Use of photodynamic therapy in the prevention and treatment of osteonecrosis of the jaw: an integrative literature review

Authors

DOI:

https://doi.org/10.33448/rsd-v11i5.28283

Keywords:

Osteonecrosis; Photodynamic therapy; Low-level light therapy; Bisphosphonate-associated osteonecrosis of the jaw.

Abstract

The aim of this study was to evaluate the use of photodynamic therapy (PDT) in the prevention and treatment of osteonecrosis of the jaw through an integrative literature review. Thus, a search was carried out in 8 scientific bases (MEDLINE, Cochrane Library, Scopus, ISI Web of Science, LILACS, BBO, SciELO and ClinicalTrials) using pre-established descriptors and search strategies, without language restrictions, date of publication and country where the study was carried out. Screening was carried out based on titles, abstracts and the full reading of studies by 2 evaluators, simultaneously and independently. The search identified 309 studies and 2 additional references were manually identified. After excluding duplicates, 236 studies were selected for analysis based on titles and abstracts, and 17 articles were fully read. After reading articles, 11 met the inclusion criteria and were included in this review. Among them, 8 are case reports or case series, 2 are in vivo studies with animal models and 1 was an in vitro study. It was observed that despite the diversity of protocols found, studies pointed out that PDT can be considered a supporting therapy useful in the prevention and treatment of osteonecrosis of the jaw. However, due to the absence of randomized clinical trials on the subject, it is suggested the development of further studies in order to have stronger scientific evidence and to more safely support the use of PDT in the treatment of osteonecrosis of the jaw.

References

AlDhalaan, N. A., BaQais, A., & Al-Omar, A. (2020). Medication-related Osteonecrosis of the Jaw: A Review. Cureus, 12(2), e6944. https://doi.org/10.7759/cureus.6944

Bermúdez-Bejarano, E. B., Serrera-Figallo, M. Á., Gutiérrez-Corrales, A., Romero-Ruiz, M. M., Castillo-de-Oyagüe, R., Gutiérrez-Pérez, J. L., & Torres-Lagares, D. (2017). Prophylaxis and antibiotic therapy in management protocols of patients treated with oral and intravenous bisphosphonates. Journal of clinical and experimental dentistry, 9(1), e141–e149. https://doi.org/10.4317/jced.53372

Castro M. S., Ribeiro N. V., Carli M. L., Pereira A. A. C., Sperandio F. F. & Hanemann J. A. C. (2016) Photodynamically dealing with bisphosphonate-related osteonecrosis of the jaw: Successful case reports. Photodiagnosis Photodyn Ther., 16, 72-75.

Ceponis, P., Keilman, C., Guerry, C., & Freiberger, J. J. (2017). Hyperbaric oxygen therapy and osteonecrosis. Oral diseases, 23(2), 141–151. https://doi.org/10.1111/odi.12489

Chambrone, L., Wang, H. L., & Romanos, G. E. (2018). Antimicrobial photodynamic therapy for the treatment of periodontitis and peri-implantitis: An American Academy of Periodontology best evidence review. Journal of periodontology, 89(7), 783–803. https://doi.org/10.1902/jop.2017.170172

Coelho, M. S., Vilas-Boas, L., & Tawil, P. Z. (2019). The effects of photodynamic therapy on postoperative pain in teeth with necrotic pulps. Photodiagnosis and photodynamic therapy, 27, 396–401. https://doi.org/10.1016/j.pdpdt.2019.07.002

Ervolino, E., Statkievicz, C., Toro, L. F., de Mello-Neto, J. M., Cavazana, T. P., Issa, J., Dornelles, R., de Almeida, J. M., Nagata, M., Okamoto, R., Casatti, C. A., Garcia, V. G., & Theodoro, L. H. (2019). Antimicrobial photodynamic therapy improves the alveolar repair process and prevents the occurrence of osteonecrosis of the jaws after tooth extraction in senile rats treated with zoledronate. Bone, 120, 101–113. https://doi.org/10.1016/j.bone.2018.10.014

Fliefel, R., Tröltzsch, M., Kühnisch, J., Ehrenfeld, M., & Otto, S. (2015). Treatment strategies and outcomes of bisphosphonate-related osteonecrosis of the jaw (BRONJ) with characterization of patients: a systematic review. International journal of oral and maxillofacial surgery, 44(5), 568–585. https://doi.org/10.1016/j.ijom.2015.01.026

Hafner, S., Ehrenfeld, M., Storz, E., & Wieser, A. (2016). Photodynamic Inactivation of Actinomyces naeslundii in Comparison With Chlorhexidine and Polyhexanide--A New Approach for Antiseptic Treatment of Medication-Related Osteonecrosis of the Jaw?. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 74(3), 516–522. https://doi.org/10.1016/j.joms.2015.09.014

Israel M. S., Antero S. A., Riche G. C., Pinheiro G. L., Meira M. L. D., & Heimlich F. V., et al. (2016). Photodynamic therapy for medication-related osteonecrosis of the jaws: a case report. Int J Clin Med., 7, 824-828. https://doi.org/10.4236/ijcm.2016.712089

Khan A. A., Morrison A., Hanley D. A., Felsenberg D., McCauley L. K., O'Ryan F., Reid I. R., Ruggiero S. L., Taguchi A., Tetradis S., Watts N. B., Brandi M. L., Peters E., Guise T., Eastell R., Cheung A. M., Morin S. N., Masri B., Cooper C., Morgan S. L., Obermayer-Pietsch B., Langdahl B. L., Al Dabagh R., Davison K. S., Kendler D. L., Sándor G. K., Josse R.G., Bhandari M., El Rabbany M., Pierroz D. D., Sulimani R., Saunders D. P., Brown J. P., Compston J. & International Task Force on Osteonecrosis of the Jaw (2015). Diagnosis and management of osteonecrosis of the jaw: a systematic review and international consensus. Journal of bone and mineral research, 30(1), 3–23. https://doi.org/ 10.1002/jbmr.2405

Li, F. L., Wu, C. B., Sun, H. J., & Zhou, Q. (2020). Effectiveness of laser-assisted treatments for medication-related osteonecrosis of the jaw: a systematic review. The British journal of oral & maxillofacial surgery, 58(3), 256–267. https://doi.org/10.1016/j.bjoms.2019.12.001

Lotufo, M. A., Tempestini Horliana, A., Santana, T., de Queiroz, A. C., Gomes, A. O., Motta, L. J., Ferrari, R., Dos Santos Fernandes, K. P., & Bussadori, S. K. (2020). "Efficacy of photodynamic therapy on the treatment of herpes labialis: A systematic review". Photodiagnosis and photodynamic therapy, 29, 101536. https://doi.org/10.1016/j.pdpdt.2019.08.018

Minamisako, M. C., Ribeiro, G. H., Lisboa, M. L., Mariela Rodríguez Cordeiro, M., & Grando, L. J. (2016). Medication-Related Osteonecrosis of Jaws: A Low-Level Laser Therapy and Antimicrobial Photodynamic Therapy Case Approach. Case reports in dentistry, 2016, 6267406. https://doi.org/10.1155/2016/6267406

Momesso, G., Lemos, C., Santiago-Júnior, J. F., Faverani, L. P., & Pellizzer, E. P. (2020). Laser surgery in management of medication-related osteonecrosis of the jaws: a meta-analysis. Oral and maxillofacial surgery, 24(2), 133–144. https://doi.org/10.1007/s10006-020-00831-0.

Mota, A. C. C., França, C. M., Prates, R., Deana, A. M., Costa Santos, L., Lopes Garcia, R., Leal Gonçalves, M. L., Mesquita Ferrari, R. A., Porta Santos Fernandes, K., & Kalil Bussadori, S. (2016). Effect of photodynamic therapy for the treatment of halitosis in adolescents - a controlled, microbiological, clinical trial. Journal of biophotonics, 9(11-12), 1337–1343. https://doi.org/10.1002/jbio.201600067

Poli, P. P., Souza, F. Á., & Maiorana, C. (2018). Adjunctive use of antimicrobial photodynamic therapy in the treatment of medication-related osteonecrosis of the jaws: A case report. Photodiagnosis and photodynamic therapy, 23, 99–101. https://doi.org/10.1016/j.pdpdt.2018.06.004

Poli, P. P., Souza, F. Á., Ferrario, S., & Maiorana, C. (2019). Adjunctive application of antimicrobial photodynamic therapy in the prevention of medication-related osteonecrosis of the jaw following dentoalveolar surgery: A case series. Photodiagnosis and photodynamic therapy, 27, 117–123. https://doi.org/10.1016/j.pdpdt.2019.05.037

Ribeiro, G. H., Chrun, E. S., Dutra, K. L., Daniel, F. I., & Grando, L. J. (2018). Osteonecrosis of the jaws: a review and update in etiology and treatment. Brazilian journal of otorhinolaryngoly, 84 (1), 102-8. https://doi.org/10.1016/j.bjorl.2017.05.008

Rugani, P., Acham, S., Kirnbauer, B., Truschnegg, A., Obermayer-Pietsch, B., & Jakse, N. (2015). Stage-related treatment concept of medication-related osteonecrosis of the jaw-a case series. Clinical oral investigations, 19(6), 1329–1338.

Rugani, P., Truschnegg, A., Acham, S., Kirn-Bauer, B. & Jakse, N. (2013) Use of photodynamic therapy in treatment of bisphosphonate-related osteonecrosis of the jaws: literature review and case series. J Anal Bioanal Tech, 1(6).

Ruggiero S. L. (2015). Diagnosis and Staging of Medication-Related Osteonecrosis of the Jaw. Oral and maxillofacial surgery clinics of North America, 27(4), 479–487. https://doi.org/10.1016/j.coms.2015.06.008

Ruggiero, S. L., Dodson, T. B., Fantasia, J., Goodday, R., Aghaloo, T., Mehrotra, B., O'Ryan, F., & American Association of Oral and Maxillofacial Surgeons (2014). American Association of Oral and Maxillofacial Surgeons position paper on medication-related osteonecrosis of the jaw--2014 update. Journal of oral and maxillofacial surgery: official journal of the American Association of Oral and Maxillofacial Surgeons, 72(10), 1938–1956. https://doi.org/10.1016/j.joms.2014.04.031.

Sánchez, M. D.P. R. Statkievicz, C., de Mello-Neto, J. M., Toro, L. F., Bassi, A., Garcia, V. G., Theodoro, L. H., & Ervolino, E. (2020). The Effectiveness of the Low-Level Laser, Antibiotic and Surgical Therapy in the Treatment of Medication-Related Osteonecrosis of the Jaws: A Case Report. Journal of lasers in medical sciences, 11(1), 98–103. https://doi.org/10.15171/jlms.2020.16

Sarkarat, F., Modarresi, A., Chiniforush, N., Yazdanparast, L., & Rakhshan, V. (2019). Efficacy of Photodynamic Therapy in Minimizing Bisphosphonate-Related Osteonecrosis of the Jaws After Dental Extraction: A Preliminary Animal Study. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 77(2), 307–314. https://doi.org/10.1016/j.joms.2018.09.036

Silva, L. F., Curra, C., Munerato, M. S., Deantoni, C. C., Matsumoto, M. A., Cardoso, C. L., & Curi, M. M. (2016). Surgical management of bisphosphonate-related osteonecrosis of the jaws: literature review. Oral and maxillofacial surgery, 20(1), 9–17. https://doi.org/10.1007/s10006-015-0538-x

Simões A., Benites B.M., Benassi C., Torres-Schroter G., de Castro J.R., & Campos L. (2017) Antimicrobial photodynamic therapy on treatment of infected radiation-induced oral mucositis: report of two cases. Photodiagnosis Photodyn Ther.,20, 18-20.

Tandon, S., Lamba, A. K., Faraz, F., Aggarwal, K., & Chowdhri, K. (2019). A case report of bisphosphonate related osteonecrosis of the jaw treated by photodynamic therapy. Photodiagnosis and photodynamic therapy, 26, 313–315. https://doi.org/10.1016/j.pdpdt.2019.04.017

Tardivo, J. P., Del Giglio, A., de Oliveira, C. S., Gabrielli, D. S., Junqueira, H. C., Tada, D. B., Severino, D., de Fátima Turchiello, R., & Baptista, M. S. (2005). Methylene blue in photodynamic therapy: From basic mechanisms to clinical applications. Photodiagnosis and photodynamic therapy, 2(3), 175–191. https://doi.org/10.1016/S1572-1000(05)00097-9

Tartaroti, N. C., Marques, M. M., Naclério-Homem, M., Migliorati, C. A., & Zindel Deboni, M. C. (2020). Antimicrobial photodynamic and photobiomodulation adjuvant therapies for prevention and treatment of medication-related osteonecrosis of the jaws: Case series and long-term follow-up. Photodiagnosis and photodynamic therapy, 29, 101651. https://doi.org/10.1016/j.pdpdt.2020.101651

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Published

04/04/2022

How to Cite

FERNANDES NETO, J. de A.; GOUVEIA, A. C. V. de; CATÃO, J. S. dos S. B.; FERREIRA, A. C. D.; FARIAS, L. G. de; SILVA, M. das G. B. da; SIMÕES, T. M. S.; LEMOS, Éverson de A.; CATÃO, M. H. C. de V. Use of photodynamic therapy in the prevention and treatment of osteonecrosis of the jaw: an integrative literature review . Research, Society and Development, [S. l.], v. 11, n. 5, p. e24611528283, 2022. DOI: 10.33448/rsd-v11i5.28283. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/28283. Acesso em: 22 dec. 2024.

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Health Sciences