Efeito de um vitrocerâmico de whitlockite na oclusão dos túbulos dentinários para tratamento da hipersensibilidade dentinária
DOI:
https://doi.org/10.33448/rsd-v10i3.13161Palavras-chave:
Biomateriais; Vitrocerâmica bioativa; Remineralização da dentina; Sistema 3CaO.P2O5-SiO2-MgO; Hipersensibilidade dentinária.Resumo
Dentin hypersensitivity (DH) is characterized by short and sharp pain in response to external stimuli and can be treated by occluding dentinal tubules. In this study, a whitlockite (Mg-substituted tricalcium phosphate phase) glass-ceramic based on the 3CaO.P2O5-SiO2-MgO-system and its parent glass were evaluated on their effectiveness in treating DH. A bioactive glass with nominal composition 52.75(3CaO.P2O5)–30SiO2–17.25MgO (wt.%) was double-stage heat-treated at 700 °C and 775 °C for 4 h. Therefore, third molar human teeth were demineralized and randomly distributed into groups: NT – negative control (no treatment), BG – positive control (treated with Bioglass®45S5), GL – treatment with parent glass, and WGC – treatment with whitlockite glass-ceramic. Then, all the dentin samples were immersed in artificial saliva and stored for 7 days at 37 ºC. The biomaterials were evaluated by X-ray Diffraction (XRD) and Scanning Electron Microscopy (SEM). The dentin samples were analyzed by ATR-FTIR, to identify and quantify compositional variations on dentin surface, and by SEM. XRD identified whitlockite as the crystalline phase of GC and its presence leads to the formation of blunt particles, as shown by SEM images. ATR-FTIR analysis confirmed the formation of apatite compounds on the surface of all sample from BG, GL and WGC which was corroborated by the occlusion of dentinal tubules, as demonstrated by SEM images. Furthermore, the relative infrared peak intensities were compared statistically. Regarding surface reactivity by the semi-quantitative FTIR analysis, whitlockite GC demonstrated similarity to Bioglass®45S5 indicating that this material is promising for treating DH.
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Copyright (c) 2021 Amanda de Castro Juraski; Daniela Casimiro Figueredo; Nasser Ali Daghastanli; Claudinei dos Santos; Maria Helena Vaz Fernandes; Patrícia Aparecida da Ana; Juliana Kelmy Macário Barboza Daguano
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