Routine laboratory parameters of newly diagnosed pulmonary tuberculosis patients: a single center study in Brazil




Diagnostic imaging; Water-electrolyte imbalance; Mycobacterium tuberculosis; Neutrophil; Signs and symptoms.


Objective: Evaluate the severity of tuberculosis and its association with laboratory tests before antituberculosis treatment. Methodology: Patients with pulmonary tuberculosis were evaluated for severity using data available in medical records (Clinical; Excretion of mycobacteria; and Diagnostic imaging) and associated with biochemical and hematological parameters requested at the time of diagnosis and before antituberculosis treatment. Results: The evaluation of the severity showed a predominance of smear AFB (+), fever associated with other symptoms and infiltrative tuberculosis. Only a positive correlation between mycobacteria excretion and imaging diagnosis (rho=0.47; p=0.023) was observed. The patients presented hyponatremia (9/21), hypomagnesemia (6/13), and hypercalcemia (1/13), unrelated to the severity. The presence of fever influenced the number of non-segmented neutrophils (p=0.0142) and the total leukocyte count correlated with the increase in total neutrophils (rho=0.9631; p<0.0001). Conclusion: Different severity characteristics of tuberculosis, although they reflect the degree of commitment of the patient, are not always correlated; the evaluation of electrolytes could contribute to clinical behavior; and non-segmented neutrophils are associated with a worse clinical prognosis in patients with tuberculosis.


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How to Cite

Biadola, A. P. ., Correa, A. A. dos S. ., Aguiar, A. A. S. de ., Rosa, U. G. C. ., Mazaro, P. J. M. ., Húngaro, C. M. ., Rodrigues, M. V. P. ., & Peresi-Lordelo, E. (2020). Routine laboratory parameters of newly diagnosed pulmonary tuberculosis patients: a single center study in Brazil. Research, Society and Development, 9(11), e2559119873.



Health Sciences