Evidence about the imbalance of serotonin, vitamin D and melatonin in people with Autism Spectrum Disorder
DOI:
https://doi.org/10.33448/rsd-v11i12.34865Keywords:
Autism spectrum disorder; Serotonin; Vitamin D; Melatonin.Abstract
Autism Spectrum Disorder (ASD) represents a diverse group of conditions related to neurodevelopment, affecting one in every 100 children in the world, being prevalent in males. The main characteristics are the difficulty with social interaction and communication, in addition to repetitive and restrictive behaviors. The diagnosis can be made between 18 and 24 months of age, when characteristic symptoms can be distinguished from the child's typical development. It is noted that serotonin becomes important in ASD studies, which indicate that approximately 45% of patients have high serum levels of 5-HT and, consequently, less social interest. Furthermore, hypovitaminosis, also known as vitamin D deficiency, is related to ASD as well as melatonin deficiency. Therefore, the imbalance of serotonin, vitamin D and melatonin levels in patients diagnosed with ASD are of great relevance in terms of well-being and global health of the individual, due, respectively, to inference in social relationships, disorders neural pathways, as well as significant changes in the circadian cycle. Furthermore, it is feasible to observe that these particularities of patients with Autism Spectrum Disorder are of paramount importance in terms of early diagnosis, as well as effective treatment without external pharmacological measures. However, this is not yet a current reality.
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Copyright (c) 2022 Amanda Káren Alves Pereira; Bárbara Queiroz de Figueiredo; Eduarda Canedo Nogueira; Luana Damaceno Miranda; Natália Paniágua de Andrade; Lorrany Silva Nascimento
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