Characterization and biological activities of polysaccharides extracted from the filamentous fungal cell wall: an updated literature review

Gildomar Lima Valasques Junior; Pâmala Évelin Pires  Cedro; Tátilla Putumujú Santana  Mendes; Alana Caise dos Anjos Miranda; Aldo Barbosa Côrtes Filho; Danyo Maia  Lima; Maíra Mercês  Barreto; Antônio Anderson Freitas  Pinheiro; Lucas Miranda Marques

doi:10.33448/rsd-v9i11.10217

Autores/as

Gildomar Lima Valasques Junior State University of Southwest Bahia https://orcid.org/0000-0002-2877-5313
Pâmala Évelin Pires Cedro State University of Southwest Bahia https://orcid.org/0000-0002-2888-1140
Tátilla Putumujú Santana Mendes State University of Southwest Bahia https://orcid.org/0000-0002-5771-0818
Alana Caise dos Anjos Miranda State University of Southwest Bahia https://orcid.org/0000-0001-6915-5869
Aldo Barbosa Côrtes Filho State University of Southwest Bahia https://orcid.org/0000-0002-8682-4144
Danyo Maia Lima State University of Southwest Bahia https://orcid.org/0000-0003-0593-6927
Maíra Mercês Barreto State University of Southwest Bahia https://orcid.org/0000-0002-6510-2134
Antônio Anderson Freitas Pinheiro Faculdade Maria Milza https://orcid.org/0000-0001-9096-8776
Lucas Miranda Marques Federal University of Bahia https://orcid.org/0000-0002-8276-8149

DOI:

https://doi.org/10.33448/rsd-v9i11.10217

Palabras clave:

Polisacáridos; Hongos filamentosos; Métodos de catacterización.

Resumen

Los hongos filamentosos son organismos eucariotas con diversas aplicaciones industriales y farmacéuticas. Los polisacáridos son componentes de la pared celular de los hongos y otros organismos, y se han informado como productos con numerosas actividades biológicas y aplicaciones en los campos industrial y médico. Este estudio es una revisión narrativa sobre los métodos de caracterización y actividad biológica de polisacáridos aislados de la pared celular de hongos filamentosos. Los polisacáridos que se encuentran con mayor frecuencia en las paredes de las células de los hongos son la quitina, los glucanos y los galactomananos. Estos polisacáridos pueden contener diferentes tipos de enlaces (1-3,1-4, 1-6) de tipos α o β, así como varios tamaños moleculares, y estas variaciones pueden ser responsables de la variedad de actividad biológica que tienen estos polímeros. Los métodos más comunes aplicados para la caracterización de polisacáridos incluyen espectrometría infrarroja, resonancia magnética nuclear y cromatografía de gases acoplada a espectrometría de masas. Las actividades biológicas atribuidas con mayor frecuencia a los polisacáridos de hongos filamentosos incluyen antioxidantes, antiinflamatorios, inmunomoduladores, antinociceptivos, antitumorales e hipoglucémicos. Debido a la variedad de géneros y especies de hongos filamentosos existentes, los estudios de caracterización y la actividad biológica son necesarios para identificar polisacáridos con potencial actividad biológica y que puedan utilizarse con fines medicinales.

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Caracterización y actividades biológicas de polisacáridos extraídos de la pared celular de hongos filamentosos: revisión de la literatura actualizada

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