Human papillomavirus and coinfections with Chlamydia trachomatis and Gardnerella vaginalis in women treated in a private laboratory in the city of Aracaju- Sergipe, Brazil
DOI:
https://doi.org/10.33448/rsd-v13i1.44631Keywords:
Chlamydia infections; Human papillomavirus; Bacterial vaginosis.Abstract
The human papillomavirus (HPV) is associated with the development of cervical cancer, in which different factors may be associated with the persistence and progression of precancerous lesions, one of these factors being co-infections between HPV, Chlamydia trachomatis (CT) and Gardnerella vaginalis (GV). Thus, the objective of the work is to verify the incidence of HPV and CT and GV co-infections in women treated in a private laboratory in Aracaju, located in the state of Sergipe. The study is descriptive, cross-sectional and retrospective, analyzing the results of high-risk HPV genotyping tests, tomographic research and cytopathological examination, carried out between January and October 2022. During the study period, 1,312 women underwent vaginal secretion collection, with other high oncogenic risk HPV genotypes other than 16 and/or 18 being detected in 80.65% (296/367) of cases, followed by HPV-16 with 8.71% (32/367) and HPV- 18 with 3.82% (14 /367). Among patients infected with HPV, there were 30.7% (113/367) cases of co-infections, 14.16% (16/113) by CT and 81.42% (92/113) by GV, in addition to triple findings. infection, in 4.42% (5/113) of cases. Thus, it was observed that there was a higher incidence of HPV genotypes different from 16 and/or 18, in addition to cases of double and triple co-infections being found in women treated in the laboratory.
References
Almeida, F. G., et al. (2014) Molecular epidemiology of the human papillomavirus infection in self‐collected samples from young women. Journal of medical virology, 86(2), 266-271.
Anjos, K. M., et al. (2022). Prevalência de Gardnerella vaginalis em exames de colpocitologia no Município de Colméia–Tocantins, Brasil. Research, Society and Development, 11 (15), e260111537087-e260111537087, 2022
Akakpo, P. K., et al. (2023). High-risk human papillomavirus genotype distribution among women living with HIV, implication for cervical cancer prevention in a resource limited setting. Infectious Agents and Cancer, 18(1), 1-13.
Araújo, L. N. C. C., et al. (2021) Impactos biopsicossociais do diagnóstico positivo de HPV nos portadores. Revista Eletrônica Acervo Saúde, 13(5), e7358-e7358.
Barcelos, M. R. B., et al. (2008). Infecções genitais em mulheres atendidas em Unidade Básica de Saúde: prevalência e fatores de risco. Revista Brasileira de Ginecologia e Obstetrícia, 30, 349-354.
Ferrera, L., et al. (2023). The association of Chlamydia trachomatis and human papillomavirus co-infection with abnormal cervical cytology among women in south of Morocco. Microbial Pathogenesis, 175, 105971.
Giraldo, P. C., et al. (2005). Influência da frequência de coitos vaginais e da prática de duchas higiênicas sobre o equilíbrio da microbiota vaginal. Rev. Bras. Ginecol. Obstet, 27, 257-62.
Jahnke, R., et al. (2022). Chlamydia trachomatis Cell-to-Cell Spread through Tunneling Nanotubes. Microbiology Spectrum, 10(6), e02817-22.
Kyrgiou, M. & Moscicki, A. B. (2022). Vaginal microbiome and cervical cancer. In: Seminars in Cancer Biology. Academic Press, 86, 189-198.
Lugo, L. Z. A., et al. (2018). Human papillomavirus and coinfections with Chlamydia trachomatis, Gardnerella vaginalis, and Trichomonas vaginalis in self-collected samples from female sex workers in the Central-Western region of Brazil. Jornal Brasileiro de Patologia e Medicina Laboratorial, 54, 46-51.
Madeleine, M. M., et al. (2007). Risk of cervical cancer associated with Chlamydia trachomatis antibodies by histology, HPV type and HPV cofactors. International journal of cancer, 120 (3), 650-655.
Moura, L. D. L., Codeço, C. T. & Luz, P. M. (2020). Cobertura da vacina papilomavírus humano (HPV) no Brasil: heterogeneidade espacial e entre coortes etárias. Revista brasileira de epidemiologia, 24.
Mosmann, J. P., et al. (2021) Human papillomavirus and Chlamydia trachomatis in oral and genital mucosa of women with normal and abnormal cervical cytology. BMC Infectious Diseases, 21(1), 1-8.
Oliveira, E. H. & Soares, L. F. (2007). Prevalência de vaginites infecciosas através da citologia clínica: um estudo no Laboratório Central de Saúde Pública do Piauí. RBAC. 39(33).
Romero-Morelos, P., et al. (2019). Bacterias relacionadas con vaginosis bacteriana y su asociación a la infección por virus del papiloma humano. Medicina Clínica, 152(1), 1-5.
Soohoo, M., et al. (2013). Cervical HPV infection in female sex workers: a global perspective. The open AIDS journal, 7(58).
Sun, J. X., et al. (2023). The association between human papillomavirus and bladder cancer: Evidence from meta‐analysis and two‐sample mendelian randomization. Journal of Medical Virology, 95(1).
Tognon, M., et al. (2020). Investigation on spontaneous abortion and human papillomavirus infection. Vaccines, 8(3), 473.
Viñas-Sifontes, L. N., Chávez-Roque, M. & Calderón-Cruz, M. (2020). Papilomavírus humano em adolescentes e jovens com menos de 25 anos. Revista Arquivo Médico Camagüey, 24.
Wierzbicka, M., et al. (2023) Transmission and clearance of human papillomavirus infection in the oral cavity and its role in oropharyngeal carcinoma–A review. Reviews in medical virology, 33(1), e2337.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Rafaela Windy Farias dos Santos; Odara Regina Menezes de Santana; Danielly Silva de Santana; Sinthia Regina dos Santos Lóz; Juçara Santos de Melo; Pâmela Silva Santos; Renata Cibelle Farias dos Santos
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
