Single Crystal of 1-(2'-hidroxyphenyl)-3-hidroxy-3-(4-methoxyphenil)-propan-1-one: Synthesis, structure and vibrational properties
DOI:
https://doi.org/10.33448/rsd-v11i9.31433Keywords:
Chalcones derivatives; Flavonoid synthesis; Flavonoids structure; Raman in flavonoids.Abstract
Chalcones, flavonoids, isoflavonoids and other derived substances have been extensively studied in recent years presenting various pharmacological activities and in some cases presenting very important physical properties such as non-linear optical properties (ONL). Recently it was observed that the compound 1-(2'-hydroxyphenyl)-3-hydroxy-3-(4-methoxyphenyl)-propan-1-one is an intermediate precursor in the biosynthesis of (2E)-1-(2-hydroxyphenyl) -3-(4-methoxyphenyl)prop-2-en-1-one, which is a compound belonging to the class of chalcones. After this observation, said precursor compound was crystallized in the laboratory and its crystal structure was identified by X-ray diffraction. The title compound was synthesized and crystallized from methanol in the centrosymmetric space group P21/c. The geometric parameters and supramolecular arrangement of the crystal structure obtained from single crystal X-ray diffraction data were analyzed. Furthermore, the vibrational properties were characterized by Raman spectroscopy. The attributions of the vibrational modes and detailed information of the synthesis are presented.
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Copyright (c) 2022 Heriberto Rodrigues Bitencourt ; José Ciriaco Pinheiro; Antônio Pedro da Silva Souza Filho; Sanclayton Geraldo Moreira; Alejandro Pedro Ayala; Cláudio Márcio Rocha Remédios
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