Alimentos alergénicos desde una perspectiva regulatoria: una revisión
DOI:
https://doi.org/10.33448/rsd-v10i1.11541Palabras clave:
Alergia alimentaria; Alimentos alergênicos; Etiquetado; Legislación.Resumen
La alergia alimentaria consiste en una reacción inmunomediada que resulta de la ingestión de un alimento alergénico por un individuo sensible. Puede manifestarse de forma leve, con síntomas cutáneos y gastrointestinales, sin embargo puede tener consecuencias graves como la anafilaxia. Como todavía no existe cura para la alergia alimentaria y los tratamientos disponibles no son lo suficientemente seguros y eficaces, restringir el consumo del alimento que provoca la alergia es la intervención más adecuada. Por lo tanto, las personas alérgicas dependen de la información presentada en las etiquetas de los alimentos para elegir, de manera segura, qué productos consumir. Como resultado, muchos países han obligado a declarar los principales alimentos que causan alergias en la etiqueta de los productos envasados. El presente trabajo presenta un análisis de los aspectos regulatorios de este tema en diferentes países. Se pudo evidenciar la evolución de los requisitos regulatorios, aunque las diferencias sustanciales son desfavorables para el comercio internacional y la seguridad alimentaria.
Citas
Agência Nacional de Vigilância Sanitária (ANVISA). (2002). Resolução RDC nº 259, de 20 de setembro de 2002. Regulamento Técnico sobre Rotulagem de Alimentos Embalados. Brasília, DF.
Agência Nacional de Vigilância Sanitária (ANVISA). (2015a). Resolução RDC nº 26, de 02 de julho de 2015. Dispõe sobre os requisitos para rotulagem obrigatória dos principais alimentos que causam alergias alimentares. Brasília, DF.
Agência Nacional de Vigilância Sanitária (ANVISA). (2015b). Relatório de Análise de Contribuições em Consulta Pública e Audiência Pública. http://antigo.anvisa.gov.br/documents/33880/2552856/Relat%C3%B3rio+de+An%C3%A1lise+de+Contribui%C3%A7%C3%B5es+da+CP+29-2014/ca bfa4dc-440b-4841-a713-10e8ddd77838.
Agência Nacional de Vigilância Sanitária (ANVISA). (2017 a). Perguntas e Respostas sobre Rotulagem de Alimentos Alergênicos. (5a ed.), Brasília. 2017. https://www.gov.br/anvisa/pt-br/centraisdeconteudo/publicacoes/alimentos/perguntas-e-respostas/rotulagem-de-alergenicos.pdf.
Agência Nacional de Vigilância Sanitária (ANVISA). (2017 b). Resolução RDC nº 136, de 08 de fevereiro de 2017. Estabelece os requisitos para declaraçãoobrigatória da presença de lactose nos rótulosdos alimentos. Brasília, DF.
Agência Nacional de Vigilância Sanitária (ANVISA). (2018). Guia sobre Programa de Controle de Alergênicos. Guia n° 05/2018 – Versão 2. 2018. http://antigo.anvisa.gov.br/documents/10181/2779039/%281%29Guia+Programa+Controle+de+Alergenicos+versao+2.pdf/69af35f5-cc11-412e-ade5-4d47fef14f5e.
Agência Nacional de Vigilância Sanitária (ANVISA). (2019). Guia para Comprovação da Segurança de Alimentos e Ingredientes. http://antigo.anvisa.gov.br/documents/10181/5355698/Guia+Seguran%C3%A7a+de+Alimentos.pdf/dae93caa-7418-4b9a-97f2-2ec9ebc139e2
Aiking, H., Boer, J. (2020). The next protein transition. Trends in Food Science & Technology, 105, 515-522.
Allen, K. J., et al. (2014). Precautionary labelling of foods for allergen content: are we ready for a global framework? World Allergy Organization Journal, 7(10), 1-14.
Allergen Bureau. (2020). Food Industry Guide to the Voluntary Incidental Trace Allergen Labelling (VITAL) Program Version 3.0. Austrália e Nova Zelândia. October 2012. http://allergenbureau.net/wp-content/uploads/2020/10/Food_Industry_Guide_VITAL_Program_Version_October_2020_VF1.pdf
ASBAI. Associação Brasileira de Alergia e Imunopatologia. (2018). Consenso Brasileiro sobre Alergia Alimentar: Parte 1 - Etiopatogenia, clínica e diagnóstico. Arquivos de Asma Alergia e Imunologia, 2(1).
Australia New Zealand Food Standards Code. (2011). Standard 1.2.3 - Mandatory Warning and Advisory Statements and Declarations. https://www.legislation.gov.au/Details/F2011C00610.
Barnett, J., et al. (2011). How do peanut and nut-allergic consumers use information on the packaging to avoid allergens? Allergy, 66, 969-978.
Bernardo, F. (2006). Perigos sanitários nos alimentos. Revista Segurança e Qualidade Alimentar, 1, 3-7.
Besler, M. Determination of allergens in foods. TrAC Trends in Analytical Chemistry, 20(11), 662-672.
Boyce, J. A., et al. Guidelines for the diagnosis and management of food allergy in the United States: Summary of the NIAID- Sponsored Expert Panel Report. Nutrition, 27(2), 253-267.
Brandtzaeg, P. Food allergy: separating the science from the mythology. Nature Reviews Gastroenterology and Hepatology, 7(7), 380-400.
Codex Alimentarius Commission. (1993). Report of the Twenty-Second Session of the Codex Committee on Food Labelling. http://www.fao.org/fao-who-codexalimentarius/meetings-reports/en/?y=1993&s=1991.
Codex Alimentarius Commission. (2018). Report of The Forty-Fourth Session of The Codex Committee On Food Labelling. http://www.fao.org/fao-who-codexalimentarius/sh-proxy/en/?lnk=1&url=https%253A%252F%252Fworkspace.fao.org%252Fsites%252Fcodex%252FMeetings%252FCX-714-44%252FREPORT%252FREP18_FLe.pdf.
Codex Alimentarius Commission. (2019). Discussion Paper on Allergen Labelling http://www.fao.org/fao-who-codexalimentarius/sh-proxy/en/?lnk=1&url=https%253A%252F%252Fworkspace.fao.org%252Fsites%252Fcodex%252FMeetings%252FCX-714-45%252Fdocuments%252Ffl45_08e.pdf
Codex Alimentarius. (2001). Codex Alimentarius - Food Labeling - Complete Texts – Revised 2001. http://www.fao.org/docrep/005/Y2770E/ y2770e00.htm#Contents.
European Parliament. (2003). Directive 2003/89/EC of the European Parliament and of the Council of 10 November 2003. Amending Directive 2000/13/EC as regards indication of the ingredients present in foodstuffs. Official Journal of the European Union. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L: 2003:308:0015:0018:EN:PDF
European Parliament. (2006). Commission Directive 2006/142/EC of 22 December 2006. Amending Annex IIIa of Directive 2000/13/EC of the European Parliament and of the Council listing the ingredients which must under all circumstances appear on the labelling of foodstuffs. Official Journal of the European Union. https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=OJ:L:2006:368:FULL&from=PT
European Parliament. (2007). Commission Directive 2007/68/EC of 27 November 2007. Amending Annex IIIa to Directive 2000/13/EC of the European Parliament and of the Council as regards certain food ingredients. Official Journal of the European Union. https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32007L0068&from=EN
European Parliament. (2011). Regulation (Eu) No 1169/2011 of the European Parliament and of the Council of 25 October 2011. On the provision of food information to consumers, amending Regulations (EC) No 1924/2006 and (EC) No 1925/2006 of the European Parliament and of the Council, and repealing Commission Directive 87/250/EEC, Council Directive 90/496/EEC, Commission Directive 1999/10/EC, Directive 2000/13/EC of the European Parliament and of the Council, Commission Directives 2002/67/EC and 2008/5/EC and Commission Regulation (EC) No 608/2004. http://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32011R1169&from=EN
Fda - Food and Drug Administration. (1996). Allergens - Label Declaration of Allergenic Substances in Foods; Notice to Manufacturers. 1996. http://www.fda.gov/food/guidanceregulation/
Fda - Food and Drug Administration. (2001). Compliance Policy Guide Sec. 555.250 Statement of Policy for Labeling and Preventing Cross-contact of Common Food Allergens. 2001. http://www.fda.gov/ICECI/ComplianceManuals/CompliancePolicyGuidanceManual/ucm074552.htm
Fda - Food and Drug Administration. (2004). Food Allergen Labeling and Consumer Protection Act of 2004. https://www.fda.gov/media/77570/download
Fda - Food and Drug Administration. (2020 a). Inventory of Notifications Received under 21 U.S.C. 343(w)(7) for Exemptions from Food Allergen Labeling. Online. https://www.fda.gov/food/food-labeling-nutrition/inventory-notifications-received-under-21-usc-343w7-exemptions-food-allergen-labeling
Fda - Food and Drug Administration. (2020 b). Inventory of Petitions Received under 21 U.S.C. 343(w)(6) for Exemptions from Food Allergen Labeling. Online. https://www.fda.gov/food/food-labeling-nutrition/inventory-petitions-received-under-21-usc-343w6-exemptions-food-allergen-labeling
Food Safety Authority of Ireland. (2011). Food Allergens & Labelling Survey June 2011. https://www.fsai.ie/resources.../allergen_labelling _2011.html.html
Fsa - Food Standards Agency. (2015). Allergy: what to consider when labelling food. Reino Unido. 2015. https://www.food.gov.uk/sites/default/files/multimedia/pdfs/publication/allergy-labelling-prepacked.pdf.
Gendel, S. M. (2012). Comparison of international food allergen labeling regulations. Regulatory Toxicology and Pharmacology, 63(2), 279-285.
Gendel, S. M. (2013). The Regulatory Challenge of Food Allergens. Journal of Agricultural Food Chemistry, 61, 5634-5637.
Grimshaw, K. E. C., et al. (2014). Diet and food allergy development during infancy: Birth cohort study findings using prospective food diary data. Allergy, 133(2), 511-519.
Haddeland, U., et al. (2005). Putative regulatory T cells are impaired in cord blood from neonates with hereditary allergy risk. Pedriatr Allergy Immunol., 16, 104-112.
Hirst, B. (2014). Survey of Allergen Advisory Labelling and Allergen Content of UK Retail Pre-Packed Processed Foods. Reading Scientific Services Ltd. https://www.food.gov.uk/science/research/allergy-research/fs241038.
Jackson, W. F. (2003). Food Alergy. 2003. http://ilsi.eu/wp-content/uploads/sites/3/2016/06/C2003Food_All.pdf.
Jones, S. M., Burks, A. W., & Dupont, C. (2014). tate of the art on food allergen immunotherapy: Oral, sublingual, and epicutaneous. American Academy of Allergy, Asthma & Immunology. 2014. http://dx.doi.org/10.1016/j.jaci.2013.12.
Lanser, B. J., Wright, B. L., Orgel, K. A., Vickery, B. P., & Fleischer, D. M. (2015). Current Options for the Treatment of Food Allergy. Pediatr Clin., 62, 1531-1549.
Lee, B. W., Pei-Chi Shek, L., Gerez, I. F. A., Soh, S. E., & Van Bever, H. P. (2008). Food Allergy - Lessons from Asia. World Allergy Organ J., 1(7), 129-133.
Marins, B. R., Araujo, I. S., & Jacob, S. C. (2014). Vigilância Sanitária e direito à comunicação: a rotulagem de alimentos como espaço de cidadania. Vig Sanit Debate, 2(4), 86-95.
Martino, D. J., & Prescott, S. L. (2010). Silent mysteries: epigenetic paradigms could hold the key to conquering the epidemic of allergy and immune disease. Allergy, 65, 7-15.
Mcbride, D., et al. (2012). The EuroPrevall birth cohort study on food allergy: baseline characteristics of 12,000 newborns and their families from nine European countries. Pediatr Allergy Immunol, 23, 230-239.
Mercosul (2015 a). Mercosur/SGT Nº 3/Acta Nº 04/15 LVII Reunión Ordinaria del Subgrupo de Trabajo Nº 3 “Reglamentos Técnicos y Evaluación de La Conformidad”. http://www.puntofocal.gov.ar/doc/lvii_ac_04-15_acta.pdf
Mercosul (2015 b). Mercosur/GMC/Acta Nº 02/15 XLVI Reunión Extraordinaria Del Grupo Mercado Común. http://www.puntofocal.gov.ar/doc/gmc_ex02-15.pdf
Ministério da Saúde. Secretaria de Atenção à Saúde. Departamento de Atenção Básica. (2014). Guia alimentar para a população brasileira. (2a ed.), 1. reimpr. Brasília: Ministério da Saúde, 156 p.
Ministerio de la Salud Pública y Bienertar Social. (2018). Resolución S.G. n° 402. https://www.inan.gov.py/site/?p=1212
Neu, J., & Rushing, J. (2011). Cesarean Versus Vaginal Delivery: Long-term Infant Outcomes and the Hygiene Hypothesis. Clinics in perinatology, 38(2), 321-331.
Odijk, J., et al. (2003). Breastfeeding and allergic disease: a multidisciplinary review of the literature (1966–2001) on the mode of early feeding in infancy and its impact on later atopic manifestations. Allergy, 58, 833-843.
Pereira A. S. et al. (2018). Metodologia da pesquisa científica. [e-book]. Santa Maria. Ed. UAB/NTE/UFSM. https://repositorio.ufsm.br/bitstream/handle/1/15824/Lic_Computacao_Metodologia-Pesquisa-Cientifica.pdf?sequence=1.
Pieretti, M. M., et al. (2009). Audit of manufactured products: Use of allergen advisorylabels and identification of labeling ambiguities. J Allergy Clin Immunol., 124(2), 337-341.
República Oriental del Uruguay (2020). Proyecto para declaración de alérgenos y sustancias que producen reacciones adversas en los rótulos de los alimentos, cualquiera sea su origen, envasados en ausencia del cliente, listos para ser ofrecidos al consumidor (dec. 117/006 del RBN). https://www.gub.uy/ministerio-salud-publica/sites/ministerio-salud-publica/files/2020-09/PROYECTO%20DE%20AL%C3%89RGENOS%20Y%20SUSTANCIAS%20ADVERSAS%20P ARA%20CONSULTA%20P%C3%9ABLICA.pdf.
Santos, A. L. S. β-lactoglobulina em biscoitos semidoces: estudo de degradação no processamento e potencial antigênico, validação de método e avaliação da rotulagem. [Dissertação de Mestrado do Programa de Pós-graduação em Ciência de Alimentos da Universidade Federal de Minas Gerais]. Belo Horizonte: UFMG. https://repositorio.ufmg.br/handle/1843/BUBD-AMUSAB.
Santos, P. P. B. Estudo da degradação e potencial antigênico de proteínas do ovo no processamento de biscoitos semidoces e validação de método imunoenzimático. [Dissertação de Mestrado do Programa de Pós-graduação em Ciência de Alimentos da Universidade Federal de Minas Gerais]. Belo Horizonte: UFMG. https://repositorio.ufmg.br/handle/1843/BUOS-BATFN3
Secretaría de Políticas, Regulación e Institutos, Secretaría De Agregado De Valor. (2017). Resolución Conjunta 11-E/2017. https://www.argentina.gob.ar/normativa/nacional/resoluci%C3%B3n-11-2017-280582/texto
Sicherer, S. H. (2011). Epidemiology of food allergy. The Journal of Allergy and Clinical Immunology, 127(3), 594-602.
Sicherer, S. H., Sampson, H. A. (2018). Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management. The Journal of Allergy and Clinical Immunology, 141(1), 45-58.
Solé, D., et al. (2008). Consenso Brasileiro sobre alergia alimentar: 2007. Revista Brasileira de Alergia e Imunopatologia, 31(2), 64-89.
Zurzolo, G. A., et al. (2013). Precautionary allergen labelling following new labelling practice in Australia. Journal of Paediatrics and Child Health, 49, E306-E310.
Zurzolo, G. A., et al. (2016). Is advising food allergic patients to avoid food with precautionary allergen labelling out of date? Curr Opin Allergy Clin Immunol., 16(3), 272-277.
Descargas
Publicado
Cómo citar
Número
Sección
Licencia
Derechos de autor 2021 Marina de Paula Penna e Palhares; Pedro Paulo Borges dos Santos; Ana Luiza Soares dos Santos; Cristiane Lúcia Goddard; Scheilla Vitorino Carvalho de Souza
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
Los autores que publican en esta revista concuerdan con los siguientes términos:
1) Los autores mantienen los derechos de autor y conceden a la revista el derecho de primera publicación, con el trabajo simultáneamente licenciado bajo la Licencia Creative Commons Attribution que permite el compartir el trabajo con reconocimiento de la autoría y publicación inicial en esta revista.
2) Los autores tienen autorización para asumir contratos adicionales por separado, para distribución no exclusiva de la versión del trabajo publicada en esta revista (por ejemplo, publicar en repositorio institucional o como capítulo de libro), con reconocimiento de autoría y publicación inicial en esta revista.
3) Los autores tienen permiso y son estimulados a publicar y distribuir su trabajo en línea (por ejemplo, en repositorios institucionales o en su página personal) a cualquier punto antes o durante el proceso editorial, ya que esto puede generar cambios productivos, así como aumentar el impacto y la cita del trabajo publicado.