Óleos essenciais de espécies Lamiaceae com potencial atividade Anti-fúngica: uma revisão
DOI:
https://doi.org/10.33448/rsd-v11i2.25392Palavras-chave:
Fungos; Thymus; Lavandula; Origanum; Concentração inibitória mínima (MIC).Resumo
Nos últimos anos, a incidência de infecções fúngicas tem aumentado intensamente. As leveduras de Candida são responsáveis por uma ampla variedade de manifestações clínicas, desde infecções do trato urinário até infecções da corrente sanguínea. Uma alternativa aos medicamentos estão os óleos essenciais e seus compostos bioativos, os quais podem apresentar amplo espectro antimicrobiano. Existe uma grande quantidade de trabalhos na literatura que abordam a atuação de óleos essenciais de espécies vegetais como fontes potenciais de agentes antimicrobianos, incluindo a ação anti-Candida. As espécies de Lamiaceae são ricas em óleos essenciais, os quais apresentam substâncias promissores na inibição de Candida. Esta revisão levantou os artigos publicados nos últimos cinco anos (2016 a 2021) com as principais atividades anti-Candida dos óleos essências dos representantes de Lamiaceae, além de ressaltar seus componentes majoritários. A revisão constou de dados obtidos de 56 artigos os quais incluía 71 plantas de Lamiaceae. Os óleos essenciais das espécies mostraram boa atividade anti-Candida (CIMs <1000 µg/ mL). Os principais gêneros trabalhados foram: Thymus (14 artigos), Lavandula (7), Origanum (5) e Salvia (5). Os componentes majoritários encontrados nos óleos incluem timol (23 trabalhos), carvacrol (20), p-cimeno (17), linalol (10), 1,8-cineol (8), γ-terpineno (8) e α-pineno (8) como principais substâncias. Os óleos essenciais podem representar um importante achado no controle de fungos multirresistentes a medicamentos.
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Copyright (c) 2022 Denise Bezerra Correia; Dennis Bezerra Correia; Cícero Jorge Verçosa; Maria Eliana Vieira Figueroa; João Paulo Camilo de Oliveira; Allyson Francisco dos Santos; Nathália de Sousa Fernandes; Luiz Neldecílio Alves Vitor ; Francisco Diego Pereira; João Eudes Lemos de Barros; Elizângela Beneval Bento; Mayara Gonçalves Silva; Ginna Gonçalves Pereira; Cícero Leonardo Barbosa de Lima
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