Main bacteria of hospital infection after neurosurgery: A narrative review

Authors

DOI:

https://doi.org/10.33448/rsd-v14i4.48637

Keywords:

Infectology; Pathophysiology; Neurosurgery.

Abstract

Post-neurosurgical procedure infections, resulting from direct contact with bacteria within the surgical center, directly affect the patient's good prognosis, leading to complications that can lead to admission to the intensive care unit (ICU). According to a survey of data from the World Health Organization (WHO), in Brazil alone, surgical site infections (SSI) are responsible for around 15% of all infections related to healthcare, increasing the average length of stay in the ICU by 60%. The Central Nervous System (CNS) controls the body's functions, guiding almost everything through signals in networks of neurons and releasing substances at the tips of cells. The nervous tissue feels everything from the outside and inside, reacting by sending rapid and constant nervous warnings. In summary, central nervous system infections continue to be a significant burden on healthcare systems around the world. However, advances made in understanding its pathophysiology in the last 20 years surpass anything that has been done before.

References

Boaventura, J. E.M. et al (2019). Infecções de sítio cirúrgico: incidência e perfil de resistência antimicrobiana em unidade de terapia intensiva. Rev. baiana enferm., 2019; 33, 2-6

Campos, L G, et al. (2021). Central nervous system infection: imaging findings suggestive of a fungus as the cause. Radiologia Brasileira; 54, 198-203.

Carvalho J V C, et al (2021) Bactérias multirresistentes e seus impactos na saúde pública: Uma responsabilidade social. Pesquisa, Sociedade e Desenvolvimento ,(S. L. ), 10(6),

Cordeiro, E W F et al. (2020) Validation of an analytical method by high-performance liquid chromatography and microbiological assay, biological safety and in silico toxicity for danofloxacin. Brazilian Journal of Pharmaceutical Sciences [online], v. 56

Costa, P. M. et al. (2015). Infection with multidrug-resistant gram-negative bacteria in a pediatric oncology intensive care unit: risk factors and outcomes.. Jornal de Pediatria; 9(5), 435-441.

Dobran, M, et al. (2017). Risk factors of surgical site infections in instrumented spine surgery. Surg Neurol Int; 8, 212-24.

Ferrari N, et al. (2024). Complicações em Neurocirurgia: Uma Análise Detalhada e Estratégias de Prevenção. Brazilian Journal of Implantology and Health Sciences. 6. 1389-1400. 10.36557/2674-8169.2024v6n2p1389-1400.

Figueiredo, E. G. (2012). Infecções em pós-craniotomias: revisão literária. Arq Bras Neurocir; 31(4), 219-23, 2012.

Gomes, F C A, et al. (2013). Glia: dos velhos conceitos às novas funções de hoje e as que ainda virão. Estudos Avançados; 27, 61-84.

Guimaraes, A B M.; et al (2022) Detecção de bactérias a partir de culturas através de antibiogramas na Terapia Intensiva Adulto de um hospital de referência do norte do Ceará. Pesquisa, Sociedade e Desenvolvimento , [S. l.], v. 13.

Ibanez, F. A. L., et al. (2011) A new classification of complications in neurosurgery. World Neurosurg; 75, 709-715.

Junior, N. C, et al. (2014) Governmental surveillance system of healthcare-associated infection in Brazil. Rev Esc Enferm USP. 2014; 48, 657-62.

Karhade, A V, et al. (2017) Neurosurgical infection rates and risk factors: a national surgical quality improvement program analysis of 132,000 patients, 2006–2014. World Neurosurg. 2017; 97, 205-12.

Kraemmer, K. & Dalmaso, A. (2023). Explorando o mundo das bactérias: uma abordagem prática durante o Estágio Supervisionado em Ciências Biológicas. Research, Society and Development. 12. e11512742534. 10.33448/rsd-v12i7.42534.

Marta, A et al (2019). Estudo epidemiológico das queratites infeciosas internadas num centro hospitalar terciário - revisão de 5 anos. Revista Brasileira de Oftalmologia, 78(6), 370-374.

Pereira A. S. etal. (2018). Metodologia da pesquisa científica.UFSM.

Ribeiro E, et al (2022). Infecções secundárias causadas por bactérias do grupo ESKAPE e impacto à saúde de pacientes com complicações da Covid-19 – uma revisão integrativa. Research, Society and Development. 11. e289111537997. 10.33448/rsd-v11i15.37997.

Rolston, J. D., et al. (2014) Frequency and predictors of complications in neurological surgery: national trends from 2006 to 2011. J Neurosurg. 2014;.120(3), 736-745.

Santos, A L et al. (2007) Staphylococcus aureus: visitando uma cepa de importância hospitalar. Jornal Brasileiro de Patologia e Medicina Laboratorial. 2007; 43(6), 413-423.

Siqueira, E.M.P. et al. (2017) Complicações pós-operatórias em neurocirurgia eletiva e não eletiva. Acta Paulista de Enfermagem; 30.(1): 101-108.

Published

16/04/2025

How to Cite

PACHECO, J. de A.; PRIVADO, R. J. T.; BATISTA, B. C.; SANTANA, H. de C. M.; ALVES JÚNIOR, M. M.; MAIA, P. D. K.; JUNQUEIRA, R. P.; SABOYA, M. S. de; SOUZA, D. A. R. de; VALADARES, G. P. Main bacteria of hospital infection after neurosurgery: A narrative review . Research, Society and Development, [S. l.], v. 14, n. 4, p. e4014448637, 2025. DOI: 10.33448/rsd-v14i4.48637. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/48637. Acesso em: 4 jun. 2025.

Issue

Section

Health Sciences