noturno com interrupção do ritmo circadiano pode afetar e diminuir a síntese de melatonina, o que torna um fato preocupante visto que, níveis baixos de melatonina foi intimamente relacionada tanto ao câncer de mama quanto de próstata, e também foi classificada com importante função antitumoral. Outros possíveis fatores relacionados ao trabalho noturno e o câncer de mama é o encurtamento dos telômeros e hábitos de risco durante o período noturno. Diante dos possíveis riscos atribuídos a estes dois tipos cânceres, acredita-se que a cronoterapia e a suplementação a base melatonina seriam medidas importantes no processo de prevenção.

Referências

Åkerstedt, T. et al. (2015). Night Work and Breast Cancer in Women: A Swedish Cohort Study. Bmj Open, V. 5, N. 4, P. E008127. http://dx.doi.org/10.1136/bmjopen-2015-008127.

Åkerstedt, T. et al. (2017). Night Work and Prostate Cancer in Men: A Swedish Prospective Cohort Study. Bmj Open, V. 7, N. 6, P. E015751, http://dx.doi.org/10.1136/bmjopen-2016-015751.

Behrens, T. et al. (2017). Shift Work and The Incidence of Prostate Cancer: A 10-Year Follow-Up of A German Population-Based Cohort Study. Scandinavian Journal of Work, Environment & Health, V. 43, N. 6, P. 560-568, http://dx.doi.org/10.5271/sjweh.3666.

Carugno, M. et al. (2019). Night Shift Work, Dna Methylation and Telomere Length: An Investigation on Hospital Female Nurses. International Journal Of Environmental Research And Public Health, V. 16, N. 13, P. 2292, https://doi.org/10.3390/ijerph16132292.

Cordina-Duverger, E. et al. (2016). Night Work and Breast Cancer Risk Defined by Human Epidermal Growth Factor Receptor-2 (Her2) And Hormone Receptor Status: A Population-Based Case–Control Study in France. Chronobiology International, V. 33, N. 6, P. 783-787, https://doi.org/10.3109/07420528.2016.1167709.

Castro, T. B. et al. (2018). Evaluation Of Melatonin and Afmk Levels in Women with Breast Cancer. Endocrine, V. 62, N. 1, P. 242-249, http://doi.org/10.1007/s12020-018-1624-2.

Dickerman, B. A. et al. (2016). Sleep Disruption, Chronotype, Shift Work, And Prostate Cancer Risk and Mortality: A 30-Year Prospective Cohort Study Of Finnish Twins. Cancer Causes & Control, V. 27, N. 11, P. 1361-1370, http://doi.org/10.1007/s10552-016-0815-5.

Erdem, J. S. et al (2017). Mechanisms Of Breast Cancer in Shift Workers: Dna Methylation in Five Core Circadian Genes In Nurses Working Night Shifts. Journal Of Cancer, V. 8, N. 15, P. 2876, http://doi.org/10.7150/jca.21064.

Fang, M. Z. et al. (2015). Sleep Interruption Associated with House Staff Work Schedules Alters Circadian Gene Expression. Sleep Medicine, V. 16, N. 11, P. 1388-1394, https://doi.org/10.1016/j.sleep.2015.06.011.

Flynn-Evans, E. E. et al. (2014). Shiftwork And Prostate-Specific Antigen in The National Health And Nutrition Examination Survey. Journal Of The National Cancer Institute, V. 105, N. 17, P. 1292-1297, https://doi.org/10.1093/jnci/djt169.

Fritschi, L. et al. (2018). Shift Work That Involves Circadian Disruption and Breast Cancer: A First Application Of Chronobiological Theory And The Consequent Challenges. Occup Environ Med, V. 75, N. 3, P. 231-234, http://dx.doi.org/10.1136/oemed-2017-104441.

Garcia-Saenz, A. et al. (2018). Evaluating The Association Between Artificial Light-At-Night Exposure and Breast and Prostate Cancer Risk In Spain (Mcc-Spain Study). Environmental Health Perspectives, V. 126, N. 4, P. 047011, https://doi.org/10.1289/EHP1837.

Hammer, G. P. et al. (2015). Shift Work and Prostate Cancer Incidence in Industrial Workers: A Historical Cohort Study In A German Chemical Company. Deutsches Ärzteblatt International, V. 112, N. 27-28, P. 463, https://doi.org/10.3238/arztebl.2015.0463.

Jafri, M. A. et al. (2016). Roles Of Telomeres and Telomerase in Cancer, And Advances In Telomerase-Targeted Therapies. Genome Medicine, V. 8, N. 1, P. 69, https://doi.org/10.1186/s13073-016-0324-x.

Jones, M. E. et al. (2019). Night Shift Work and Risk of Breast Cancer In Women: The Generations Study Cohort. British Journal of Cancer, P. 1, https://doi.org/s41416-019-0485-7.

Li, W. et al. (2015). Shift Work and Breast Cancer Among Women Textile Workers In Shanghai, China. Cancer Causes & Control, V. 26, N. 1, P. 143-150, https://doi.org/10.1007/s10552-014-0493-0.

Morales-Santana, S. et al. (2019). An Overview of The Polymorphisms of Circadian Genes Associated With Endocrine Cancer. Frontiers In Endocrinology, V. 10, P. 104, https://doi.org/10.3389/fendo.2019.00104.

Papantoniou, K. et al. (20116). Breast Cancer Risk and Night Shift Work In A Case–Control Study In A Spanish Population. European Journal Of Epidemiology, V. 31, N. 9, P. 867-878, https://doi.org/10.1007/s10654-015-0073-y.

Papantoniou, K. et al. (2015). Night Shift Work, Chronotype and Prostate Cancer Risk In The Mcc‐S Pain Case‐Control Study. International Journal Of Cancer, V. 137, N. 5, P. 1147-1157, https://doi.org/10.1002/ijc.29400.

Pham, T. T. et al. (2019). Night-Shift Work and Risk of Breast Cancer In Korean Women. Clinical Epidemiology, V. 11, P. 743, https://doi.org/ 10.2147/CLEP.S199521.

Pham, T. T. et al. (2019). Night-Shift Work, Circadian and Melatonin Pathway Related Genes And Their Interaction On Breast Cancer Risk: Evidence From A Case-Control Study In Korean Women. Scientific Reports, V. 9, N. 1, P. 1-9, https://doi.org/s41598-019-47480-2.

Samulin, E. J. et al. (2017). Mechanisms Of Breast Cancer Risk in Shift Workers: Association Of Telomere Shortening With The Duration And Intensity Of Night Work. Cancer Medicine, V. 6, N. 8, P. 1988-1997, https://doi.org/10.1002/cam4.1135.

Son, H. Kang, Y. (2017). Breast Cancer Screening Among Shift Workers: A Nationwide Population-Based Survey In Korea. International Journal Of Occupational And Environmental Health, V. 23, N. 2, P. 94-97, https://doi.org/10.1080/10773525.2018.1425656.

Vistisen, H. T. et al. (2017). Short-Term Effects of Night Shift Work On Breast Cancer Risk: A Cohort Study Of Payroll Data. Scandinavian Journal Of Work, Environment & Health, V. 43, N. 1, P. 59-67, https://doi.org/10.5271/sjweh.3603.

Wang, P. et al. (2015). Night-Shift Work, Sleep Duration, Daytime Napping, And Breast Cancer Risk. Sleep Medicine, V. 16, N. 4, P. 462-468, https://doi.org/10.1016/j.sleep.2014.11.017.

Wendeu, F. Méyomo, G et al. (2018). Night Work and Prostate Cancer Risk: Results From The Epicap Study. Occup Environ Med, V. 75, N. 8, P. 573-581, https://doi.org/10.1136/oemed-2018-105009.

Downloads

Publicado

16/09/2021

Como Citar

LIMA, L. F. de .; CARVALHO, D. C. D. .; RODRIGUES, A. I.; SILVA, V. N. C. da .; NASCIMENTO, H. M. S. .; LIRA, J. A. S. P. de .; COELHO, F. A. da R. .; GOMES, P. R. C. .; COSTA, T. R. M. .; CASTRO, H. I. R. .; ALVES, E. H. P. .; OLIVEIRA, A. T. de . O impacto do trabalho rotativo e noturno no contexto do câncer de mama e de próstata: uma revisão sistemática. Research, Society and Development, [S. l.], v. 10, n. 12, p. e150101220239, 2021. DOI: 10.33448/rsd-v10i12.20239. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/20239. Acesso em: 23 nov. 2024.

Edição

Seção

Ciências da Saúde