Relação da coagulação intravascular disseminada pela determinação do dímero-D com a COVID-19: uma revisão integrativa
DOI:
https://doi.org/10.33448/rsd-v11i2.25731Palavras-chave:
COVID-19; Coagulação intravascular disseminada; Prognóstico.Resumo
A síndrome respiratória aguda grave causada pela COVID-19 foi recentemente relatada em Wuhan, capital da província chinesa de Hubei. A doença pode se manifestar de formas graves, em alguns desses casos, foram identificadas condições de hipercoagulabilidade seguido de alterações hematológicas. Este trabalho trata-se de uma revisão integrativa que avalia a relação da coagulação intravascular disseminada pela determinação do dímero-D com a COVID-19 e correlaciona esse marcador como um possível prognóstico da doença. Durante o estudo foi possível evidenciar que o aumento do dímero-D pode estar associado com uma maior gravidade da COVID-19 e/ou mortalidade, observada pelo aumento da ocorrência de CID, incluindo estudos em pacientes que evoluíram para quadros trombóticos, como TVP, TEV e embolia pulmonar. Além disso, tal associação em outras condições que aumentam a coagulação, como no caso de pacientes diabéticos tipo 2 e em pacientes que fizeram uso de ECMO.
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