Efficacy of pelvic floor muscle training on the sexual function of men after radical prostatectomy: an overview of systematic reviews

Authors

DOI:

https://doi.org/10.33448/rsd-v11i11.33532

Keywords:

Prostatectomy; Erectile dysfunction; Rehabilitation; Pelvic floor disorders, male.

Abstract

This study aimed to evaluate the evidence in the literature on the efficacy of pelvic floor muscle training on the sexual function (SF) of men after prostatectomy by an overview of systematic reviews (SR) of randomized clinical trials. The search for studies was conducted in five databases without any language restriction: EMBASE, PUBMED, Science Direct, PEDro, and Cochrane Library. The main results were extracted from the SR by two reviewers, and meta-analysis was performed from the primary studies for the outcomes SF scores and erectile dysfunction. 4 reviews were included in the qualitative synthesis, which involved 8 clinical trials and 891 participants. The reviews had moderate to good methodological quality, but a high overlap of clinical studies was founded. Meta-analysis showed that pelvic floor muscle training improves sexual function scores not in 3 months (p=0.51) but in 6 months (p=0.02) and it did not show efficacy on erectile dysfunction after three (p=0.58) and 12 months (p=0.32). Studies with moderate to good methodological quality demonstrate that pelvic floor muscle training only improve sexual function score in 6 months, but not had efficacy in erectile dysfunction in men after prostatectomy.

References

Andrew R McCullough. (2005). Sexual function after radical prostatectomy. The Prostate, 7(2), 123–126. https://doi.org/10.1002/pros.2990080203

Barakat, B., Othman, H., Gauger, U., Wolff, I., Hadaschik, B., & Rehme, C. (2021). Retzius Sparing Radical Prostatectomy Versus Robot-assisted Radical Prostatectomy : Which Technique Is More Beneficial for Prostate Cancer Patients ( MASTER Study )? A Systematic Review and Meta-analysis. European Urology Focus, 21, 1–12. https://doi.org/10.1016/j.euf.2021.08.003

Bougioukas, K. I., Bouras, E., Apostolidou-Kiouti, F., Kokkali, S., Arvanitidou, M., & Haidich, A. B. (2019). Reporting guidelines on how to write a complete and transparent abstract for overviews of systematic reviews of health care interventions. Journal of Clinical Epidemiology, 106, 70–79. https://doi.org/10.1016/j.jclinepi.2018.10.005

Bougioukas, K. I., Liakos, A., Tsapas, A., Ntzani, E., & Haidich, A. B. (2018). Preferred reporting items for overviews of systematic reviews including harms checklist: a pilot tool to be used for balanced reporting of benefits and harms. Journal of Clinical Epidemiology, 93, 9–24. https://doi.org/10.1016/j.jclinepi.2017.10.002

Bray, F., Ferlay, J., Soerjomataram, I., Siegel, R. L., Torre, L. A., & Jemal, A. (2018). Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 68(6), 394–424. https://doi.org/10.3322/caac.21492

de Lira, G. H. S., Fornari, A., Cardoso, L. F., Aranchipe, M., Kretiska, C., & Rhoden, E. L. (2019). Effects of perioperative pelvic floor muscle training on early recovery of urinary continence and erectile function in men undergoing radical prostatectomy: A randomized clinical trial. International Braz J Urol, 45(6), 1196–1203. https://doi.org/10.1590/S1677-5538.IBJU.2019.0238

Feng, D., Tang, C., Liu, S., Yang, Y., Han, P., & Wei, W. (2020). Current management strategy of treating patients with erectile dysfunction after radical prostatectomy: a systematic review and meta-analysis. International Journal of Impotence Research, 378(9788), 328–337. https://doi.org/10.1038/s41443-020-00364-w

Geraerts, I., Van Poppel, H., Devoogdt, N., De Groef, A., Fieuws, S., & Van Kampen, M. (2016). Pelvic floor muscle training for erectile dysfunction and climacturia 1 year after nerve sparing radical prostatectomy: A randomized controlled trial. International Journal of Impotence Research, 28(1), 9–13. https://doi.org/10.1038/ijir.2015.24

Gilchrist, J. M. (2009). Weighted 2 × 2 kappa coefficients: recommended indices of diagnostic accuracy for evidence-based practice. Journal of Clinical Epidemiology, 62(10), 1045–1053. https://doi.org/10.1016/j.jclinepi.2008.11.012

Glazener, C., Boachie, C., Buckley, B., Cochran, C., Dorey, G., Grant, A., … N’Dow, J. (2011). Urinary incontinence in men after formal one-to-one pelvic-floor muscle training following radical prostatectomy or transurethral resection of the prostate (MAPS): two parallel randomised controlled trials. The Lancet, 378(9788), 328–337. https://doi.org/https://doi.org/10.1016/S0140-6736(11)60751-4

Heidenreich, A., Pfister, D., & Porres, D. (2015). Cytoreductive Radical Prostatectomy in Patients with Prostate Cancer and Low Volume Skeletal Metastases: Results of a Feasibility and Case-Control Study. The Journal of Urology, 193(3), 832–838. https://doi.org/https://doi.org/10.1016/j.juro.2014.09.089

Hodges, P., Stafford, R., Coughlin, G. D., Kasza, J., Ashton-Miller, J., Cameron, A. P., … Hall, L. M. (2019). Efficacy of a personalised pelvic floor muscle training programme on urinary incontinence after radical prostatectomy (MaTchUP): protocol for a randomised controlled trial. BMJ Open, 9, 28288. https://doi.org/10.1136/bmjopen-2018-028288

Hodges, P. W., Ph, D., Stafford, R. E., Ph, D., Hall, L., Ph, D., … D, M. (2019). Reconsideration of pelvic floor muscle training to prevent and treat incontinence after radical prostatectomy. Urologic Oncology: Seminars and Original Investigations, 000. https://doi.org/10.1016/j.urolonc.2019.12.007

Jarzemski, P., Brzoszczyk, B., Popiołek, A., Stachowicz-Karpińska, A., Golota, S., Bieliński, M., & Borkowska, A. (2019). Cognitive function, depression, and anxiety in patients undergoing radical prostatectomy with and without adjuvant treatment. Neuropsychiatric Disease and Treatment, 15, 819–829. https://doi.org/10.2147/NDT.S200501

Kannan, P., Winser, S. J., Choi Ho, L., Hei, L. C., Kin, L. C., Agnieszka, G. E., & Jeffrey, L. H. Y. (2019). Effectiveness of physiotherapy interventions for improving erectile function and climacturia in men after prostatectomy: a systematic review and meta-analysis of randomized controlled trials. Clinical Rehabilitation, 33(8), 1298–1309. https://doi.org/10.1177/0269215519840392

Laurienzo, C. E., Magnabosco, W. J., Jabur, F., Faria, E. F., Gameiro, M. O., Sarri, A. J., … Amaro, J. L. (2018). Pelvic floor muscle training and electrical stimulation as rehabilitation after radical prostatectomy: a randomized controlled trial. Journal of Physical Therapy Science, 30(6), 825–831. https://doi.org/10.1589/jpts.30.825

Lin, Y. H., Yu, T. J., Lin, V. C. H., Wang, H. P., & Lu, K. (2012). Effects of early pelvic-floor muscle exercise for sexual dysfunction in radical prostatectomy recipients. Cancer Nursing, 35(2), 106–114. https://doi.org/10.1097/NCC.0b013e3182277425

Milios, J. E., Ackland, T. R., & Green, D. J. (2020). Pelvic Floor Muscle Training and Erectile Dysfunction in Radical Prostatectomy: A Randomized Controlled Trial Investigating a Non-Invasive Addition to Penile Rehabilitation. Sexual Medicine, 8(3), 414–421. https://doi.org/10.1016/j.esxm.2020.03.005

Nicolai, M., Urkmez, A., Sarikaya, S., Fode, M., & Falcone, M. (2021). Penile Rehabilitation and Treatment Options for Erectile Dysfunction Following Radical Prostatectomy and Radiotherapy : A Systematic Review. Frontiers in Surgery, 8(March). https://doi.org/10.3389/fsurg.2021.636974

Oh, J. J., Kim, J. K., Lee, H., Lee, S., Jin Jeong, S., Kyu Hong, S., … Byun, S. S. (2020). Effect of personalized extracorporeal biofeedback device for pelvic floor muscle training on urinary incontinence after robot-assisted radical prostatectomy: A randomized controlled trial. Neurourology and Urodynamics, 39(2), 674–681. https://doi.org/10.1002/nau.24247

Perez, F. S. B., Rosa, N. C., da Rocha, A. F., Peixoto, L. R. T., & Miosso, C. J. (2018). Effects of biofeedback in preventing urinary incontinence and erectile dysfunction after radical prostatectomy. Frontiers in Oncology, 8(February), 1–10. https://doi.org/10.3389/fonc.2018.00020

Pieper, D., Antoine, S. L., Mathes, T., Neugebauer, E. A. M., & Eikermann, M. (2014). Systematic review finds overlapping reviews were not mentioned in every other overview. Journal of Clinical Epidemiology, 67(4), 368–375. https://doi.org/10.1016/j.jclinepi.2013.11.007

Prota, C., Gomes, C. M., Ribeiro, L. H. S., De Bessa, J., Nakano, E., Dall’oglio, M., … Srougi, M. (2012). Early postoperative pelvic-floor biofeedback improves erectile function in men undergoing radical prostatectomy: A prospective, randomized, controlled trial. International Journal of Impotence Research, 24(5), 174–178. https://doi.org/10.1038/ijir.2012.11

Rosen, R., Cappelleri, J., Smith, M., Lipsky, J., & Peña, B. (1999). Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction. International Journal of Impotence Research, 11(6), 319–326. https://doi.org/10.1038/sj.ijir.3900472

Schünemann, H., Brożek, J., Guyatt, G., & Oxman, A. (Eds.). (2013). GRADE handbook for grading quality of evidence and strength of recommendations. (Updated Oc). The GRADE Working Group. Retrieved from guidelinedevelopment.org/handbook

Shea, B. J., Reeves, B. C., Wells, G., Thuku, M., Hamel, C., Moran, J., … Henry, D. A. (2017). AMSTAR 2 : a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions , or both, 1–9. https://doi.org/10.1136/bmj.j4008

Wong, C., Louie, D. R., & Beach, C. (2020). A Systematic Review of Pelvic Floor Muscle Training for Erectile Dysfunction After Prostatectomy and Recommendations to Guide Further Research. Journal of Sexual Medicine, 17(4), 737–748. https://doi.org/10.1016/j.jsxm.2020.01.008

Downloads

Published

21/08/2022

How to Cite

XAVIER, M. A. de O.; JESUS, N. T. de .; DANTAS, D. de S. . Efficacy of pelvic floor muscle training on the sexual function of men after radical prostatectomy: an overview of systematic reviews. Research, Society and Development, [S. l.], v. 11, n. 11, p. e221111133532, 2022. DOI: 10.33448/rsd-v11i11.33532. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/33532. Acesso em: 28 sep. 2022.

Issue

Section

Health Sciences