Evaluación de la duración y el riesgo de sangrado entre diferentes estrategias antiplaquetarias duales administradas después de una intervención coronaria percutánea: una revisión de alcance

Autores/as

DOI:

https://doi.org/10.33448/rsd-v12i8.42867

Palabras clave:

Terapia antiplaquetaria doble; Inhibidores de agregación plaquetaria; Hemorragia.

Resumen

Los pacientes con Síndrome Coronario Agudo (SCA) requieren la implantación de stents liberadores de fármacos tras una intervención coronaria percutánea (ICP), asociado a la administración de terapia antiplaquetaria dual (TDAP) para reducir el riesgo trombótico. Considerando la evaluación entre la protección isquémica y la posibilidad de eventos hemorrágicos, se han utilizado nuevas estrategias TDAP, que permiten la prevención de posibles resultados perjudiciales. El presente estudio tiene como objetivo evaluar la duración y el riesgo de sangrado entre diferentes estrategias de TDAP administradas después de la ICP. Para esta revisión de alcance, realizada a través de las plataformas PubMed y ScienceDirect, entre los años 2020 y 2023, los descriptores elegidos fueron: ''Inhibidores de la agregación plaquetaria'', ''Intervención coronaria percutánea'' y ''Hemorragia''. Los criterios de inclusión consistieron en (1) evaluación de la duración y el riesgo de sangrado en diferentes estrategias de TDAP (2) análisis entre diferentes tipos de agentes antiplaquetarios (3) estudios que abordaron el seguimiento y el manejo clínico (4) artículos en inglés y portugués. Los criterios de exclusión consistieron en inadecuación al tema, relatos de casos, editoriales, reseñas simples, estudios en animales, además de textos fuera del límite de tiempo. Los regímenes de TDAP prolongados y de acción prolongada mostraron una mayor protección isquémica y un mayor riesgo de hemorragia. Los regímenes de corta o muy corta duración se asociaron con tasas reducidas de hemorragia mayor, siendo beneficiosos para los pacientes de edad avanzada o con trombocitopenia. El manejo de los casos con alto riesgo trombótico y hemorrágico, así como el uso de puntajes predictivos siguen siendo temas controvertidos por dilucidar a través de nuevos estudios.

Citas

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17/08/2023

Cómo citar

SANTOS, T. L. .; PARREIRA, W. da S. P. .; FRACARO, A. C.; CAMPOS, D. R. .; PAVONI, B. de C. .; BEZERRA NETO, P. D. .; SADY, L. M. da R. .; PINHO, L. A. de .; PEREIRA, L. F. B. . Evaluación de la duración y el riesgo de sangrado entre diferentes estrategias antiplaquetarias duales administradas después de una intervención coronaria percutánea: una revisión de alcance. Research, Society and Development, [S. l.], v. 12, n. 8, p. e7112842867, 2023. DOI: 10.33448/rsd-v12i8.42867. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/42867. Acesso em: 17 jul. 2024.

Número

Vol. 12 Núm. 8

Sección

Ciencias de la salud

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Derechos de autor 2023 Trinnye Luizze Santos; Walquiria da Silva Pedra Parreira; Augusto Cesar Fracaro; Davi Resende Campos; Bianca de Campos Pavoni; Pedro Dias Bezerra Neto; Louise Mota da Rocha Sady; Lênio Airam de Pinho; Lucas França Belfort Pereira

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