Comparative analysis of neonatal jaundice mortality in Brazil, Northeast and Piauí: epidemiological series from 2010 to 2019
DOI:
https://doi.org/10.33448/rsd-v9i8.6423Keywords:
Hyperbilirubinemia; Neonatal jaundice; Kernicterus; Risk factors; Mortality.Abstract
Objective: to assess neonatal jaundice mortality in Brazil, Northeast and Piauí. Methodology: this is a retrospective epidemiological study, with a quantitative and descriptive design. Secondary data from the Mortality Monitoring Panel ICD-10 of the Ministry of Health of Brazil were used. The study included the series of deaths of children under 1 year of age due to neonatal jaundice and kernicterus, between the years 2010 and 2019, in Brazil, in the Northeast Region and in the State of Piauí. The Microsoft Office Excel 2019 program was used for simple descriptive analysis. Results: in the last 10 years, 1,008 deaths from neonatal jaundice occurred in Brazil. It was observed that mortality was more prevalent in males and in brown color/race. The specific causes of jaundice with higher mortality in Brazil and the Northeast were infection, premature birth and isoimmunization, respectively. In Piauí, the main cause was isoimmunization, followed by infection and premature birth. Conclusion: mortality from neonatal jaundice showed a downward trend in Brazil and the Northeast, while in Piauí it showed a small and stable annual average of cases. The comparison of the epidemiological situation of mortality due to jaundice between Brazil, the Northeast Region and the State of Piauí provides subsidies for the implementation of adequate prevention and control actions.
References
Bhutani, V. K., Wong, R. J., & Stevenson, D. K. (2016). Hyperbilirubinemia in Preterm Neonates. Clinics in Perinatology, 43(2), 215-232. doi: 10.1016/j.clp.2016.01.001
Brasil (2014). Ministério da Saúde. Secretaria de atenção à saúde. Departamento de ações programáticas e estratégicas. Atenção à saúde do recém-nascido: guia para os profissionais de saúde (2 ed.). Brasília: Ministério da Saúde. Recuperado em 25 de maio, 2020, de http://bvsms.saude.gov.br/bvs/publicacoes/atencao_saude_recem_nascido_v2.pdf
Brasil (2020). Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de
Análise de Saúde e Vigilância de Doenças Não Transmissíveis. Painel de Monitoramento da Mortalidade CID-10. Brasília. Recuperado em 10 de maio, 2020, de http://svs.aids.gov.br/dantps/centrais-de-conteudos/paineis-de-monitoramento/mortalidade/cid10/
Brits, H., Adendorff, J., Huisamen, D., Beukes, D., Botha, K., Herbst, H., & Joubert, G. (2018). The prevalence of neonatal jaundice and risk factors in healthy term neonates at National District Hospital in Bloemfontein. African journal of primary healthy care and family medicine, 10(1), 1-6. doi: https://doi.org/10.4102/phcfm.v10i1.1582
Cherepnalkovski, A. P., Krzelj, V., Zafirovska-Ivanovska, B., Gruev, T., Markic, J., Aluloska, N., ... & Piperkovska, K. (2015). Evaluation of Neonatal Hemolytic Jaundice: Clinical and Laboratory Parameters. Open Access Macedonian Journal of Medical Sciences, 3(4), 694-698. doi: http://dx.doi.org/10.3889/oamjms.2015.129
Chiou, F. K., Ong, C., Phua, K. B., Chedid, F., & Kader, A. (2017). Conjugated hyperbilirubinemia presenting in first fourteen days in term neonates. World journal of hepatology, 9(26), 1108-1114. Recuperado em 20 de maio, 2020, de https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612842/
Farouk, Z. L., Muhammed, A., Gambo, S., Mukhtar-Yola, M., Abdullahi, U., & Slusher, T. M. (2018). Folow-up of children with kernicterus in kano, nigeria. Journal of tropical pediatrics, 64(3), 176-182. doi:10.1093/tropej/fmx041
Filgueiras, S., Netto, A. L. O., Pereira, F. F., Alvarenga, L. V., Quaresma, M. S. R., & Gonçalves, R. V. (2017). Atenção à evolução da icterícia fisiológica para prevenção de kernicterus. Revista Interdisciplinar Ciências Médicas, 1(2), 36-45. Recuperado em 05 de maio, 2020, de http://revista.fcmmg.br/ojs/index.php/ricm/article/view/22/24
Gonzáles, A. L. G., Benavides, S. R. C., Jiménez, A. A. D., & Burbano, M. B. M. (2017). Factores predisponentes para ictericia neonatal em los pacientes egresados de la UCI neonatal, Hospital Infantil los Ángeles de Pasto. Universidad y Salud, 19(3), 352-358. doi: 10.22267/rus.171903.97
Gomes, I. C. N., Camargo, Y. S., Maciel, E. P., & Borges, R. C. (2017). Icterícia neonatal: uma revisão sobre as complicações e tratamento em recém-nascidos pré-termo. Simpósio de Trabalhos de Conclusão de Curso/Seminário de Iniciação Cientifica, 12, 465-469. Recuperado em 15 de maio, 2020, de http://nippromove.hospedagemdesites.ws/anais_simposio/arquivos_up/documentos/artigos/4c3f0f2f74276104d0f7c9b39cb42948.pdf
Lee, B. K., Le Ray, I., Sun, J. Y., Wikman, A., Reilly, M., & Johansson, S. (2016). Haemolytic and nonhaemolytic neonatal jaundice have diferente risk factor profiles. Acta Paediatrica, 105(12), 1444-1450. doi: 10.1111/apa.13470
Marostica, P. J. C., Villetti, M. C., Ferrelli, R. S., & Barros, E. (2018). Pediatria: consulta rápida (2 ed.). Porto Alegre: Artmed.
Mitra, S., & Rennie, J. (2017). Neonatal jaundice: aetiology, diagnosis and treatment. British Journal of Hospital Medicine, 78(12), 699-704. doi: 10.12968/hmed.2017.78.12.699
Mojtahedi, S. Y., Izadi, A., Seirafi, G., Khedmat, L., & Tavakolizadeh, R. (2018). Risk Factors Associated with Neonatal Jaundice: a Cross-Sectional Study from Iran. Open Access Macedonian Journal of Medical Sciences, 6(8), 1387-1393. doi: 10.3889/oamjms.2018.319
Olusanya, B. O., Osibanjo, F. B., & Slusher, T. M. (2018). Risk factors for severe neonatal hyperbilirubinemia in low and middle-income countries: a systematic review and meta-analysis. PloS one, 10(2). Recuperado em 07 de maio, 2020, de https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326461/.
Olusanya, B. O., Kaplan, M., & Hansen, T. W. R. (2018). Neonatal hyperbilirubinaemia: a global perpective. The Lancet Child and Adolescent Health, 2(8), 610-620. doi: 10.1016/S2352-4642(18)30139-1
Olusanya, B. O., Teeple, S., & Kassebaum, N. J. (2018). The contribution of neonatal jaundice to global child mortality: findings from the GBD 2016 study. Pediatrics, 141(2), e20171471, Recuperado em 15 de maio, 2020, de https://pediatrics.aappublications.org/content/141/2/e20171471
Rangel, J. A. R., Torres, P. E., & Nava, G. F. (2017). Etiología de ictericia neonatal em niños ingressados para tratamiento con fototerapia. Revista Mexicana de Pediatría, 84(3), 88-91. Recuperado em 15 de maio, 2020, de https://www.medigraphic.com/pdfs/pediat/sp-2017/sp173b.pdf
Rouquayrol, M. Z., & Silva, M. G. C. (2018). Epidemiologia & saúde (8 ed.) Rio de Janeiro: Medbook.
Wusthoff, C. J., & Loe, I. M. (2015). Impact of bilirubin-induced neurologic dysfunction on neurodevelopmental outcomes. Seminars in Fetal and Neonatal Medicine, 20(1), 52-57. doi: https://doi.org/10.1016/j.siny.2014.12.003.
YU, T. C., Nguyen, C., Ruiz, N., Zhou, S., Zhang, X., Böing, E. A., & Tan, H. (2019). Prevalence and burden of illness of treated hemolytic neonatal hyperbilirubinemia in a privately insured population in the United States. BMC Pediatrics, 19(1), 53. doi: https://doi.org/10.1186/s12887-019-1414-x
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