Panorama of congenital syphilis in school hospital of the hospital of the South region of city of São Paulo
DOI:
https://doi.org/10.33448/rsd-v10i4.13952Keywords:
Congenital syphilis; Newborn at risk; Public health; Epidemiology.Abstract
Introduction: Congenital syphilis is an infectious disease that has the etiological agent Treponema pallidum. Its transmission is vertical hematogenous, transplacental, of infected pregnant untreated or inadequately treated for its concept. It divides into two periods: early to the second year of life, and after the second year of life, late. Detection during prenatal care is performed by screening the third trimester of pregnancy with preterm labor, as early as in the maternity ward. The detection of Treponema pallidum through non-treponemal test (VDRL), presents little specificity, high sensitivity, low cost and fast negativation in response to the treatment avoiding that the concept is born with sequels. Thus, prenatal care is an important tool in the control of the disease, and it is necessary to improve care quality, since 70% of the mothers in Brazil are prenatal, not all of them are diagnosed or have the appropriate treatment of syphilis. Objective: To establish an epidemiological panorama of the incidence of Congenital Syphilis in the socioeconomic and cultural context in which the School Hospital of the Southern Region of the city of São Paulo is inserted. Patients and Methods: This is an individualized, observational, cross-sectional study carried out by means of a medical records survey of the Hospital Infection Control Service of Hospital Escola da Região Sul in the city of São Paulo. The survey of data referring to the form with questions of interest to the mother and the newborns diagnosed with Congenital Syphilis in the period from 2012 to 2016 was developed. This project was submitted and approved by the Ethics Committee of the Santo Amaro University - SP (Plataforma Brasil - CAAE: 68103317.6.3001.5447). Results: A total of 183 cases of Congenital Syphilis were registered in the Hospital Infection Control Service of the São Paulo School Hospital from 2012 to 2016, and among these, 126 medical records were reinforced. Prenatal performance (p = 0.0060), schooling (p = 0.5107) and schooling (p = 0.8603) did not influence disease screening by showing insignificant statistical data. Success occurred with companion treatment (p = 0.0451), which showed the highest incidence in 2014 (48.1%) and 2016 (58.3) when compared to the others. Conclusion: In the presented scenario, it was verified that although prenatal and maternal treatment were performed, they were inefficient to prevent pregnant women from transmitting the disease. This is probably related to the inefficiency of the treatment of the companions, who although in the year 2014 and 2016 presented a higher incidence of accomplishment, coincided with the increase of notifications in those same years. There were no statistically significant differences in relation to other factores, a fact that causes concern in the field of Public Health.
References
Araujo, E. C.; & Gama, K. S.; Azevedo, R. S.; & Gama, V. N. L.; & Souto, F. A. (2006) The importance of prenatal care in the prevention of Congenital Syphilis. Rev. Paraense de Medicina.
Brasil. (2017). Ministério da Saúde. Secretaria de Vigilância em Saúde. Boletim Epidemiológico. 48 (36).
Brasil. Ministério da Saúde. (2006). Diretrizes para controle da sífilis congênita: manual de bolso, Secretaria de Vigilância em Saúde, Manuais Programa Nacional de DST/Aids. https://bvsms.saude.gov.br/bvs/publicacoes/manual_sifilis_bolso.pdf.
Cooper, J. M.; & Michelowb, I. C.; & Wozniaka, S. P.; & Sanchez, P. J. (2016) In time: the persistence of congenital syphilis in Brazil. Revista Paulista de Pediatria. Rev. paul. pediatr. 34(3). São Paulo July/Sept. http://dx.doi.org/10.1016/j.rppede.2016.06.004.
Domingues, R. M. S. M., & Leal, M.C. (2016). Incidence of congenital syphilis and factors associated with vertical transmission: data from the Birth in Brazil study. Cad.Saúde Pública, 32 (6), e00082415. https://doi.org/10.1590/0102-311X00082415.
Domingues, R. M. S. M., & Saracen, V., & Hartz, Z. M. A., & Leal, M. C. (2013). Congenital syphilis: a sentinel event in antenatal care quality. Rev. Saúde Pública, 47 (1), 147-157. https://www.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102013000100019.
Hawkes, S; & Matin, N.; & Broutet, N.; & Low, N. Effectiveness of interventions to improve screening for syphilis in pregnancy: a systematic review and meta-analysis. (2011) Lancet Infect Dis 11(9):684-91. http://dx.doi. org/10.1016/S1473-099(11)70104-9.
Lazarini, F. M.; & Barbosa, D.A. Intervenção educacional na Atenção Básica para prevenção da sífilis congênita. (2017). Revista Latino-Americana De Enfermagem, 25, e2845-. https://doi.org/10.1590/1518-8345.1612.2845.
Magalhães, D. M. S.; & Kawaguchi, I. A. L.; & Dias, A.; & Calderon, I. M. (2011) Siphylis in pregnancy and their influence on fetal and maternal morbidity. Com. Ciências Saúde. S43-S54, 2011.
Mazin, R., & Zacarías, F., & Valderrama, J. (2004). Maternal syphilis and congenital syphilis in Latin America: big problem, simple solution. Rev Panam Salud Publica, 16 (3), 211-217. https://www.scielosp.org/article/rpsp/2004.v16n3/211-217/.
Mullick, S., & Broutet, N., & Htun, T., & Temmerman, M., Ndowa. (2004). Bulletin of the World Health Organization, 82 (6), 431-432. https://www.scielosp.org/article/bwho/2004.v82n6/431-432/.
Oliveira, V. S.; & Rodrigues, R. L.; & Chaves, V. B.; & Santos, T. S.; & De Assis, F. M.; & Ternes, Y. M. F.; & Aquino, E. C. (2020) Aglomerados de alto risco e tendência temporal da sífilis congênita no Brasil. Rev Panam Salud Publica.; 44:e75. https://doi.org/10.26633/RPSP.2020.75.
Paiva, M. R. R., & Silva, R. C. S., & Olivindo, D. D. F. (2020). Congenital syphilis in Brazil: a reality to be faced, 9 (10), e7990109258. http://dx.doi.org/10.33448/rsd-v9i10.9258.
Peeling, R. W., & Ye, H. (2004). Diagnostic tools for preventing and managing maternal and congenital syphilis: an overview. Bulletin of the World Health Organization, 82(6), 439–446.
Pereira, A. S. et al. (2018). Metodologia da pesquisa científica. UFSM. Htps://repositório.ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Ciencia.pdf?sequence
Ribeiro, R. S., & Segura, G. S., & Ferreira A. C. M., & Sasaki, N. S. G. M. S., & Santos, M. L. S. G., & Vendramini, S. H. F. (2020). Epidemiology of gestational and congenital syphilis: integrative literature review, 9 (4) e178942470. https://rsdjournal.org/index.php/rsd/article/view/2470/2727. http://dx.doi.org/10.33448/rsd-v9i4.2470.
Rodrigues, C. S., & Guimarães, M. D. C., & César, C. C. (2008). Missed opportunities for congenital syphilis and HIV perinatal transmission prevention. Revista de Saúde Pública, 42(5), 851-858. https://dx.doi.org/10.1590/S0034-89102008000500010.
Saraceni, V.; & Pereira, G. F. M.; & Silveira, M. F.; & Araujo, M. A. L.; & Miranda, A. E. (2017) Vigilância epidemiológica da transmissão vertical da sífilis: dados de seis unidades federativas no Brasil. Rev Panam Salud Publica. 41:e44. 10.26633/RPSP.2017.44.
Secretaria de Estadual de São Paulo (2009). Programa Estadual DST/Aids de São Paulo. 2009, http://www3.crt.saude.sp.gov.br/iec/pe_dst_aids_sp_portugues.pdf.
Siegel, S., & Castellan, Jr, N. J. (2006). Estatística não paramétrica para ciências do comportamento. Segunda edição. Artmed.
Starling S. P. (1994). Syphilis in infants and young children. Pediatric annals, 23(7), 334–340. https://doi.org/10.3928/0090-4481-19940701-06.
Valderrama, J., & Urquia Bautista, A., & Orlich, G., & Siri, R. S., & Luz Osimani, M., & Abreu, H., & Messano, L. C., & Pedreira, W., & Braselli, A., & Fonseca, M. G.M., & Matida, L. H., & Saraceni, V., & Pinto, V., & de Oliveira, E. C., & Kamb, M. L., & Almanzar, A., & Hernandez, Y. (2005). Maternal and congenital syphilis: case definitions. Epidemiological bulletin, 26(1), 12–15.
Zuzarte, J. S., & Santos, I. M. M., & Silva, A. S., & Silva, L. C. O., & Santos, V. F., Rebello, P. D. (2020). Profile of pregnant women with syphilis in public maternity, 9 (11), e46091110106. http://dx.doi.org/10.33448/rsd-v9i11.10106.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 Karina Bonilha Roque ; Bruna de Paula Alves; Beatriz Félix da Silva; Neil Ferreira Novo; Yara Juliano ; Jefferson Carlos de Oliveira; Jane de Eston Armond

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.