Clinical and epidemiological analysis of gastric and duodenal ulcer cases in Brazil between 2017 and 2024

Authors

DOI:

https://doi.org/10.33448/rsd-v14i5.48771

Keywords:

Epidemiology; Gastric ulcer; Duodenal ulcer.

Abstract

Introduction: Gastric and duodenal ulcers are prevalent conditions that affect the mucosa of the stomach and duodenum, respectively, and are associated with a significant impact on public health. Therefore, this article aims to provide a quantitative and temporal analysis of the epidemiological characteristics of gastric and duodenal ulcers from January 2017 to September 2024. Methodology: This is an epidemiological study carried out based on data from the health information department of the SUS (Unified Health System). The variables used were: hospital admissions, deaths, age group, color/race, sex, hospital expenses, and health macroregion.Methodology: This is an epidemiological study carried out based on data from the health information department of the SUS (Unified Health System). The variables used were: hospital admissions, deaths, age group, color/race, sex, hospital expenses and health macro-region. Results: 86,505 hospitalizations were due to ulcers and in the period analyzed the highest number of hospitalizations was in 2013. The Southeast region was the most reported regarding the number of hospitalizations and the one where most individuals died due to complications. The largest age group affected was between 60 and 69 years old. Males were the gender most affected by this pathology. Regarding ethnicity, more brown patients were hospitalized. In addition, the Southeast region had the highest average number of days of hospitalization. Conclusion: Understanding these trends is essential for formulating effective public health policies and for better allocation of resources for treating these diseases. In addition, epidemiological analysis can guide preventive actions, such as educational campaigns on the appropriate use of NSAIDs and the need to eradicate H. pylori.

References

Atay, A. et al. (2023). From dyspepsia to complicated peptic ulcer: New markers in diagnosis and prognosis. Eur Rev Med Pharmacol Sci. 27(4), 1352-9. doi: 10.26355/eurrev_202302_31370.

Bardhan, K. D. & Royston, C. (2008). Time, change and peptic ulcer disease in Rotherham, UK.Dig Liver Dis. 40(7), 540-6.

Bao, Y., Spiegelman, D., Li, R., Giovannucci, E., Fuchs, C. S. & Michaud, D. S. (2010). History of peptic ulcer disease and pancreatic cancer risk in men. Gastroenterology. 138(2), 541-9.

Chiorean, M. V., Locke, G. R. 3rd, Zinsmeister, A. R., Schleck, C. D., Melton, L.J. 3rd. (2002). Changing rates of Helicobacter pylori testing and treatment in patients with peptic ulcer disease. Am J Gastroenterol. 97(12), 3015-22.

Chisini, L. A. et al. (2021). Impact of the COVID-19 pandemic on prenatal, diabetes and medical appointments in the Brazilian National Health System. Revista Brasileira de Epidemiologia. 24, e210013.

Coelho, S. F. F., Pizetta, L. T., da Silveira, G. A., Frizon, G. J., Sampaio, A. L. S., de Souza, A. V., ... & de Almeida Melo, M. (2024). Úlcera gástrica e duodenal: uma análise atualizada do cenário da saúde digestiva no Brasil. Brazilian Journal of Implantology and Health Sciences. 6(8), 2264-74.

Denizar, J. G. M. et al. (2024). Doença ulcerosa péptica: epidemiologia, fisiopatologia, diagnóstico e tratamento. Revista Ibero-Americana de Humanidades, Ciências e Educação. 10(7), 3004–15.

Atay, A., Karahan, F., Gunes, O. & Gunay, S. (2023). From dyspepsia to complicated peptic ulcer: new markers in diagnosis and prognosis. European Review for Medical and Pharmacological Sciences, 27, 1352–9.

Graham, D. Y., Lidsky, M. D., Cox, A. M., Evans, D. J. Jr, Evans, D. G., Alpert, L., Klein, P. D., Sessoms, S. L., Michaletz, P. A. & Saeed, Z. A. (2020). Long-term nonsteroidal antiinflammatory drug use and Helicobacter pylori infection. Gastroenterology. 100(6), 1653-7.

Hawkey, C. J. et al. (2022). Helicobacter pylori eradication for primary prevention of peptic ulcer bleeding in older patients prescribed aspirin in primary care (HEAT): a randomised, double-blind, placebo-controlled trial. The Lancet. 400, 10363, 1597–606.

Laucirica, I., Garcia Iglesias, P., & Calvet, X. (2023). Úlcera péptica. Medicina Clínica. 161(6), 260–66.

Lisboa, M. G. et al. (2024). Úlcera péptica - uma revisão de literature. Brazilian Journal of Health Review, Curitiba. 7(2), 1-12.

Loeb, D. S., Talley, N. J., Ahlquist, D. A., Carpenter, H. A. & Zinsmeister, A. R. (2020). Long-term nonsteroidal anti-inflammatory drug use and gastroduodenal injury: the role of Helicobacter pylori. Gastroenterology. 102(6), 1899-905.

Narayanan, M., Reddy, K. M. & Marsicano, E. (2018). Peptic Ulcer Disease and Helicobacter pylori infection. Missouri medicine. 115(3), 219-24. https://pubmed.ncbi.nlm.nih.gov/30228726/.

Pedraza, D. F., et al. (2017). Internações das crianças brasileiras menores de cinco anos: revisão sistemática da literatura. Epidemiologia e Serviços de Saúde, 26(1), 169–82.

Pereira A. S. et al. (2018). Metodologia da pesquisa científica. [free e-book]. Editora UAB/NTE/UFSM.

Shitsuka et al. (2014). Matemática fundamental para a tecnologia. Editora Érica.

Tham, K. T., Peek, R. M. Jr, Atherton, J. C., Cover, T. L., Perez-Perez, G. I., Shyr, Y. & Blaser, M. J. (2001). Helicobacter pylori genotypes, host factors, and gastric mucosal histopathology in peptic ulcer disease. Hum Pathol. 32(3), 264-73.

Toassi, R. F. C. & Petry, P. C. (2021). Metodologia científica aplicada à área da Saúde. 2ed. Editora da UFRGS. Vieira, S. (2021). Introdução à bioestatística. Ed.GEN/Guanabara Koogan

Published

20/05/2025

How to Cite

ANJOS, R. P. dos; MOTA, L. R.; PAIXÃO, A. A. T. da; GURGEL, S. P. Clinical and epidemiological analysis of gastric and duodenal ulcer cases in Brazil between 2017 and 2024. Research, Society and Development, [S. l.], v. 14, n. 5, p. e7114548771, 2025. DOI: 10.33448/rsd-v14i5.48771. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/48771. Acesso em: 6 jun. 2025.

Issue

Section

Health Sciences