Total phenolics, toxicity and antimicrobial activity of the essential oil of the leaves of Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm

Authors

DOI:

https://doi.org/10.33448/rsd-v9i7.5253

Keywords:

Alpinia; Antibacterial; Toxicity.

Abstract

This study aimed to determine total phenolics, assess toxicity and antimicrobial activity of essential oil (EO) of Alpinia zerumbet leaves. The EO was extracted by hydrodistillation and the physicochemical parameters were determined according to the Brazilian Pharmacopoeia. The toxicity assay followed the lethality bioassay against the non-target organism Artemia salina Leach. The antimicrobial activity followed the methodology described by the Clinical and Laboratory Standards Institute using the Method of Disc Diffusion and Broth Dilution to determine the Minimum Inhibitory Concentration (MIC) for the action of EE against Escherichia coli, Staphylococcus aureus, Aspergillus sp. and Penicilium sp. OE yield was 0.71%. Lethal Concentration 50% (LC50) for the action of EO against Artemia salina L. 280.40 mg/L, being considered nontoxic. Through the antimicrobial assays, the OE presented bactericidal activity against the bacteria E. coli and S. aureus,and fungicide activity against the fungi Aspergillus sp. and Penicillium sp. It was concluded that the EO has a good antimicrobial potential, and its application is appreciated by its classification as nontoxic OE..

Author Biographies

Matheus dos Santos Ribeiro, Universidade Federal do Maranhão, Laboratório de Pesquisa e Aplicação de Óleos Essenciais (LOEPAV/UFMA)

Bacharelado em Química pela UFMA

Gustavo Oliveira Everton, Universidade Federal do Maranhão

Mestrado em Saúde e Ambiente (UFMA), Universidade Federal do Maranhão, Laboratório de Pesquisa e Aplicação de Óleos Essenciais (LOEPAV / UFMA)

Paulo Victor Serra Rosa, Universidade Federal do Maranhão

Bacharelado em Biomedicina pela Uninassau

Erick Rickman Nascimento Pimenta, Universidade CEUMA

Bacharelado em Biomedicina pela CEUMA

Ari Pereira de Araújo Neto, Faculdade Maurício de Nassau

Mestre em Biotecnologia

Andressa Almeida Santana Dias, Faculdade Maurício de Nassau

Doutora em Biotecnologia

Ana Patrícia Matos Pereira, Universidade Federal do Maranhão

Bacharelada em Biomedicina pela Estácio

Dorileia Pereira do Nascimento, Faculdade Maurício de Nassau

Bacharelada em Biomedicina pela Uninassau

Ana Maria Almeida Silva Carvalho, Universidade Federal do Maranhão

Mestranda em Saúde do Adulto

Leila da Silva Silveira, Universidade Federal do Maranhão

Especialista em hematologia pela Universidade Federal de Goiás

Irlane Thais Pereira de Sousa, Faculdade Maurício de Nassau

Bacharelada em Biomedicina pela Uninassau

Victor Elias Mouchrek Filho, Universidade Federal do Maranhão

Doutorado em Química (USP), Universidade Federal do Maranhão

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Published

16/06/2020

How to Cite

RIBEIRO, M. dos S.; EVERTON, G. O.; SERRA ROSA, P. V.; PIMENTA, E. R. N.; ARAÚJO NETO, A. P. de; DIAS, A. A. S.; MATOS PEREIRA, A. P.; NASCIMENTO, D. P. do; CARVALHO, A. M. A. S.; SILVEIRA, L. da S.; SOUSA, I. T. P. de; MOUCHREK FILHO, V. E. Total phenolics, toxicity and antimicrobial activity of the essential oil of the leaves of Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm. Research, Society and Development, [S. l.], v. 9, n. 7, p. e953975253, 2020. DOI: 10.33448/rsd-v9i7.5253. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/5253. Acesso em: 22 nov. 2024.

Issue

Vol. 9 No. 7

Section

Health Sciences

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