Effect of a whitlockite glass-ceramic on the occlusion of dentinal tubules for dentin hypersensitivity treatment

Authors

DOI:

https://doi.org/10.33448/rsd-v10i3.13161

Keywords:

Biomaterials; Bioactive glass-ceramic; Dentin remineralization; 3CaO.P2O5-SiO2-MgO-system; Dentin hypersensitivity.

Abstract

A hipersensibilidade dentinária (HD) é caracterizada pela dor curta e aguda em resposta a estímulos externos, podendo ser tratada pela oclusão dos túbulos dentinários. Neste estudo, vidro original e uma vitrocerâmica do sistema 3CaO.P2O5-SiO2-MgO contendo whitlockita (fase de fosfato tricálcico substituído com Mg) foram avaliados quanto à eficácia no tratamento da HD. Um vidro bioativo com composição 52,75.(3CaO.P2O5)–30SiO2–17,25MgO (%p) foi tratado termicamente a 700°C e 775°C por 4 h. Terceiros molares humanos foram desmineralizados e distribuídos aleatoriamente em grupos: NT - controle negativo (sem tratamento), BG - controle positivo (tratado com Bioglass®45S5), GL - tratamento com vidro original e WGC - tratamento com whitlockita. Em seguida, amostras de dentina foram imersas em saliva artificial e armazenadas por 7 dias a 37ºC. Os biomateriais foram avaliados por Difração de Raios X (XRD) e Microscopia Eletrônica de Varredura (MEV). As amostras de dentina foram analisadas por MEV e ATR-FTIR, para identificar e quantificar variações composicionais na superfície dentinária. Foi identificada whitlockita como fase cristalina do GC, e sua presença leva à formação de partículas arredondadas, conforme mostrado por imagens de MEV. A análise de ATR-FTIR confirmou a formação de apatita na superfície de amostras BG, GL e WGC, o que foi corroborado pela oclusão dos túbulos dentinários, conforme imagens em MEV. As intensidades dos picos de infravermelho foram comparadas estatisticamente. Em relação à reatividade superficial pela análise semiquantitativa de FTIR, o GC demonstrou similaridade com o Bioglass®45S5 indicando que este material é promissor no tratamento de HD.

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Published

12/03/2021

How to Cite

JURASKI, A. de C.; FIGUEREDO, D. C.; DAGHASTANLI, N. A. .; SANTOS, C. dos .; FERNANDES, M. H. V. .; ANA, P. A. da .; DAGUANO, J. K. M. B. Effect of a whitlockite glass-ceramic on the occlusion of dentinal tubules for dentin hypersensitivity treatment. Research, Society and Development, [S. l.], v. 10, n. 3, p. e19610313161, 2021. DOI: 10.33448/rsd-v10i3.13161. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/13161. Acesso em: 17 apr. 2021.

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Engineerings