Thalamic bilateral infarction: 2 cases reports

Authors

DOI:

https://doi.org/10.33448/rsd-v9i11.10380

Keywords:

Stroke; Thalamus; Ischemia; Cerebrovascular circulation.

Abstract

This study aimed to report two cases of bilateral thalamic infarction, one with mesencephalic involvement. The CARE checklist was used to report the two cases. First, (75-year-old) patient with a history of systemic arterial hypertension, had a sudden decrease in the level of consciousness (DLOC), a glasgow coma scale (GCS) 9, tetraparesis, paralysis of the third cranial nerve and left palpebral ptosis, anisocoria, absence of photomotor reflex and divergent strabismus (DS). CT showed hypodensity in the middle mesencephalic region and bilateral paramedian thalamic region. The treatment was conservative, with progress to improve the general condition, but without recovering of cranial nerve paralysis. In the second case, (38-year-old) patient, previously healthy, presented a sudden DLOC, dysarthria and GCS 13. Negative CT, while MRI showed hypersignal in the T2/FLAIR sequences, affecting the paramedian region of both thalamus with a predominance on the right. Conservative treatment was performed, evolving to significant improvement of the neurological condition. Although there is a typical presentation with disorders of mental status and ocular motricity, changes in CT may not be observed, reinforcing the need for attention to the sudden clinic presentation, so that new exams can be performed. It is important, therefore, to report these cases for the rapid diagnosis and appropriate treatment for a better prognosis of the patient.

References

Adams, H. P., Jr, Bendixen, B. H., Kappelle, L. J., Biller, J., Love, B. B., Gordon, D. L., & Marsh, E. E., 3rd (1993). Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke, 24(1), 35–41. https://doi.org/10.1161/01.str.24.1.35

Agarwal, S., Chancellor, B., & Howard, J. (2018). Clinical-radiographic correlates of Artery of Percheron infarcts in a case series of 6 patients. Journal of Clinical Neuroscience, 61, 266-268. doi: 10.1016/j.jocn.2018.11.030

Almeida, A. M. G. de, & Pereira, C. U. (2009). Hemorragia Talâmica Bilateral: Relato de Caso e Revisão de Literatura. Rev. bras. neurol. psiquiatr, 13(1), 33-35. Recuperado de https://www.revneuropsiq.com.br/rbnp/article/download/2/2

Arauz, A., Paino-Rodriguez, H. M., Vargas-Gonzalez, J. C., Arguelles-Morales, N., Silos, H., Ruiz-Franco, A., & Ochoa, M. C. (2014). Clinical spectrum of artery of Percheron infarct: clinical-radiological correlations. J Stroke Cerebrovasc Dis, 23(5), 1083–1088. doi: 10.1016/j.jstrokecerebrovasdis.2013.09.011

Caruso, P., Manganotti, P., & Moretti, R. (2016). Complex neurological symptoms in bilateral thalamic stroke due to Percheron artery occlusion. Vascular Health and Risk Management, 13, 11-14. doi: 10.2147/VHRM.S119395

Coradini, J. da S., Pereira, V. C., Machado, K. de F. C., Rangel, R. F., & Ilha, S. (2020). Protocolo clínico para acidente vascular cerebral: desenvolvimento de uma ferramenta de informação. Pesquisa, Sociedade e Desenvolvimento, 9 (6), e16963211. doi: https://doi.org/10.33448/rsd-v9i6.3211

GBD 2015 Mortality and Causes of Death Collaborators. (2016). Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet, 388(10053), 1459-1544. doi: https://doi.org/10.1016/S0140-6736(16)31012-1

Gibo, H., Lenkey, C., & Rhoton Jr, A. L. (1981). Microsurgical anatomy of the supraclinoid portion of the internal carotid artery. J Neurosurg, 55(4), 560-574. doi: 10.3171/jns.1981.55.4.0560

Kichloo, A., Jamal, S. M., Zain, E. A., Wani, F., & Vipparala, N. (2019). Artery of Percheron Infarction: A Short Review. Journal of Investigative Medicine High Impact Case Reports, 7, 1-6. doi: 10.1177/2324709619867355

Lazzaro, N. A., Wright, B., Castillo, M., Fischbein, N. J., Glastonbury, C. M., Hildenbrand, P. G., Wiggins, R. H., Quigley, E. P., & Osborn, A. G. (2010). Artery of Percheron infarction: imaging patterns and clinical spectrum. American Journal of Neuroradiology, 31(7), 1283–1289. doi: https://doi.org/10.3174/ajnr.A2044

Li, S., Kumar, Y., Gupta, N., Abdelbaki, A., Sahwney, H., Kumar, A., Mangla, M., & Mangla, R. (2018). Clinical and Neuroimaging Findings in Thalamic Territory Infarctions: A Review. J Neuroimaging, 28(4), 343-349. doi: 10.1111/jon.12503

Li, X., Agarwal, N., Hansberry, D. R., Prestigiacomo, C. J., & Gandhi, C. D. (2015). Contemporary therapeutic strategies for occlusion of the artery of Percheron: a review of the literature. J Neurointerv Surg, 7(2), 95-98. doi: 10.1136/neurintsurg-2013-010913.

Mello, G. A. M. de, Bridi, B. P. de L., Oliveira, D. G. de, & Jantsch, L. B. (2020). Prevalência de internações hospitalares por acidente vascular cerebral em crianças e adolescentes. Research, Society and Development, 9(7), e452974404. doi: https://doi.org/10.33448/rsd-v9i7.4404.

Párraga, R. G., Ribas, G. C., Andrade, S. E. G. L., & Oliveira, E. de. (2011). Microsurgical anatomy of the posterior cerebral artery in three-dimensional images. World Neurosurg, 75(2), 233-257. doi: 10.1016/j.wneu.2010.10.053

Qian, J., Wu, C., Peng, J., & Liu, H. (2017). Bilateral paramedian thalamic and midbrain infarction due to occlusion of the artery of percheron in an elderly male: a case report. Neurol Sci, 38(6), 1123-1126. doi: 10.1007/s10072-017-2860-6

Ranasinghe, T., Boo, S. H., & Adcock, A. (2019). Acute Onset of Hypersomnolence and Aphasia Secondary to an Artery of Percheron Infarct and a Proposed Emergency Room Evaluation. Case Reports in Emergency Medicine, 2019:1260865, 1-4. doi: 10.1155/2019/1260865

Riley, D. S., Barber, M. S., Kienle, G. S., Aronson, J. K., von Schoen-Angerer, T., Tugwell, P., Kiene, H., Helfand, M., Altman, D. G., Sox, H., Werthmann, P. G., Moher, D., Rison, R. A., Shamseer, L., Koch, C. A., Sun, G. H., Hanaway, P., Sudak, N. L., Kaszkin-Bettag, M., Carpenter, J. E., & Gagnier, J. J. (2017). CARE guidelines for case reports: explanation and elaboration document. J Clin Epidemiol. S0895-4356(17)30037-9. doi: 10.1016/j.jclinepi.2017.04.026.

Rhoton Jr., A. L. (2003). Rhoton cranial anatomy and surgical approaches. Philadelphia: Lippincott Williams & Wilkins.

Thomalla, G., Simonsen, C. Z., Boutitie, F, Andersen, G., Berthezene, Y., Cheng, B., Cheripelli, B., Cho, T., Fazekas, F., Fiehler, J., Ford, I., Galinovic, I., Gellissen, S., Amir, G., Gregori, J., Günther, M., Guibernau, J., Häusler, K. G., Hennerici, M., Kemmling, A., Marstrand, J., Modrau, B., Neeb, L., Ossa, N. P. de la, Puig, J., Ringleb, P., Roy, P., Scheel, E., Schonewille, W., Serena, J., Sunaert, S., Villringer, K., Wouters, A., Thijs, V., Ebinger, M., Endres, M., Fiebach, J.B., Lemmens, R., Muir, K.W., Nighoghossian, N., Pedraza, S., & Gerloff, C. (2018). MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset. New England Journal of Medicine, 379(7), 611–622. doi: 10.1056/NEJMoa1804355

Viticchi, G., Falsetti, L., Fiori, C., Jorio, G., Plutino, A., Buratti, L., Bartolini, M., & Silvestrini, M. (2016). Acute Occlusion of the Percheron Artery during Pregnancy: A Case Report and a Review of the Literature. Journal of Stroke and Cerebrovascular Diseases, 25(3), 572-7. doi: 10.1016/j.jstrokecerebrovasdis.2015.11.011

Zappella, N., Merceron, S., Nifle, C., Hilly-Ginoux, J., Bruneel, F., Troché, G., Cordoliani, Y., Bedos, J., Pico, F., & Legriel, S. (2014). Artery of Percheron infarction as an unusual cause of coma: three cases and literature review. Neurocritical care, 20(3), 494-501. doi: 10.1007/s12028-014-9962-2

Published

28/11/2020

How to Cite

MACHADO, V. P. .; COSTA, F. P. R. da .; BARBOSA JÚNIOR, L. .; SILVA, M. R. .; SANTOS, E. A. F. dos .; SILVA, A. V. . Thalamic bilateral infarction: 2 cases reports. Research, Society and Development, [S. l.], v. 9, n. 11, p. e59991110380, 2020. DOI: 10.33448/rsd-v9i11.10380. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/10380. Acesso em: 26 dec. 2024.

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Section

Health Sciences