Utilidade da avaliação sérica e suplementação com vitamina D na clínica de cães e gatos: uma revisão
DOI:
https://doi.org/10.33448/rsd-v11i1.25175Palavras-chave:
Vitamina D; Prognóstico; Suplementação; Colecalciferol.Resumo
A vitamina D é tradicionalmente conhecida por seu papel na regulação da homeostase de cálcio e, consequentemente, manutenção da saúde óssea. No entanto, mais recentemente, têm-se observado que a mesma possui uma série de funções não-canônicas até então desconhecidas, desde sua participação na função do sistema imune até a manutenção da integridade da mucosa intestinal. Ademais, tem-se mostrado associada à progressão ou perpetuação de várias doenças, já que sua concentração sérica se encontra reduzida durante o quadro clínico destas. Por isso, buscamos investigar, por meio de revisão de literatura, a utilidade da mensuração sérica de vitamina D em cães e gatos como fator prognóstico de diferentes doenças sistêmicas, bem como o possível efeito terapêutico da suplementação desta vitamina na correção das enfermidades. De fato, a vitamina mostra-se deficiente em doenças gastroentéricas, como a enteropatia perdedora de proteínas, infecciosas, como a leishmaniose, cardiopatias e nefropatias, dentre outras. No entanto, é necessário que compreendamos mais o papel fisiológico da vitamina D na saúde, para que também o entendamos na doença. Também são escassos os dados que comprovem a utilidade da suplementação como terapia principal ou adjuvante no tratamento destas doenças, mas a mensuração sérica de vitamina D se mostra promissora como preditor prognóstico hospitalar para cães e gatos.
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