From farm to industry: An overview of tomatoes, lycopene's health benefits, and the sustainable valorization of by-products

Authors

DOI:

https://doi.org/10.33448/rsd-v14i2.48276

Keywords:

Tomato; Lycopene; Bioactive compounds; Sustainable extraction; Industrial by-products.

Abstract

This study aims to review the current knowledge on tomatoes and carotenoids, particularly lycopene, highlighting their health benefits and the sustainable utilization of by-products from the tomato processing industry. Belonging to the Solanaceae family, the tomato (Solanum lycopersicum L.) is one of the most consumed vegetables worldwide, appreciated both fresh and in processed products. The tomato industry generates a large volume of waste, and improper management can cause environmental issues, besides leading to the loss of valuable bioactive compounds such as lycopene. Lycopene possesses high antioxidant capacity, and its consumption has been associated with a reduced risk of certain types of cancer and cardiovascular diseases. Innovative and sustainable extraction methods, including the use of green solvents and technologies such as supercritical fluid, ultrasound-assisted, and other emerging techniques, are being explored to optimize the valorization of these by-products, contributing to the circular economy and sustainability. Further research is needed to overcome current challenges and promote solutions for reducing environmental impacts, achieving efficient and sustainable extraction, lowering costs, and improving the scalability of extraction technologies to obtain high-value products for various applications.

References

Ashim, L. (2023). Informe de investigación, participación y tamaño del mercado de licopeno. Kings Research.

https://www.kingsresearch.com/es/lycopene-market-1036

Bergougnoux, V. (2014). The history of tomato: From domestication to biopharming. Biotechnology Advances, 32(1), 170–189. https://doi.org/10.1016/j.biotechadv.2013.11.003

Branthôme, F.-X. (2022). Consumption: 2021 in the wake of 2020. Tomato News. https://www.tomatonews.com/en/consumption-2021-in-the-wake-of-2020_2_1618.html

Caseiro, M., Ascenso, A., Costa, A., Creagh-Flynn, J., Johnson, M., & Simões, S. (2020). Lycopene in human health. LWT, 127, 109323. https://doi.org/10.1016/j.lwt.2020.109323

Clinton, S. K. (1998). Lycopene: Chemistry, Biology, and Implications for Human Health and Disease. Nutrition Reviews, 56(2), 35–51. https://doi.org/10.1111/j.1753-4887.1998.tb01691.x

FAO. (2021). World Food and Agriculture – Statistical Yearbook 2021. FAO. https://doi.org/10.4060/cb4477en

FAO - Faostat. (2023). [FAOstatistics]. Food and Agriculture Organiation of the United Nations. https://www.fao.org/faostat/en/#rankings/countries_by_commodity

FAOSTAT. (2023). https://www.fao.org/faostat/en/#data/QCL

Filgueira, F. A. R. (2008). Novo Manual de Olericultura. (3a ed.). Editora UFV.

Garcia-Garcia, G., Woolley, E., Rahimifard, S., Colwill, J., White, R., & Needham, L. (2017). A Methodology for Sustainable Management of Food Waste. Waste and Biomass Valorization, 8(6), 2209–2227. https://doi.org/10.1007/s12649-016-9720-0

Gómez-Romero, M., Arráez-Román, D., Segura-Carretero, A., & Fernández-Gutiérrez, A. (2007). Analytical determination of antioxidants in tomato: Typical components of the Mediterranean diet. Journal of Separation Science, 30(4), 452–461. https://doi.org/10.1002/jssc.200600400

Górecka, D., Wawrzyniak, A., Jȩdrusek-Golińska, A., Dziedzic, K., Hamułka, J., Kowalczewski, P., & Walkowiak, J. (2020). Lycopene in tomatoes and tomato products. Open Chemistry, 18(1), 752–756. Scopus. https://doi.org/10.1515/chem-2020-0050

Guil-Guerrero, J., Ramos, L., Moreno, C., Zuniga-Paredes, J., Carlosama-Yepez, M., & Ruales, P. (2016). Plant Foods By-Products as Sources of Health-Promoting Agents for Animal Production: A Review Focusing on the Tropics. Agronomy Journal, 108(5), 1759–1774. https://doi.org/10.2134/agronj2015.0555

IBGE. (2021). Produção de Tomate no Brasil. https://www.ibge.gov.br/explica/producao-agropecuaria/tomate/br

Khan, U. M., Sevindik, M., Zarrabi, A., Nami, M., Ozdemir, B., Kaplan, D. N., Selamoglu, Z., Hasan, M., Kumar, M., Alshehri, M. M., & Sharifi-Rad, J. (2021). Lycopene: Food Sources, Biological Activities, and Human Health Benefits. Oxidative Medicine and Cellular Longevity, 2021, 1–10. https://doi.org/10.1155/2021/2713511

Khoo, H.-E., Prasad, K. N., Kong, K.-W., Jiang, Y., & Ismail, A. (2011). Carotenoids and Their Isomers: Color Pigments in Fruits and Vegetables. Molecules, 16(2), 1710–1738. https://doi.org/10.3390/molecules16021710

Knoblich, M., Anderson, B., & Latshaw, D. (2005). Analyses of tomato peel and seed byproducts and their use as a source of carotenoids. Journal of the Science of Food and Agriculture, 85(7), 1166–1170. Scopus. https://doi.org/10.1002/jsfa.2091

Kong, K.-W., Khoo, H.-E., Prasad, K. N., Ismail, A., Tan, C.-P., & Rajab, N. F. (2010). Revealing the Power of the Natural Red Pigment Lycopene. Molecules, 15(2), Artigo 2. https://doi.org/10.3390/molecules15020959

Lu, S., Chen, S., Li, H., Paengkoum, S., Taethaisong, N., Meethip, W., Surakhunthod, J., Sinpru, B., Sroichak, T., Archa, P., Thongpea, S., & Paengkoum, P. (2022). Sustainable Valorization of Tomato Pomace (Lycopersicon esculentum) in Animal Nutrition: A Review. Animals, 12(23). https://doi.org/10.3390/ani12233294

Lu, Z., Wang, J., Gao, R., Ye, F., & Zhao, G. (2019). Sustainable valorisation of tomato pomace: A comprehensive review. Trends In Food Science & Technology, 86, 172–187. https://doi.org/10.1016/j.tifs.2019.02.020

Madia, V., De Vita, D., Ialongo, D., Tudino, V., De Leo, A., Scipione, L., Roberto, S., Costi, R., & Messore, A. (2021). Recent Advances in Recovery of Lycopene from Tomato Waste: A Potent Antioxidant with Endless Benefits. Molecules, 26(15). https://doi.org/10.3390/molecules26154495

Melo, P. C. T. de, & Vilela, N. J. (2005). Desafios e perspectivas para a cadeia brasileira do tomate para processamento industrial. Horticultura Brasileira, 23, 154–157. https://doi.org/10.1590/S0102-05362005000100032

Misawa, N. (2010). Carotenoids. Em Comprehensive Natural Products II - Chemistry and Biology (1o ed, p. 733–753). Hung-Wen (Ben) Liu Lew Mander. https://doi.org/10.1016/B978-008045382-8.00009-5

Neitzke, R. S., & Büttow, M. V. (2008). Origem e Evolução das Plantas Cultivadas—Tomate. Em Origem e Evolução das Plantas Cultivadas (1a, p. 803–818). Rosa Lía Barbieri, Elisabeth Regina Tempel Stumpf. https://www.bibliotecaagptea.org.br/agricultura/biologia/livros/ORIGEM%20E%20EVOLUCAO%20DE%20PLANTAS%20CULTIVADAS%20-%20 EMBRAPA.pdf

Nisar, N., Li, L., Lu, S., Khin, N. C., & Pogson, B. J. (2015). Carotenoid Metabolism in Plants. Molecular Plant, 8(1), 68–82. https://doi.org/10.1016/j.molp.2014.12.007

Peralta, I. E., & Spooner, D. M. (2005). Morphological characterization and relationships of wild tomatoes (Solanum L. Section Lycopersicon [Mill.] Wettst. Subsection Lycopersicon). https://ri.conicet.gov.ar/handle/11336/107948

Rawat, A., Upadhyay, M., & Singh, O. (2024). Exploring the pharmacological potential and traditional use of Solanum lycopersicum L. (Tomato): A review. Journal of Pharmacognosy and Phytochemistry, 13(2), 768–771. https://doi.org/10.22271/phyto.2024.v13.i2f.14920

Saini, R. K., Rengasamy, K. R. R., Mahomoodally, F. M., & Keum, Y.-S. (2020). Protective effects of lycopene in cancer, cardiovascular, and neurodegenerative diseases: An update on epidemiological and mechanistic perspectives. Pharmacological Research, 155, 104730. https://doi.org/10.1016/j.phrs.2020.104730

Salehi, B., Sharifi-Rad, R., Sharopov, F., Namiesnik, J., Roointan, A., Kamle, M., Kumar, P., Martins, N., & Sharifi-Rad, J. (2019). Beneficial effects and potential risks of tomato consumption for human health: An overview. Nutrition, 62, 201–208. https://doi.org/10.1016/j.nut.2019.01.012

Shin, J., Song, M.-H., Oh, J.-W., Keum, Y.-S., & Saini, R. K. (2020). Pro-oxidant Actions of Carotenoids in Triggering Apoptosis of Cancer Cells: A Review of Emerging Evidence. Antioxidants, 9(6), 532. https://doi.org/10.3390/antiox9060532

Silva, Y. P. A., Ferreira, T. A. P. C., Celli, G. B., & Brooks, M. S. (2019). Optimization of Lycopene Extraction from Tomato Processing Waste Using an Eco-Friendly Ethyl Lactate–Ethyl Acetate Solvent: A Green Valorization Approach. Waste and Biomass Valorization, 10(10), 2851–2861. https://doi.org/10.1007/s12649-018-0317-7

Strati, I. F., & Oreopoulou, V. (2014). Recovery of carotenoids from tomato processing by-products – a review. Food Research International, 65, 311–321. https://doi.org/10.1016/j.foodres.2014.09.032

Teixeira, F. M. V., Mendonça, J. L., & Alvarenga, M. A. R. (2022). Tratos Culturais—Tomate. Embrapa.

https://www.embrapa.br/hortalicas/tomate-de-mesa/tratos-cultuais

Tropicos.org. (2025). Tropicos.org. Missouri Botanical Garden. https://www.tropicos.org/name/Search?name=Solanum%20lycopersicon

Vieira, D. A. D. P., Caliari, M., Souza, E. R. B. D., & Soares Júnior, M. S. (2019). Mechanical resistance, biometric and physicochemical characteristics of tomato cultivars for industrial processing. Food Science and Technology, 39(suppl 2), 363–370. https://doi.org/10.1590/fst.32417

Viñas-Ospino, A., López-Malo, D., Esteve, M. J., Frígola, A., & Blesa, J. (2023). Green Solvents: Emerging Alternatives for Carotenoid Extraction from Fruit and Vegetable By-Products. Foods, 12(4), Artigo 4. https://doi.org/10.3390/foods12040863

World trade in Tomato Products. (2023). Tomato News. https://www.tomatonews.com/en/trade_46.html

WPTC - World Processing Tomato Council. (2023). WPTC. https://www.wptc.to/production/

Wu, S.-X., Li, J., Zhou, D.-D., Xiong, R.-G., Huang, S.-Y., Saimaiti, A., Shang, A., & Li, H.-B. (2022). Possible Effects and Mechanisms of Dietary Natural Products and Nutrients on Depression and Anxiety: A Narrative Review. Antioxidants, 11(11), 2132. https://doi.org/10.3390/antiox11112132

Zhao, Y., Bao, R.-K., Zhu, S.-Y., Talukder, M., Cui, J.-G., Zhang, H., Li, X.-N., & Li, J.-L. (2021). Lycopene prevents DEHP-induced hepatic oxidative stress damage by crosstalk between AHR–Nrf2 pathway. Environmental Pollution, 285, 117080. https://doi.org/10.1016/j.envpol.2021.117080

Published

23/02/2025

How to Cite

STECKELBERG, R. M. de B.; CONCEIÇÃO, E. C. da. From farm to industry: An overview of tomatoes, lycopene’s health benefits, and the sustainable valorization of by-products. Research, Society and Development, [S. l.], v. 14, n. 2, p. e10214248276, 2025. DOI: 10.33448/rsd-v14i2.48276. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/48276. Acesso em: 6 jun. 2025.

Issue

Section

Review Article