Routine laboratory parameters of newly diagnosed pulmonary tuberculosis patients: a single center study in Brazil

Authors

DOI:

https://doi.org/10.33448/rsd-v9i11.9873

Keywords:

Diagnostic imaging; Water-electrolyte imbalance; Mycobacterium tuberculosis; Neutrophil; Signs and symptoms.

Abstract

Objective: Evaluate the severity of tuberculosis and its association with laboratory tests before antituberculosis treatment. Methodology: Patients with pulmonary tuberculosis were evaluated for severity using data available in medical records (Clinical; Excretion of mycobacteria; and Diagnostic imaging) and associated with biochemical and hematological parameters requested at the time of diagnosis and before antituberculosis treatment. Results: The evaluation of the severity showed a predominance of smear AFB (+), fever associated with other symptoms and infiltrative tuberculosis. Only a positive correlation between mycobacteria excretion and imaging diagnosis (rho=0.47; p=0.023) was observed. The patients presented hyponatremia (9/21), hypomagnesemia (6/13), and hypercalcemia (1/13), unrelated to the severity. The presence of fever influenced the number of non-segmented neutrophils (p=0.0142) and the total leukocyte count correlated with the increase in total neutrophils (rho=0.9631; p<0.0001). Conclusion: Different severity characteristics of tuberculosis, although they reflect the degree of commitment of the patient, are not always correlated; the evaluation of electrolytes could contribute to clinical behavior; and non-segmented neutrophils are associated with a worse clinical prognosis in patients with tuberculosis.

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Published

12/11/2020

How to Cite

BIADOLA, A. P. .; CORREA, A. A. dos S. .; AGUIAR, A. A. S. de .; ROSA, U. G. C. .; MAZARO, P. J. M. .; HÚNGARO, C. M. .; RODRIGUES, M. V. P. .; PERESI-LORDELO, E. Routine laboratory parameters of newly diagnosed pulmonary tuberculosis patients: a single center study in Brazil. Research, Society and Development, [S. l.], v. 9, n. 11, p. e2559119873, 2020. DOI: 10.33448/rsd-v9i11.9873. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/9873. Acesso em: 19 apr. 2024.

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Vol. 9 No. 11

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Health Sciences

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Copyright (c) 2020 Ana Paula Biadola; André Aparecido dos Santos Correa; Amanda Aparecida Silva de Aguiar; Ualter Guilherme Cipriano Rosa; Paulo José Mascarenhas Mazaro; Christiane Martinez Húngaro; Marcus Vinícius Pimenta Rodrigues; Eliana Peresi-Lordelo

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