Bisfosfonatos e suas indicações para prevenir a perda de densidade óssea na terapia contra o câncer

Autores

DOI:

https://doi.org/10.33448/rsd-v11i4.21577

Palavras-chave:

Fraturas por osteoporose; Osteoporose; Fraturas fechadas; Bone density conservation agents.

Resumo

Objetivo: Estabelecer um protocolo para pacientes medicados com bisfosfonatos, por meio de revisão da literatura, para evitar a osteonecrose e fornecer orientação profissional para a realização do tratamento adequado. Metodologia: Foram realizadas buscas on-line para a construção deste artigo, as quais incluíram como bases de dados Web of Science, PUBMED Central, BVS / BIREME, Science Direct, The Cochrane Library e também PROSPERO. Resultados: As seguintes características foram observadas na pesquisa deste protocolo: Medicamentos com propriedades antireabsorção, Inibidor de RANK-L, Agentes antiangiogênicos, Manifestações clínicas, Fatores de risco relacionados a medicamentos, Fatores de risco locais a serem observados, Fatores de risco sistêmicos e demográficos, Elevados fatores de risco considerados. Conclusões: Os bisfosfonatos podem ser uma terapia útil para pacientes com consequências orgânicas relacionadas à terapia aplicada com eles. Anamnese adequada e avaliação das condições sistêmicas dos pacientes que os utilizam são requisitos obrigatórios antes de sua prescrição.

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Publicado

18/03/2022

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OLIVEIRA, K. L. de A. M. de .; SILVA, L. B. .; SAMPAIO, G. M. .; CUNHA, R. S. C. .; SANTOS NETO, A. P. dos .; FONSECA, F. L. de M. A. .; MARQUES FILHO, E. de Q. .; FREITAS, W. J. L. .; ATAÍDE FILHO, A. C. de .; MAIA, S. S. . Bisfosfonatos e suas indicações para prevenir a perda de densidade óssea na terapia contra o câncer. Research, Society and Development, [S. l.], v. 11, n. 4, p. e27611421577, 2022. DOI: 10.33448/rsd-v11i4.21577. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/21577. Acesso em: 30 jun. 2024.

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