Use of photobiomodulation in the treatment of knees osteoarthritis: evaluation of march
DOI:
https://doi.org/10.33448/rsd-v9i10.8098Keywords:
Articular cartilage; Osteoarthritis; Photobiomodulation therapy; LED.Abstract
The aim of the present study was to evaluate the use of photobiomodulation therapy by LED (light emitting diode) in the functional activity of gait in animals with knee OA. For this, 20 male Wistar rats, two months old and with an average body mass of 150 g were used. OA (osteoarthritis) induction was performed on the left knee of all animals through the anterior cruciate ligament transection (ACLT). 4 weeks after OA induction, the rats were randomly divided into a control OA group (OAC): animals without any therapeutic intervention and an OA LED group (OAL): animals irradiated with LED. Gait assessment was performed before the start of LED treatment and after 4 weeks of LED treatment (850 nm, 200 mW, 30 sec, 6 J, 3 times a week). The analysis of gait did not lower the difference between the OAC and OAL group. Thus, it is necessary that an LED photobiomodulation therapy was not able to promote gait alteration in animals.
References
Akhavan, N. S., Ormsbee, L., Johnson, S. A., George, K. S., Foley, E. M., Elam, M. L., Ezzat-Zadeh, Z., Panton, L. B., & Arjmandi, B. H. (2018). Functionality in Middle-Aged and Older Overweight and Obese Individuals with Knee Osteoarthritis. Healthcare (Basel, Switzerland), 6(3), 74.
Appleton, C. T. G., McERLAIN, D. D., Henry, J. L., Holdsworth, D. W., & Beier, F. (2007). Molecular and histological analysis of a new rat model of experimental knee osteoarthritis. Annals of the New York Academy of Sciences, 1117(1), 165-174.
Assis, L., Tim, C., Magri, A., Fernandes, K. R., Vassão, P. G., & Renno, A. C. M. (2018). Interleukin-10 and collagen type II immunoexpression are modulated by photobiomodulation associated to aerobic and aquatic exercises in an experimental model of osteoarthritis. Lasers in medical science, 33(9), 1875-1882.
Cisternas, M. G., Murphy, L., Sacks, J. J., Solomon, D. H., Pasta, D. J., & Helmick, C. G. (2016). Alternative methods for defining osteoarthritis and the impact on estimating prevalence in a US population‐based survey. Arthritis care & research, 68(5), 574-580.
Clark, J. D., Gebhart, G. F., Gonder, J. C., Keeling, M. E., & Kohn, D. F. (1997). The 1996 guide for the care and use of laboratory animals. ILAR journal, 38(1), 41-48.
Clarke, K. A., Heitmeyer, S. A., Smith, A. G., & Taiwo, Y. O. (1997). Gait analysis in a rat model of osteoarthrosis. Physiology & behavior, 62(5), 951-954.
Cunha, J. E., Barbosa, G. M., de Souza Castro, P. A. T., Luiz, B. L. F., Silva, A. C. A., Russo, T. L., ... & Salvini, T. F. (2019). Knee osteoarthritis induces atrophy and neuromuscular junction remodeling in the quadriceps and tibialis anterior muscles of rats. Scientific reports, 9(1), 1-11.
Hamblin, M. R. (2013). Can osteoarthritis be treated with light? Arthritis Res Ther. 15(5),120.
Hasegawa, M., Naito, Y., Yamaguchi, T., Wakabayashi, H., & Sudo, A. (2018). Factors contributing to patient satisfaction and expectations following computer-assisted total knee arthroplasty. The journal of knee surgery, 31(05), 448-452.
Illescas-Montes, R., Melguizo-Rodríguez, L., García-Martínez, O., de Luna-Bertos, E., Manzano-Moreno, F. J., Ruiz, C., & Ramos-Torrecillas, J. (2019). Human Fibroblast Gene Expression Modulation Using 940 NM Diode Laser. Scientific reports, 9(1), 1-7.
Kraan, P. M. (2017). Factors that influence outcome in experimental osteoarthritis. Osteoarthritis Cartilage, 25(3),369-375.
Henrotin, Y., Pesesse, L., & Sanchez, C. (2012). Subchondral bone and osteoarthritis: biological and cellular aspects. Osteoporosis International, 23(8), 847-851.
Jacobs, B. Y., Kloefkorn, H. E., & Allen, K. D. (2014). Gait analysis methods for rodent models of osteoarthritis. Current pain and headache reports, 18(10), 456.
Sit, R. W. S., Chan, K. K. W., Yip, B. H. K., Zhang, D. D., Reeves, K. D., Chan, Y. H., ... & Wong, S. Y. S. (2018). Clinical effectiveness of patella mobilisation therapy versus a waiting list control for knee osteoarthritis: a protocol for a pragmatic randomised clinical trial. BMJ open, 8(3).
Ruan, M. Z., Patel, R. M., Dawson, B. C., Jiang, M. M., & Lee, B. H. L. (2013). Pain, motor and gait assessment of murine osteoarthritis in a cruciate ligament transection model. Osteoarthritis and cartilage, 21(9), 1355-1364.
Pereira, A. S., Shitsuka, D. M., Parreira, F. J., & Shitsuka, R. (2018). Metodologia da pesquisa científica. [e-book].
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2020 Eduardo Santos Trevisan; Cintia Cristina Martignago; Laurita dos Santos; Livia Assis; Daniela Bezerra Macedo; Soraia Salman; Richard Liebano; Carla Roberta Tim
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
1) Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
2) Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
3) Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.
