Analysis of heart rate variability in people living with HIV undergoing antiretroviral therapy (TARV) after practicing physical activity




Physical exercise; Heart rate; AIDS serodiagnosis; Highly active antiretroviral therapy.


Acquired Immunodeficiency Syndrome (AIDS) is a disease caused by the Human Immunodeficiency Virus (HIV) that attacks the individual's defense cells, the TCD4 + lymphocytes causing a serious immune system disorder. Its treatment is based on therapy combined with antiretroviral medications that manage to control viral load and decrease the mortality rates of the disease. As an alternative, intervention strategies through the practice of physical exercises in order to assist in the treatment and quality of life of people living with HIV have been used for health benefits. This study aims to compare the heart rate variability (HRV) measured by a cardiofrequency meter, in HIV positive patients undergoing antiretroviral therapy (ART) at rest and after performing concurrent training (CT). The present study consists of an analytical, observational and cross-sectional research. The sample will consist of 15 people living with HIV and who are undergoing outpatient clinical follow-up at the Specialized Care Service (SAE) (Casa Rosa) in Barretos, in the interior of the state of São Paulo. To present the data, the Wilcoxon test was used to find which ones were different, the level of significance adopted was p <0.05. To verify the relationship of the results, Spearman's correlation coefficient test was used. The effect size was also calculated using the Cohen test (d). The analyzed data correlated the level of significance in all variables in the frequency and time domain, except for SDNN and SD2. There was a large effect size only for the parameter HF (Δ% = 279.92% reduction) in the frequency domain and in the parameters RMSSD (Δ% = 79.58% reduction) and SD1 (Δ% = 79.62% reduction) in the time domain in the TC, in the other parameters there was no great effect. Thus, one observes that the vagal resumption, which normally occurs after physical training, has not occurred or is returning slowly. While in the LF parameter there was a significant reduction, that is, a sympathetic withdrawal after the CT, even so, the sympathetic withdrawal was not total, since the parameter LF / HF (Δ% = 42.31% increase and TE = 0.70 ), that its increase means sympathetic activity, showed a significant increase after CT. In conclusion, the heart rate variability of the patients under study decreased after concurrent training, possibly due to the autonomic dysfunction shown in the literature for people living with HIV.


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How to Cite

GOIS , T. O. de; SANTOS, C. K. A. dos; ALVES, J. C. C.; DANTAS , E. H. M. Analysis of heart rate variability in people living with HIV undergoing antiretroviral therapy (TARV) after practicing physical activity. Research, Society and Development, [S. l.], v. 10, n. 6, p. e0610615436, 2021. DOI: 10.33448/rsd-v10i6.15436. Disponível em: Acesso em: 24 jun. 2021.



Health Sciences