Association of demographic and clinical factors with sepsis severity and outcome




Sepsis; Shock septic; Hyperlactatemia; Protocols.


Objective: To analyze the association of demographic, clinical factors and lactate levels, with the severity and outcome of sepsis. Method: A cohort study, involving 1184 patients from a university hospital in Porto Alegre / Rio Grande do Sul, Brazil. Data collection took place through active search and medical records of patients with sepsis, from 2013 to 2015. Result: 59.7% (707) came from the emergency, with 2.0 ± 1.39 comorbidities due to with a similar distribution between men and women. Sepsis affected most of the patients, but mostly for septic shock, with respiratory as the main focus. Serum lactate levels (greater than 4 mmol / l) resulted in higher mortality and less than 6% had the lactate recovered until the sixth hour. Conclusion: Demographic and clinical factors that were associated with severity and outcomes were the origin and lactate collection in up to 3 hours. Lactate once again showed that it is an important marker of severity for septic patients, it should not be a marker used only in septic shock, but in cases of suspected sepsis. Sepsis care is of fundamental importance from diagnosis to treatment.


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How to Cite

OLIVEIRA , V. M. de .; LEWIS, M. L. .; MORETTI , M. M. S. .; NASCIMENTO, A. P. do .; LOBO, L. G. .; URBANETTO, J. de S. . Association of demographic and clinical factors with sepsis severity and outcome. Research, Society and Development, [S. l.], v. 9, n. 9, p. e778997759, 2020. DOI: 10.33448/rsd-v9i9.7759. Disponível em: Acesso em: 26 may. 2024.



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