Rolandic Epilepsy: A literature review
DOI:
https://doi.org/10.33448/rsd-v13i2.45079Keywords:
Rolandic Epilepsy; Childhood epilepsy; Child neurodevelopment; Convulsive crises; Electroencephalogram; Antiepileptics; Pediatrics.Abstract
Epilepsy is a medical condition in which there is disturbance of brain activity, characterized by focal, unprovoked or reflex seizures. The objective was to discuss the diagnosis and evolution of Rolandic Epilepsy in childhood, syndromic characteristics and pharmacological therapeutic options. Material and method: integrative literature review using the SCIELO, PUBMED and UPTODATE databases, between 2012 and 2022. 69 articles were identified, being 22 used in the preparation of the work. The results show that Rolandic Epilepsy is the most common neurological disorder in childhood, among other epileptic syndromes, males are the most prevalent and the first manifestation usually occurs before puberty, between seven and nine years of age. The evolution of the clinical history helps in early diagnosis, which represents the best strategy to indicate the correct treatment and avoid future complications of childhood neurodevelopment. For this, the specific test is the electroencephalogram, the result of which reveals obvious abnormalities such as sharp centrotemporal waves and abnormal morphological findings. The prognosis for Rolandic Epilepsy is favorable, due to the self-limited nature of the disease; in most cases, seizures remit before adulthood without causing major damage to the child's neurological development.
References
Alfstad, K. Å., Torgersen, H., Van Roy, B., Hessen, E., Hansen, B. H., Henning, O., Clench-Aas, J., Mowinckel, P., Gjerstad, L., & Lossius, M. I. (2016). Psychiatric comorbidity in children and youth with epilepsy: An association with executive dysfunction? Epilepsy & behavior 56(1), 88–94. https://doi.org/10.1016/j.yebeh.2016.01.007
Berl, M. M., Terwilliger, V., Scheller, A., Sepeta, L., Walkowiak, J., & Gaillard, W. D. (2015). Speed and complexity characterize attention problems in children with localization-related epilepsy. Epilepsia, 56(6), 833–840. https://doi.org/10.1111/epi.12985
Binnie, C. D., Rowan, A. J., Overweg, J., Meinardi, H., Wisman, T., Kamp, A., Silva, F. L. (2015). Telemetric EEG and video monitoring in epilepsy. Neurology, 31(3), 298-303. https://doi.org/10.1212/wnl.31.3.298
Carvill, G. L., Regan, B. M., Yendle, S. C., Roak, B. J., Lozovaya, N. Bruneua, N., Bursnashev, N., Khan, A., Cook, J., Geraghty, E., Sadleir, L. G., Turner, S. J., Tsai, M. H., Werster, R., Ouvrier, R., Damiano, J. A., Berkovic, S. F., Shendure, J., Hildebrand, M. S., Szepetowski, P., Scheffer, I. E., & Mefford, H. C. (2013) GRIN2A mutations cause epilepsy-aphasia spectrum disorders. Nat Genet, 45(9), 23-45. https://doi.org/10.1038/ng.2727
Caraballo, R. H., Veggiotti, P., Kaltenmeier, M. C., Piazza, E., Gamboni, B., Avaria, M. F. L., Noli, D., Adi, J., & Cersosimo, R. (2013) Encephalopathy with status epilepticus during sleep or continuous spikes and waves during slow sleep syndrome: a multicenter, long-term follow-up study of 117 patients. Epilepsy Res, 105(2), 73-164. https://doi.org/10.1016/j.eplepsyres.2013.02.010
Carvalho, F. C., Camargo, C. C., Barbosa, T. P., Silva, M. N., Reis, M. B., Ferreira, L. C. E., Castro, L. K. C., & Sabatini, P. M. O. (2022). Epilepsia, do diagnóstico ao tratamento: revisão de literatura Epilepsy, from diagnosis to treatment: a literature review. Brazilian Journal of Development, 8(2), 8988-8997. https://doi.org/10.34117/bjdv8n2-038
Cavalcante, L. T, C., & Oliveira, A. A. S. (2020). Métodos de revisão bibliográfica nos estudos científicos. Psicol. rev. (Belo Horizonte), 26(1), p. 83-102.
Chen, X. Q., Zhang, W. N., Yang, Z. X., Zhao, M., Cai, F. C., Huang, S. P., Gao, L., Pang, B. D., Chen, X., & Zou, L. P. (2014). Efficacy of levetiracetam in electrical status epilepticus during sleep of children: a multicenter experience. Pediatr Neurol, 50(3), 240-243. https://doi.org/10.1016/j.pediatrneurol.2013.10.015
Ciumas, C., Saignavongs, M., Ilski, F., Herbillon, V., Laurent, A., Lothe, A., & Ryvlin, P. (2014) White matter development in children with benign childhood epilepsy with centro-temporal spikes. Brain, 137(4), 1095–1106. http://doi.org/10.1093/brain/awu039.
Costa, L. L. O., Brandão, E. C., & Segundo, L. M. (2020) Atualização em epilepsia: revisão de literatura. Revista de Medicina, 9(2), 170-181.
Dinkelacker, V., Xin, X., Baulac, M., Samson, S. & Dupont, S. (2016). Interictal epileptic discharge correlates with global and frontal cognitive dysfunction in temporal lobe epilepsy. Epilepsy & Behavior, 62(1), 197-203. https://doi.org/10.1016/j.yebeh.2016.07.009
Dimassi, S., Labalme, A., Lesca, G., Rudolf, G., Bruneau, N., Hirsch, E., Arzimanoglou, A., Motte, J., de Saint Martin, A., Boutry-Kryza, N., Cloarec, R., Benitto, A., Ameil, A., Edery, P., Ryvlin, P., De Bellescize, J., Szepetowski, P., & Sanlaville, D. (2014). A subset of genomic alterations detected in rolandic epilepsies contains candidate or known epilepsy genes including GRIN2A and PRRT2. Epilepsia, 55(2), 370–378. https://doi.org/10.1111/epi.12502
Ferreira, D. C. L. (2016) Memória operacional e consciência fonológica em crianças com epilepsia rolândica. Dissertação de Mestrado em Psicologia - Centro de Ciências Humanas, Letras e Artes, Universidade Federal do Rio Grande do Norte, 1(1), 67-69.
Filippini, M., Ardu, E., Stefanelli, S., Boni, A., Gobbi, G., & Benso, F. (2016). Neuropsychological profile in new onset benign epilepsy with centrotemporal spikes (BECTS): Focusing on executive functions. Epilepsy & Behavior, 54(1), 71-79. https://doi.org/10.1016/j.yebeh.2015.11.010
Koepp, M. T., Caciagli, L., Pressler, R. M., Lehnertz, K., & Beniczky, S. (2016) Reflex seizures, traits, and epilepsies: from physiology to pathology. Lancet Neurol, 15(1), 92-105. https://doi.org/10.1016/S1474-4422(15)00219-7
Lemke, J. R., Lal, D., Reinthaler, E. M., Steiner, I., Nothnagel, M., Alber, M., Geider, K., Laube, B., Schwake, M., Finsterwalder, K., Franke, A., Schilhabel, M., Jähn, J. A., Muhle, H., Boor, R., Van Paesschen, W., Caraballo, R., Fejerman, N., Weckhuysen, S., De Jonghe, P., & Spiczak, S. (2013). Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes. Nature genetics, 45(9), 1067–1072. https://doi.org/10.1038/ng.2728
Pereira, F. C., & Miranda, C. V. (2018) Epilepsia infantil: uma revisão bibliográfica. Repositório Institucional da Famp, 1(1), 12-13.
Sánchez, F. I., Peters, J. M., An, S., Bergin, M. A., Takeoka, M., Rotenberg, A., Kothare, S. V., Riviello, J. J., & Loddenkemper, T. (2013) Long-term response to high-dose diazepam treatment in continuous spikes and waves during sleep. Pediatr Neurol, 49(3), 163-170. https://doi.org/10.1016/j.pediatrneurol.2013.04.027
Sánchez, F. I., Chapman, K. E., Peters, J. M., Harini, C., Rotenberg, A., & Loddenkemper, T. (2013) Continuous Spikes and Waves during Sleep: Electroclinical Presentation and Suggestions for Management. Epilepsy Res Treat, 23(1), 133-145. https://doi.org/10.1155/2013/583531
Silva, C. R. A., Cardoso, I. S. Z., & Machado, N. R. (2013) Considerações sobre a Epilepsia. Boletim Científico de Pediatria, 2(3), 55-58.
Turner, S. J., Mayes, A. K., Verhoeven, A., Mandelstam, S. A., Morgan, A. T., & Scheffer, I. E. (2015) GRIN2A: an aptly named gene for speech dysfunction. Neurology, 84(6), 94-99. https://doi.org/10.1212/wnl.0000000000001228.
Wirrell, E. C., Nabbout, R., Scheffer, I. E., Alsaadi, T., Bogacz, A., French, J. A., Hirsch, E., Jain, S., Kaneko, S., Riney, K., Samia, P., Snead, C., Somerville, E., Specchio, N., Trinka, E., Balestrini, S., Wiebe, S., Cross, J. H., Perucca, E., Moshé, S. L., Tinuper, P., & Zuberi, S. M. (2022) Methodology for classification and definition of epilepsy syndromes with list of syndromes: Report of the ILAE Task Force on Nosology and Definitions. Epilepsia, 63(6), 1333-1348. https://doi.org/10.1111/epi.17237
Zaninotto, A. L. C., & Hamad, A. P. (2012) Características neurológicas e neuropsicológicas na epilepsia rolândica. Psicol. Hosp., 10(1), 68-79.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Mikaellem Nogueira dos Santos; Bruna Heduarda de Rezende; Daniela Luiz Nery; Fernanda de Rezende; Amanda Ferreira Barbosa; Laura Vitória de Lima Silva; Marciana Gomes de Sousa; Benedito Domingos Amorim Filho
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
