Caracterização e atividades biológicas de polissacarídeos extraídos da parede celular de fungos filamentosos: uma revisão da literatura atualizada

Autores

DOI:

https://doi.org/10.33448/rsd-v9i11.10217

Palavras-chave:

Polissacarídeos; Fungos filamentosos; Métodos de catacterização.

Resumo

Fungos filamentosos são organismos eucariontes com diversas aplicações industriais e farmacêuticas. Polissacarídeos são componentes da parede celular de fungos, e outros organismos, e têm sido reportados como produtos com inúmeras atividades biológicas e de aplicações na área industrial e médica. Este estudo trata-se de uma revisão narrativa acerca dos métodos de caracterização e atividade biológica de polissacarídeos isolados de da parede celular de fungos filamentosos. Os polissacarídeos mais frequentemente encontrados nas paredes celulares fúngicas são a quitina, glucanas e galactomananas. Esses polissacarídeos podem conter diferentes tipos de ligação (1-3,1-4, 1-6) dos tipos α ou β, como também, diversos tamanhos moleculares, e essas variações podem ser responsáveis pela variedade de atividade biológica que esses polímeros possuem. Os métodos mais comuns aplicados para caracterização dos polissacarídeos, incluem Espectrometria de Infravermelho, Ressonância Magnética Nuclear e Cromatografia Gasosa Acoplada à Espectrometria de Massas. As atividades biológicas mais frequentemente atribuídas à polissacarídeos de fungos filamentosos incluem, antioxidante, anti-inflamatória, imunomoduladora, antinociceptiva, antitumoral e hipoglicemiante. Devido a variedade de gênero e espécies de fungos filamentosos existentes, estudos de caracterização e atividade biológica são necessários, a fim de identificar polissacarídeos com potencial atividade biológica e que possam ser utilizados para fins medicinais.

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28/11/2020

Como Citar

VALASQUES JUNIOR, G. L.; CEDRO, P. Évelin P. .; MENDES, T. P. S. .; MIRANDA, A. C. dos A.; CÔRTES FILHO, A. B.; LIMA, D. M. .; BARRETO, M. M. .; PINHEIRO, A. A. F. .; MARQUES, L. M. Caracterização e atividades biológicas de polissacarídeos extraídos da parede celular de fungos filamentosos: uma revisão da literatura atualizada. Research, Society and Development, [S. l.], v. 9, n. 11, p. e62191110217, 2020. DOI: 10.33448/rsd-v9i11.10217. Disponível em: https://rsdjournal.org/index.php/rsd/article/view/10217. Acesso em: 24 dez. 2024.

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v. 9 n. 11

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Ciências Agrárias e Biológicas

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Copyright (c) 2020 Gildomar Lima Valasques Junior; Pâmala Évelin Pires Cedro; Tátilla Putumujú Santana Mendes; Alana Caise dos Anjos Miranda; Aldo Barbosa Côrtes Filho; Danyo Maia Lima; Maíra Mercês Barreto; Antônio Anderson Freitas Pinheiro; Lucas Miranda Marques

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